1OYV
 
 | | Crystal structure of tomato inhibitor-II in a ternary complex with subtilisin Carlsberg | | Descriptor: | CALCIUM ION, Subtilisin Carlsberg, Wound-induced proteinase inhibitor-II | | Authors: | Barrette-Ng, I.H, Ng, K.K, Cherney, M.M, Pearce, G, Ryan, C.A, James, M.N. | | Deposit date: | 2003-04-07 | | Release date: | 2003-07-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis of inhibition revealed by a 1:2 complex of the two-headed tomato inhibitor-II and subtilisin Carlsberg
J.Biol.Chem., 278, 2003
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6XN4
 | | Structure of the Lactococcus lactis Csm CTR_3:2 CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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6XN3
 | | Structure of the Lactococcus lactis Csm CTR_4:3 CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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6XN7
 | | Structure of the Lactococcus lactis Csm NTR CRISPR-Cas Complex | | Descriptor: | CRISPR-associated protein Cas10, CRISPR-associated protein Csm2, CRISPR-associated protein Csm3, ... | | Authors: | Rai, J, Sridhara, S, Li, H. | | Deposit date: | 2020-07-02 | | Release date: | 2022-01-12 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural and biochemical characterization of in vivo assembled Lactococcus lactis CRISPR-Csm complex.
Commun Biol, 5, 2022
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1P9Q
 | | Structure of a hypothetical protein AF0491 from Archaeoglobus fulgidus | | Descriptor: | Hypothetical protein AF0491 | | Authors: | Savchenko, A, Evdokimova, E, Skarina, T, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A. | | Deposit date: | 2003-05-12 | | Release date: | 2004-06-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.
J.Biol.Chem., 280, 2005
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8T2S
 | | Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state | | Descriptor: | AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ... | | Authors: | Xu, L, Liu, T, Chung, K, Pyle, A.M. | | Deposit date: | 2023-06-06 | | Release date: | 2023-11-22 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
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5MQ8
 | | Crystal structure of Rae1 (YacP) from Bacillus subtilis | | Descriptor: | GLYCEROL, Uncharacterized protein YacP | | Authors: | Piton, J, Gilet, L, Pellegrini, O, Leroy, M, Figaro, S, Condon, C. | | Deposit date: | 2016-12-20 | | Release date: | 2017-04-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis.
EMBO J., 36, 2017
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8FAM
 | | Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature | | Descriptor: | Synaptotagmin | | Authors: | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. | | Deposit date: | 2022-11-28 | | Release date: | 2023-07-19 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
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8FAF
 | | Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature | | Descriptor: | Synaptotagmin | | Authors: | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B. | | Deposit date: | 2022-11-26 | | Release date: | 2023-07-19 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
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4BUJ
 | | Crystal structure of the S. cerevisiae Ski2-3-8 complex | | Descriptor: | ANTIVIRAL HELICASE SKI2, ANTIVIRAL PROTEIN SKI8, SULFATE ION, ... | | Authors: | Halbach, F, Reichelt, P, Rode, M, Conti, E. | | Deposit date: | 2013-06-20 | | Release date: | 2013-08-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | The Yeast Ski Complex: Crystal Structure and RNA Channeling to the Exosome Complex.
Cell(Cambridge,Mass.), 154, 2013
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4A75
 | | The Lin28b Cold shock domain in complex with hexathymidine. | | Descriptor: | 5'-D(*TP*TP*TP*TP*TP*TP)-3', LIN28 COLD SHOCK DOMAIN, THIOCYANATE ION | | Authors: | Mayr, F, Schuetz, A, Doege, N, Heinemann, U. | | Deposit date: | 2011-11-11 | | Release date: | 2012-09-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Nucleic Acids Res., 40, 2012
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5MQ9
 | | Crystal structure of Rae1 (YacP) from Bacillus subtilis (W164L mutant) | | Descriptor: | SULFATE ION, Uncharacterized protein YacP | | Authors: | Piton, J, Gilet, L, Pellegrini, O, Leroy, M, Figaro, S, Condon, C. | | Deposit date: | 2016-12-20 | | Release date: | 2017-04-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.174 Å) | | Cite: | Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis.
EMBO J., 36, 2017
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1NTS
 | | 5'(dCCPUPCPCPUPUP)3':3'(rAGGAGGAAA)5', where P=propynyl | | Descriptor: | 5'-D(*(5PC)P*(5PC)P*(PDU)P*(5PC)P*(5PC)P*(PDU)P*(PDU))-3', 5'-R(*AP*AP*AP*GP*GP*AP*GP*GP*A)-3' | | Authors: | Znosko, B.M, Barnes III, T.W, Krugh, T.R, Turner, D.H. | | Deposit date: | 2003-01-30 | | Release date: | 2003-06-10 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR Studies of DNA Single Strands and DNA:RNA Hybrids With and Without 1-Propynylation at C5 of Oligopyrimidines
J.Am.Chem.Soc., 125, 2003
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7YG7
 | | Structure of the Spring Viraemia of Carp Virus ribonucleoprotein Complex | | Descriptor: | Nucleoprotein, RNA (99-mer) | | Authors: | Liu, B, Wang, Z.X, Yang, T, Yu, D.Q, Ouyang, Q. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-15 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening.
J.Virol., 97, 2023
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1QCG
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4ZNP
 | | The structure of A pfI Riboswitch Bound to ZMP | | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, pfI Riboswitch | | Authors: | Ren, A, Patel, D.J, Rajashankar, R.K. | | Deposit date: | 2015-05-05 | | Release date: | 2015-08-26 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism.
Structure, 23, 2015
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4KB7
 | | HCV NS5B GT1B N316Y with CMPD 32 | | Descriptor: | 5-cyclopropyl-2-(4-fluorophenyl)-6-[{2-[(3R)-1-hydroxy-1,3-dihydro-2,1-benzoxaborol-3-yl]ethyl}(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide, HCV Polymerase | | Authors: | Williams, S.P, Kahler, K.M, Shotwell, J.B. | | Deposit date: | 2013-04-23 | | Release date: | 2013-05-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase.
J.Med.Chem., 57, 2014
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1NTT
 | | 5'(dCPCPUPCPCPUPUP)3':(rAGGAGGAAA)5', where P=propynyl | | Descriptor: | 5'-D(*CP*(5PC)P*(PDU)P*(5PC)P*(5PC)P*(PDU)P*(PDU))-3', 5'-R(*AP*AP*AP*GP*GP*AP*GP*GP*A)-3' | | Authors: | Znosko, B.M, Barnes III, T.W, Krugh, T.R, Turner, D.H. | | Deposit date: | 2003-01-30 | | Release date: | 2003-06-10 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR Studies of DNA Single Strands and DNA:RNA Hybrids With and Without 1-Propynylation at C5 of Oligopyrimidines
J.Am.Chem.Soc., 125, 2003
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6UE5
 | | Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide | | Descriptor: | 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... | | Authors: | Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E. | | Deposit date: | 2019-09-20 | | Release date: | 2019-12-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
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1QCI
 | | LOW TEMPERATURE STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN COMPLEXED WITH ADENINE | | Descriptor: | ADENINE, POKEWEED ANTIVIRAL PROTEIN | | Authors: | Kurinov, I.V, Myers, D.E, Irvin, J.D, Uckun, F.M. | | Deposit date: | 1999-05-05 | | Release date: | 1999-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs.
Protein Sci., 8, 1999
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3TZR
 | | Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site | | Descriptor: | (8R)-8-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-1,7,8,9-tetrahydrochromeno[5,6-d]imidazol-2-amine, 5'-R(*CP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*CP*C)-3', 5'-R(*GP*GP*UP*CP*GP*UP*GP*CP*AP*GP*CP*CP*UP*CP*GP*G)-3', ... | | Authors: | Dibrov, S.M, Ding, K, Brunn, N, Parker, M.A, Bergdahl, B.M, Wyles, D.L, Hermann, T. | | Deposit date: | 2011-09-27 | | Release date: | 2012-03-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.212 Å) | | Cite: | Structure of a Riboswitch in the Hepatitis C Virus Internal Ribosome Entry Site
To be Published
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2XP1
 | | Structure of the tandem SH2 domains from Antonospora locustae transcription elongation factor Spt6 | | Descriptor: | CHLORIDE ION, SPT6, SULFATE ION | | Authors: | Diebold, M.-L, Koch, M, Cavarelli, J, Romier, C. | | Deposit date: | 2010-08-24 | | Release date: | 2010-09-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Noncanonical Tandem Sh2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II.
J.Biol.Chem., 285, 2010
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6JIE
 | | YaeO bound to Magnesium from Vibrio cholerae O395 | | Descriptor: | MAGNESIUM ION, YaeO | | Authors: | Pal, K, Yadav, M, Sen, U. | | Deposit date: | 2019-02-20 | | Release date: | 2019-12-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Vibrio cholerae YaeO is a Structural Homologue of RNA Chaperone Hfq that Inhibits Rho-dependent Transcription Termination by Dissociating its Hexameric State.
J.Mol.Biol., 431, 2019
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1QCJ
 | | LOW TEMPERATURE COMPLEX OF POKEWEED ANTIVIRAL PROTEIN WITH PTEORIC ACID | | Descriptor: | 2-AMINO-6-[(4-CARBOXY-PHENYLAMINO)-METHYL]-4-HYDROXY-PTERIDIN-1-IUM, POKEWEED ANTIVIRAL PROTEIN | | Authors: | Kurinov, I.V, Myers, D.E, Irvin, J.D, Uckun, F.M. | | Deposit date: | 1999-05-05 | | Release date: | 1999-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs.
Protein Sci., 8, 1999
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4C11
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