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5H7C
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BU of 5h7c by Molmil
Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules
Descriptor: Immunoglobulin G-binding protein A, DHR14
Authors:Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
Deposit date:2016-11-17
Release date:2017-06-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
6XI6
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BU of 6xi6 by Molmil
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
Descriptor: helical fusion design
Authors:Bera, A.K, Hsia, Y, Kang, A.S, Shankaran, B, Baker, D.
Deposit date:2020-06-19
Release date:2021-06-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
6XH5
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BU of 6xh5 by Molmil
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
Descriptor: helical fusion design
Authors:Bera, A.K, Hsia, Y, Kang, A.S, Baker, D.
Deposit date:2020-06-18
Release date:2021-06-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
2LXY
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BU of 2lxy by Molmil
NMR structure of 2-MERCAPTOPHENOL-ALPHA3C
Descriptor: 2-MERCAPTOPHENOL, 2-mercaptophenol-alpha3C
Authors:Tommos, C, Valentine, K.G, Martinez-Rivera, M.C, Liang, L, Moorman, V.R.
Deposit date:2012-09-06
Release date:2013-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Reversible phenol oxidation and reduction in the structurally well-defined 2-Mercaptophenol-alpha(3)C protein.
Biochemistry, 52, 2013
6XR2
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BU of 6xr2 by Molmil
Computationally designed right-handed alpha/alpha homotrimeric toroid with 3 repeats per subunit
Descriptor: dTor_3x57R
Authors:Hallinan, J.P, Doyle, L, Bradley, P, Stoddard, B.L.
Deposit date:2020-07-10
Release date:2021-07-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Commun Biol, 4, 2021
6XR1
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BU of 6xr1 by Molmil
Computationally designed right-handed alpha/alpha single-chain toroid with 9 repeats
Descriptor: dTor_9x57R
Authors:Hallinan, J.P, Doyle, L, Bradley, P, Stoddard, B.L.
Deposit date:2020-07-10
Release date:2021-07-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Commun Biol, 4, 2021
5H78
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BU of 5h78 by Molmil
Crystal structure of the PKA-DHR14 fusion protein
Descriptor: cAMP-dependent protein kinase type II-alpha regulatory subunit,DHR14
Authors:Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O.
Deposit date:2016-11-17
Release date:2017-06-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Construction of novel repeat proteins with rigid and predictable structures using a shared helix method.
Sci Rep, 7, 2017
8T6E
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BU of 8t6e by Molmil
Crystal structure of T33-28.3: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles
Descriptor: T33-28.3: A, T33-28.3: B
Authors:Bera, A.K, de Haas, R.J, Kang, A, Sankaran, B, King, N.P.
Deposit date:2023-06-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Rapid and automated design of two-component protein nanomaterials using ProteinMPNN.
Proc.Natl.Acad.Sci.USA, 121, 2024
8T6N
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BU of 8t6n by Molmil
Crystal structure of T33-27.1: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles
Descriptor: T33-27.1 : A, T33-27.1 : B
Authors:Bera, A.K, de Haas, R.J, Kang, A, Sankaran, B, King, N.P.
Deposit date:2023-06-16
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Rapid and automated design of two-component protein nanomaterials using ProteinMPNN.
Proc.Natl.Acad.Sci.USA, 121, 2024
8WAK
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BU of 8wak by Molmil
Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (5.47 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAR
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BU of 8war by Molmil
Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAS
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BU of 8was by Molmil
Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.13 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAP
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BU of 8wap by Molmil
Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (5.85 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAN
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BU of 8wan by Molmil
Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.07 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAL
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BU of 8wal by Molmil
Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (8.52 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAO
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BU of 8wao by Molmil
Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-07
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8WAQ
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BU of 8waq by Molmil
Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS.
Descriptor: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ...
Authors:Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y.
Deposit date:2023-09-08
Release date:2023-12-06
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (6.29 Å)
Cite:Structural visualization of transcription initiation in action.
Science, 382, 2023
8FIQ
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BU of 8fiq by Molmil
Multi-state design of two-state switchable hinge proteins
Descriptor: cs207AB
Authors:Bera, A.K, Leung, P.J.Y, Baker, D.
Deposit date:2022-12-16
Release date:2023-08-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FVT
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BU of 8fvt by Molmil
Multi-state design of two-state switchable hinge proteins
Descriptor: 3hb12
Authors:Bera, A.K, Broerman, A, Baker, D.
Deposit date:2023-01-19
Release date:2023-08-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FIN
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BU of 8fin by Molmil
Multi-state design of two-state switchable hinge proteins
Descriptor: cs207A
Authors:Bera, A.K, Leung, P.J.Y, Baker, D.
Deposit date:2022-12-16
Release date:2023-08-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FIH
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BU of 8fih by Molmil
Multi-state design of two-state switchable hinge proteins
Descriptor: 3hb05, PHOSPHATE ION
Authors:Bera, A.K, Broerman, A, Baker, D.
Deposit date:2022-12-16
Release date:2023-08-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FIT
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BU of 8fit by Molmil
Multi-state design of two-state switchable hinge proteins
Descriptor: cs074A
Authors:Bera, A.K, Praetorius, F, Baker, D.
Deposit date:2022-12-16
Release date:2023-08-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FG6
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BU of 8fg6 by Molmil
Design of amyloidogenic peptide traps
Descriptor: C104.1, amyloidogenic peptide
Authors:Sahtoe, D.D, Bera, A.K, Baker, D.
Deposit date:2022-12-12
Release date:2024-03-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of amyloidogenic peptide traps.
Nat.Chem.Biol., 2024
3DGO
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BU of 3dgo by Molmil
A non-biological ATP binding protein with a Tyr-Phe mutation in the ligand binding domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP Binding Protein-DX, CHLORIDE ION, ...
Authors:Simmons, C.R, Allen, J.P, Chaput, J.C.
Deposit date:2008-06-13
Release date:2009-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A synthetic protein selected for ligand binding affinity mediates ATP hydrolysis.
Acs Chem.Biol., 4, 2009
1ZSZ
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BU of 1zsz by Molmil
Crystal structure of a computationally designed SspB heterodimer
Descriptor: MAGNESIUM ION, Stringent starvation protein B homolog
Authors:Bolon, D.N, Grant, R.A, Baker, T.A, Sauer, R.T.
Deposit date:2005-05-25
Release date:2005-08-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specificity versus stability in computational protein design.
Proc.Natl.Acad.Sci.Usa, 102, 2005

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