3V62
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![BU of 3v62 by Molmil](/molmil-images/mine/3v62) | Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 | Descriptor: | ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... | Authors: | Armstrong, A.A, Mohideen, F, Lima, C.D. | Deposit date: | 2011-12-18 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
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2F55
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![BU of 2f55 by Molmil](/molmil-images/mine/2f55) | Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna | Descriptor: | 5'-D(P*(DU)P*(DU)P*(DU))-3', 5'-D(P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU)P*(DU))-3', SULFATE ION, ... | Authors: | Lu, J.Z, Jordan, J.B, Sakon, J. | Deposit date: | 2005-11-25 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus J.Biol.Chem., 281, 2006
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1Z7I
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![BU of 1z7i by Molmil](/molmil-images/mine/1z7i) | |
1QKJ
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![BU of 1qkj by Molmil](/molmil-images/mine/1qkj) | T4 Phage B-Glucosyltransferase, Substrate Binding and Proposed Catalytic Mechanism | Descriptor: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | Authors: | Morera, S, Imberty, I, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S. | Deposit date: | 1999-07-22 | Release date: | 1999-07-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | T4 Phage Beta-Glucosyltransferase: Substrate Binding and Proposed Catalytic Mechanism J.Mol.Biol., 292, 1999
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4AQX
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![BU of 4aqx by Molmil](/molmil-images/mine/4aqx) | Crystal structure of I-CreI complexed with its target methylated at position plus 2 (in the b strand) in the presence of magnesium | Descriptor: | 5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*5CM)-3', 5'-D(*GP*AP*CP*AP*GP*TP*TP*TP*GP*GP)-3', 5'-D(*GP*AP*CP*GP*TP*TP*TP*TP*GP*AP)-3', ... | Authors: | Valton, J, Daboussi, F, Leduc, S, Redondo, P, Macmaster, R, Molina, R, Montoya, G, Duchateau, P. | Deposit date: | 2012-04-19 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | 5'-Cytosine-Phosphoguanine (Cpg) Methylation Impacts the Activity of Natural and Engineered Meganucleases. J.Biol.Chem., 287, 2012
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4AQU
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![BU of 4aqu by Molmil](/molmil-images/mine/4aqu) | Crystal structure of I-CreI complexed with its target methylated at position plus 2 (in the b strand) in the presence of calcium | Descriptor: | 5'-D(*DCP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*5CMP *GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', 5'-D(*DTP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*DAP *GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', CALCIUM ION, ... | Authors: | Valton, J, Daboussi, F, Leduc, S, Redondo, P, Macmaster, R, Molina, R, Montoya, G, Duchateau, P. | Deposit date: | 2012-04-19 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | 5'-Cytosine-Phosphoguanine (Cpg) Methylation Impacts the Activity of Natural and Engineered Meganucleases. J.Biol.Chem., 287, 2012
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4ENN
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1DL4
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![BU of 1dl4 by Molmil](/molmil-images/mine/1dl4) | THE SOLUTION STRUCTURE OF A BAY-REGION 1S-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE | Descriptor: | 1R,2S,3R,4S-TETRAHYDRO-BENZO[A]ANTHRACENE-2,3,4-TRIOL, DNA (5'-D(*CP*GP*GP*AP*CP*(BZA)AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') | Authors: | Li, Z, Kim, H.-Y, Tamura, P.J, Harris, C.M, Harris, T.M, Stone, M.P. | Deposit date: | 1999-12-08 | Release date: | 2000-01-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Intercalation of the (1S,2R,3S,4R)-N6-[1-(1,2,3,4-tetrahydro-2,3, 4-trihydroxybenz[a]anthracenyl)]-2'-deoxyadenosyl adduct in an oligodeoxynucleotide containing the human N-ras codon 61 sequence. Biochemistry, 38, 1999
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7V3U
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![BU of 7v3u by Molmil](/molmil-images/mine/7v3u) | Cryo-EM structure of MCM double hexamer with structured Mcm4-NSD | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | Authors: | Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. | Deposit date: | 2021-08-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase. Nat Commun, 13, 2022
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7V3V
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![BU of 7v3v by Molmil](/molmil-images/mine/7v3v) | Cryo-EM structure of MCM double hexamer bound with DDK in State I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ... | Authors: | Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. | Deposit date: | 2021-08-11 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase. Nat Commun, 13, 2022
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3QMH
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![BU of 3qmh by Molmil](/molmil-images/mine/3qmh) | Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1 | Descriptor: | 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', CpG-binding protein, ZINC ION | Authors: | Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-02-04 | Release date: | 2011-02-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun, 2, 2011
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4H5Q
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3QMI
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![BU of 3qmi by Molmil](/molmil-images/mine/3qmi) | Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-ACGT) by the CXXC Domain of CFP1 | Descriptor: | 5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3', CpG-binding protein, DI(HYDROXYETHYL)ETHER, ... | Authors: | Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2011-02-04 | Release date: | 2011-02-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun, 2, 2011
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5Y59
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![BU of 5y59 by Molmil](/molmil-images/mine/5y59) | Crystal structure of Ku80 and Sir4 | Descriptor: | ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | Deposit date: | 2017-08-08 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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7PDS
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![BU of 7pds by Molmil](/molmil-images/mine/7pds) | The structure of PriRep1 with dsDNA | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Similar to D. nodosus vapE, ... | Authors: | Qiao, C.C, Mir Sanchis, I. | Deposit date: | 2021-08-06 | Release date: | 2022-07-13 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Staphylococcal self-loading helicases couple the staircase mechanism with inter domain high flexibility. Nucleic Acids Res., 50, 2022
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6EXT
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![BU of 6ext by Molmil](/molmil-images/mine/6ext) | |
7W8G
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![BU of 7w8g by Molmil](/molmil-images/mine/7w8g) | Cryo-EM structure of MCM double hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | Authors: | Cheng, J, Li, N, Tye, B, Zhai, Y, Gao, N. | Deposit date: | 2021-12-07 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase. Nat Commun, 13, 2022
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4HIV
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![BU of 4hiv by Molmil](/molmil-images/mine/4hiv) | Structure of actinomycin D d(ATGCGGCAT) complex | Descriptor: | ACTINOMYCIN D, DNA (5'-D(*AP*TP*GP*CP*GP*GP*CP*AP*T)-3') | Authors: | Lo, Y.S, Tseng, W.H, Hou, M.H. | Deposit date: | 2012-10-12 | Release date: | 2013-05-08 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats. Nucleic Acids Res., 41, 2013
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6EXU
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3W99
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![BU of 3w99 by Molmil](/molmil-images/mine/3w99) | Crystal Structure of Human Nucleosome Core Particle lacking H4 N-terminal region | Descriptor: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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3W98
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![BU of 3w98 by Molmil](/molmil-images/mine/3w98) | Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | Descriptor: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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8Q4D
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![BU of 8q4d by Molmil](/molmil-images/mine/8q4d) | IstA-IstB(E167Q) Strand Transfer Complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (118-MER) / TIR-transferred strand, ... | Authors: | de la Gandara, A, Spinola-Amilibia, M, Araujo-Bazan, L, Nunez-Ramirez, R, Berger, J.M, Arias-Palomo, E. | Deposit date: | 2023-08-06 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Molecular basis for transposase activation by a dedicated AAA+ ATPase. Nature, 630, 2024
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1LAQ
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![BU of 1laq by Molmil](/molmil-images/mine/1laq) | Solution Structure of the B-DNA Duplex CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct with the Deoxyribose at C20 Opposite PdG in the C2' Endo Conformation. | Descriptor: | 5'-D(*CP*GP*CP*GP*GP*AP*(DNR)P*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3' | Authors: | Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P. | Deposit date: | 2002-03-29 | Release date: | 2002-04-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2. Chem.Res.Toxicol., 15, 2002
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3W96
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![BU of 3w96 by Molmil](/molmil-images/mine/3w96) | Crystal Structure of Human Nucleosome Core Particle lacking H2A N-terminal region | Descriptor: | 146-mer DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
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2O3M
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![BU of 2o3m by Molmil](/molmil-images/mine/2o3m) | Monomeric G-DNA tetraplex from human C-kit promoter | Descriptor: | 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Burge, S, Neidle, S, Patel, D.J. | Deposit date: | 2006-12-01 | Release date: | 2007-05-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. J.Am.Chem.Soc., 129, 2007
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