PDB: 1195 resultsInfo pagesStatus searchChemie searchBIRD

---

1AL6	CHICKEN CITRATE SYNTHASE COMPLEX WITH N-HYDROXYAMIDO-COA AND OXALOACETATE Descriptor: CITRATE SYNTHASE, N-HYDROXYAMIDOCARBOXYMETHYLDETHIA COENZYME *A, OXALOACETATE ION Authors: Usher, K.C, Remington, S.J. Deposit date: 1997-06-12 Release date: 1997-12-24 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Mechanisms of Enzyme-Catalyzed Deprotonation of Acetyl-Coenzyme A To be Published
5TDZ	TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Hu, J, Fraser, M.E. Deposit date: 2016-09-20 Release date: 2017-08-09 Last modified: 2017-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TDF	TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate Descriptor: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Hu, J, Fraser, M.E. Deposit date: 2016-09-19 Release date: 2017-08-09 Last modified: 2017-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
6O0H	Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143 Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate Authors: Wei, J, Tong, L. Deposit date: 2019-02-16 Release date: 2019-04-17 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Nature, 568, 2019
5TET	TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate Descriptor: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ... Authors: Hu, J, Fraser, M.E. Deposit date: 2016-09-22 Release date: 2017-08-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TE1	C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate Descriptor: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ATP-citrate synthase, PHOSPHATE ION, ... Authors: Hu, J, Fraser, M.E. Deposit date: 2016-09-20 Release date: 2017-08-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
6UV5	Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate Descriptor: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION Authors: Wei, X, Marmorstein, R. Deposit date: 2019-11-01 Release date: 2019-12-25 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
5TDM	TEV Cleaved Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate and ADP Descriptor: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Hu, J, Fraser, M.E. Deposit date: 2016-09-19 Release date: 2017-08-09 Last modified: 2017-08-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
8S97	C143W variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis Descriptor: 1,2-ETHANEDIOL, citrate synthase Authors: Pathirage, R, Ronning, D. Deposit date: 2023-03-27 Release date: 2023-06-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GLB	Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate Descriptor: 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase Authors: Pathirage, R, Ronning, D, Favrot, L. Deposit date: 2023-03-21 Release date: 2023-06-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GMK	Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ... Authors: Pathirage, R, Ronning, D, Yamsek, M. Deposit date: 2023-03-26 Release date: 2023-06-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GM9	Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis Descriptor: 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Pathirage, R, Ronning, D, Favrot, L. Deposit date: 2023-03-24 Release date: 2023-06-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GLL	R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... Authors: Pathirage, R, Ronning, D, Petit, C. Deposit date: 2023-03-22 Release date: 2023-06-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14, 2023
8GR9	Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomyces cerevisiae in complex with oxaloacetate and coenzyme-A Descriptor: CHLORIDE ION, COENZYME A, Citrate synthase, ... Authors: Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. Deposit date: 2022-09-01 Release date: 2023-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
8GR8	Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomycescerevisiae Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Citrate synthase, ... Authors: Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. Deposit date: 2022-09-01 Release date: 2023-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
8GQZ	Crystal structure of mitochondrial citrate synthase (Cit1) from Saccharomyces cerevisiae Descriptor: ACETATE ION, CHLORIDE ION, Citrate synthase, ... Authors: Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. Deposit date: 2022-08-31 Release date: 2023-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
2IBP	Crystal Structure of Citrate Synthase from Pyrobaculum aerophilum Descriptor: ACETATE ION, Citrate synthase, MAGNESIUM ION Authors: Boutz, D.R, Yeates, T.O, Cascio, D. Deposit date: 2006-09-11 Release date: 2007-05-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of a thermophilic protein complex stabilized by topologically interlinked chains. J.Mol.Biol., 368, 2007
6HXP	Structure of citryl-CoA lyase from Hydrogenobacter thermophilus Descriptor: COENZYME A, Citryl-CoA lyase, SULFATE ION Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
5JNP	Crystal structure of a rice (Oryza Sativa) cellulose synthase plant conserved region (P-CR) Descriptor: CITRATE ANION, GLYCEROL, PHOSPHATE ION, ... Authors: Rushton, P.S, Olek, A.T, Makowski, L, Badger, J, Steussy, C.N, Carpita, N.C, Stauffacher, C.V. Deposit date: 2016-04-30 Release date: 2016-12-28 Last modified: 2019-12-04 Method: X-RAY DIFFRACTION (2.404 Å) Cite: Rice Cellulose SynthaseA8 Plant-Conserved Region Is a Coiled-Coil at the Catalytic Core Entrance. Plant Physiol., 173, 2017
5F35	Structure of quinolinate synthase in complex with citrate Descriptor: CITRATE ANION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... Authors: Volbeda, A, Fontecilla-Camps, J.C. Deposit date: 2015-12-02 Release date: 2016-08-31 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
3PFF	Truncated human atp-citrate lyase with ADP and tartrate bound Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, L(+)-TARTARIC ACID, ... Authors: Fraser, M.E, Sun, T. Deposit date: 2010-10-28 Release date: 2011-10-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase. Acta Crystallogr.,Sect.F, 67, 2011
5LQM	Structure of quinolinate synthase Y21F mutant in complex with citrate Descriptor: CITRATE ANION, IRON/SULFUR CLUSTER, Quinolinate synthase A Authors: Volbeda, A, Fontecilla-Camps, J.C. Deposit date: 2016-08-17 Release date: 2016-08-31 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product. J.Am.Chem.Soc., 138, 2016
6XOW	CryoEM structure of human presequence protease in partial close state 2, induced by presequence of citrate synthase Descriptor: Presequence protease, mitochondrial Authors: Liang, W.G, Tang, W. Deposit date: 2020-07-07 Release date: 2021-07-07 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: CryoEM structure of human presequence protease in partial open state 2, induced by presequence of citrate synthase To Be Published
2BO4	Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase Descriptor: CITRATE ANION, MANNOSYLGLYCERATE SYNTHASE Authors: Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. Deposit date: 2005-04-07 Release date: 2005-06-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase Nat.Struct.Mol.Biol., 12, 2005
2WVK	Mannosyl-3-phosphoglycerate synthase from Thermus thermophilus HB27 apoprotein Descriptor: CITRATE ANION, MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE, ZINC ION Authors: Goncalves, S, Borges, N, Esteves, A.M, Victor, B, Soares, C.M, Santos, H, Matias, P.M. Deposit date: 2009-10-19 Release date: 2010-03-31 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Structural Analysis of Thermus Thermophilus Hb27 Mannosyl-3-Phosphoglycerate Synthase Provides Evidence for a Second Catalytic Metal Ion and New Insight Into the Retaining Mechanism of Glycosyltransferases. J.Biol.Chem., 285, 2010

<12345678910111213141516>