6O4W
Binary complex of native hAChE with Donepezil
Summary for 6O4W
Entry DOI | 10.2210/pdb6o4w/pdb |
Descriptor | Acetylcholinesterase, GLYCEROL, 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 122135.52 |
Authors | Gerlits, O.,Kovalevsky, A.,Radic, Z. (deposition date: 2019-03-01, release date: 2019-06-19, Last modification date: 2023-10-11) |
Primary citation | Gerlits, O.,Ho, K.Y.,Cheng, X.,Blumenthal, D.,Taylor, P.,Kovalevsky, A.,Radic, Z. A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies. Chem.Biol.Interact., 309:108698-108698, 2019 Cited by PubMed: 31176713DOI: 10.1016/j.cbi.2019.06.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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