3T3Y
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3HAO
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![BU of 3hao by Molmil](/molmil-images/mine/3hao) | |
6UCU
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![BU of 6ucu by Molmil](/molmil-images/mine/6ucu) | Cryo-EM structure of the mitochondrial TOM complex from yeast (dimer) | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ... | Authors: | Park, E, Tucker, K. | Deposit date: | 2019-09-17 | Release date: | 2019-11-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution. Nat.Struct.Mol.Biol., 26, 2019
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6UC0
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![BU of 6uc0 by Molmil](/molmil-images/mine/6uc0) | Isolated S3D-cofilin bound to an actin filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Huehn, A.R, Bibeau, J.P, Schramm, A.C, Cao, W, De La Cruz, E.M, Sindelar, C.V. | Deposit date: | 2019-09-13 | Release date: | 2020-01-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments. Proc.Natl.Acad.Sci.USA, 117, 2020
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6O4O
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![BU of 6o4o by Molmil](/molmil-images/mine/6o4o) | The structure of human interleukin 11 | Descriptor: | CHLORIDE ION, Interleukin-11, SULFATE ION | Authors: | Metcalfe, R.D, Griffin, M.D.W. | Deposit date: | 2019-02-28 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structure of the extracellular domains of human interleukin 11 alpha receptor reveals mechanisms of cytokine engagement. J.Biol.Chem., 295, 2020
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3GKE
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![BU of 3gke by Molmil](/molmil-images/mine/3gke) | Crystal Structure of Dicamba Monooxygenase | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DdmC, ... | Authors: | Wilson, M.A, Dumitru, R, Jiang, W.Z, Weeks, D.P. | Deposit date: | 2009-03-10 | Release date: | 2009-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation. J.Mol.Biol., 392, 2009
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6O4U
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![BU of 6o4u by Molmil](/molmil-images/mine/6o4u) | Co-crystal structure of Mcl1 with inhibitor | Descriptor: | (2~{S})-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-~{N}-(2-methylpropylsulfonyl)-2,3-dihydro-1,4-benzoxazine-6-carboxamide, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Huang, X. | Deposit date: | 2019-03-01 | Release date: | 2020-03-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Conformational Restriction Toward the Discovery of Macrocyclic MCL1 Inhibitors that Display Efficacy in Mouse Xenograft Models To Be Published
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6O4W
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![BU of 6o4w by Molmil](/molmil-images/mine/6o4w) | Binary complex of native hAChE with Donepezil | Descriptor: | 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, Acetylcholinesterase, GLYCEROL, ... | Authors: | Gerlits, O, Kovalevsky, A, Radic, Z. | Deposit date: | 2019-03-01 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies. Chem.Biol.Interact., 309, 2019
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3UJK
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![BU of 3ujk by Molmil](/molmil-images/mine/3ujk) | Crystal structure of protein phosphatase ABI2 | Descriptor: | MAGNESIUM ION, Protein phosphatase 2C 77 | Authors: | Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E. | Deposit date: | 2011-11-07 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science, 335, 2012
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3T2O
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![BU of 3t2o by Molmil](/molmil-images/mine/3t2o) | E. coli (lacZ) beta-galactosidase (S796D) | Descriptor: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | Deposit date: | 2011-07-22 | Release date: | 2012-01-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
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6O52
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3MPI
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![BU of 3mpi by Molmil](/molmil-images/mine/3mpi) | Structure of the glutaryl-coenzyme A dehydrogenase glutaryl-CoA complex | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase, glutaryl-coenzyme A | Authors: | Wischgoll, S, Warkentin, E, Boll, M, Ermler, U. | Deposit date: | 2010-04-27 | Release date: | 2010-08-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for promoting and preventing decarboxylation in glutaryl-coenzyme a dehydrogenases. Biochemistry, 49, 2010
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6O84
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![BU of 6o84 by Molmil](/molmil-images/mine/6o84) | Cryo-EM structure of OTOP3 from xenopus tropicalis | Descriptor: | LOC100127796 protein,LOC100127796 protein,OTOP3,LOC100127796 protein,LOC100127796 protein | Authors: | Chen, Q.F, Bai, X.C, Jiang, Y.X. | Deposit date: | 2019-03-08 | Release date: | 2019-04-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural and functional characterization of an otopetrin family proton channel. Elife, 8, 2019
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3GNP
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![BU of 3gnp by Molmil](/molmil-images/mine/3gnp) | Crystal Structure of a Rice Os3BGlu6 Beta-Glucosidase with Octyl-Beta-D-Thio-Glucoside | Descriptor: | GLYCEROL, Os03g0212800 protein, octyl 1-thio-beta-D-glucopyranoside | Authors: | Seshadri, S, Akiyama, T, Opassiri, R, Kuaprasert, B, Cairns, J.R.K. | Deposit date: | 2009-03-17 | Release date: | 2009-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and enzymatic characterization of Os3BGlu6, a rice {beta}-glucosidase hydrolyzing hydrophobic glycosides and (1->3)- and (1->2)-linked disaccharides. Plant Physiol., 2009
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6TXS
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![BU of 6txs by Molmil](/molmil-images/mine/6txs) | The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide | Descriptor: | CD44 antigen, Moesin | Authors: | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-14 | Release date: | 2020-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
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3MQP
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![BU of 3mqp by Molmil](/molmil-images/mine/3mqp) | Crystal Structure of human BFL-1 in complex with NOXA BH3 peptide, Northeast Structural Genomics Consortium Target HR2930 | Descriptor: | Bcl-2-related protein A1, Phorbol-12-myristate-13-acetate-induced protein 1 | Authors: | Guan, R, Xiao, R, Zhao, L, Acton, T.B, Gelinas, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-04-28 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal Structure of human BFL-1 in complex with NOXA BH3 peptide To be Published
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6OE3
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![BU of 6oe3 by Molmil](/molmil-images/mine/6oe3) | Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-7-fluoro-2-naphthonitrile (JLJ635), a Non-nucleoside Inhibitor | Descriptor: | 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-7-fluoronaphthalene-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... | Authors: | Bertoletti, N, Kudalkar, S.N, Anderson, K.S, Cisneros Trigo, J.A, Jorgensen, W.L. | Deposit date: | 2019-03-27 | Release date: | 2019-05-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV. Antiviral Res., 167, 2019
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3UOV
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![BU of 3uov by Molmil](/molmil-images/mine/3uov) | Crystal Structure of OTEMO (FAD bound form 1) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, OTEMO | Authors: | Shi, R, Matte, A, Cygler, M, Lau, P. | Deposit date: | 2011-11-17 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.045 Å) | Cite: | Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-{Delta}(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453. Appl.Environ.Microbiol., 78, 2012
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3UP5
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![BU of 3up5 by Molmil](/molmil-images/mine/3up5) | Crystal Structure of OTEMO complex with FAD and NADP (form 4) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OTEMO | Authors: | Shi, R, Matte, A, Cygler, M, Lau, P. | Deposit date: | 2011-11-17 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.453 Å) | Cite: | Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-{Delta}(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453. Appl.Environ.Microbiol., 78, 2012
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4BPD
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![BU of 4bpd by Molmil](/molmil-images/mine/4bpd) | Structure determination of an integral membrane kinase | Descriptor: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, DIACYLGLYCEROL KINASE, ZINC ION | Authors: | Li, D, Boland, C, Caffrey, M. | Deposit date: | 2013-05-24 | Release date: | 2014-05-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Cell-Free Expression and in Meso Crystallisation of an Integral Membrane Kinase for Structure Determination. Cell.Mol.Life Sci., 71, 2014
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6OFX
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![BU of 6ofx by Molmil](/molmil-images/mine/6ofx) | Non-rotated ribosome (Structure I) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-01 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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3UTN
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![BU of 3utn by Molmil](/molmil-images/mine/3utn) | Crystal structure of Tum1 protein from Saccharomyces cerevisiae | Descriptor: | DIMETHYL SULFOXIDE, SULFATE ION, Thiosulfate sulfurtransferase TUM1 | Authors: | Qiu, R, Wang, F, Liu, M, Ji, C, Gong, W. | Deposit date: | 2011-11-26 | Release date: | 2012-10-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the Tum1 protein from the yeast Saccharomyces cerevisiae. Protein Pept.Lett., 19, 2012
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6OHT
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![BU of 6oht by Molmil](/molmil-images/mine/6oht) | Structure of EBP and U18666A | Descriptor: | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, 3beta-(2-Diethylaminoethoxy)androst-5-en-17-one | Authors: | Long, T, Li, X. | Deposit date: | 2019-04-06 | Release date: | 2019-06-19 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition. Nat Commun, 10, 2019
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3T8B
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![BU of 3t8b by Molmil](/molmil-images/mine/3t8b) | Crystal structure of Mycobacterium tuberculosis MenB with altered hexameric assembly | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | Deposit date: | 2011-08-01 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
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6OIN
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![BU of 6oin by Molmil](/molmil-images/mine/6oin) | Crystal structure of MYST acetyltransferase domain in complex with inhibitor CTX-124143 | Descriptor: | 2-fluoro-N'-[(naphthalen-2-yl)sulfonyl]benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ... | Authors: | Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B. | Deposit date: | 2019-04-09 | Release date: | 2019-07-03 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A. J.Med.Chem., 62, 2019
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