7N3C
 
 | | Crystal Structure of Human Fab S24-202 in the complex with the N-terminal Domain of Nucleocapsid protein from SARS CoV-2 | | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, Nucleoprotein, ... | | Authors: | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-05-31 | | Release date: | 2021-07-07 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
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7N3D
 | | Crystal Structure of Human Fab S24-1564 in the complex with the N-terminal Domain of Nucleocapsid protein from SARS CoV-2 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Nucleoprotein, ... | | Authors: | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-05-31 | | Release date: | 2021-07-07 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
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4G1T
 | | Crystal structure of interferon-stimulated gene 54 | | Descriptor: | Interferon-induced protein with tetratricopeptide repeats 2 | | Authors: | Yang, Z, Liang, H, Zhou, Q, Li, Y, Chen, H, Ye, W, Chen, D, Fleming, J, Shu, H, Liu, Y. | | Deposit date: | 2012-07-11 | | Release date: | 2012-08-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms.
Cell Res., 22, 2012
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2ROK
 | | Solution structure of the cap-binding domain of PARN complexed with the cap analog | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, poly(A)-specific ribonuclease | | Authors: | Nagata, T, Suzuki, S, Endo, R, Shirouzu, M, Terada, T, Inoue, M, Kigawa, T, Guntert, P, Hayashizaki, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-03-28 | | Release date: | 2009-02-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition.
Nucleic Acids Res., 36, 2008
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8A3P
 | | Structure of human Fy-5. | | Descriptor: | Glutamine amidotransferase-like class 1 domain-containing protein 1 | | Authors: | Schuhmacher, J.S, Zerial, M. | | Deposit date: | 2022-06-08 | | Release date: | 2022-06-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of mRNA binding by the human FERRY Rab5 effector complex.
Mol.Cell, 83, 2023
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7N6I
 | | ATP-bound TnsC-TniQ complex from ShCAST system | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | | Authors: | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | Deposit date: | 2021-06-08 | | Release date: | 2021-07-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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7YOJ
 | | Structure of CasPi with guide RNA and target DNA | | Descriptor: | CasPi, DNA (30-MER), DNA (5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*CP*CP*AP*G)-3'), ... | | Authors: | Li, C.P, Wang, J, Liu, J.J. | | Deposit date: | 2022-08-01 | | Release date: | 2023-02-15 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | The compact Cas pi (Cas12l) 'bracelet' provides a unique structural platform for DNA manipulation.
Cell Res., 33, 2023
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7DNJ
 | | K63-polyUb MDA5CARDs complex | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, Ubiquitin | | Authors: | Song, B, Chen, Y, Luo, D.H, Zheng, J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
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7DNI
 | | MDA5 CARDs-MAVS CARD polyUb complex | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin | | Authors: | Song, B, Chen, Y, Luo, D.H, Zheng, J. | | Deposit date: | 2020-12-09 | | Release date: | 2021-10-13 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
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5HOH
 | | RIBONUCLEASE T1 (ASN9ALA/THR93ALA DOUBLEMUTANT) COMPLEXED WITH 2'GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | Deposit date: | 1998-09-14 | | Release date: | 1998-09-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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4V4S
 | | Crystal structure of the whole ribosomal complex. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V. | | Deposit date: | 2005-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (6.76 Å) | | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
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2FMR
 | | KH1 FROM THE FRAGILE X PROTEIN FMR1, NMR, 18 STRUCTURES | | Descriptor: | FMR1 PROTEIN | | Authors: | Musco, G, Kharrat, A, Stier, G, Fraternali, F, Gibson, T.J, Nilges, M, Pastore, A. | | Deposit date: | 1997-10-06 | | Release date: | 1998-04-08 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome.
Nat.Struct.Biol., 4, 1997
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4V4T
 | | Crystal structure of the whole ribosomal complex with a stop codon in the A-site. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V. | | Deposit date: | 2005-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (6.46 Å) | | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
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6RNS
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6LKX
 | | The structure of PRRSV helicase | | Descriptor: | CITRIC ACID, GLYCEROL, RNA-dependent RNA polymerase, ... | | Authors: | Shi, Y.J, Tong, X.H, Peng, G.Q. | | Deposit date: | 2019-12-20 | | Release date: | 2020-05-27 | | Last modified: | 2021-06-09 | | Method: | X-RAY DIFFRACTION (2.998 Å) | | Cite: | Structural Characterization of the Helicase nsp10 Encoded by Porcine Reproductive and Respiratory Syndrome Virus.
J.Virol., 94, 2020
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3VRH
 | | Crystal structure of ph0300 | | Descriptor: | BICINE, Putative uncharacterized protein PH0300, ZINC ION | | Authors: | Nakagawa, H, Kuratani, M, Goto-Ito, S, Ito, T, Sekine, S.I, Yokoyama, S. | | Deposit date: | 2012-04-10 | | Release date: | 2013-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic and mutational studies on the tRNA thiouridine synthetase TtuA.
Proteins, 2013
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5VXB
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4V4A
 | | Crystal Structure of the Wild Type Ribosome from E. Coli 70S Ribosome. | | Descriptor: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S ribosomal protein S10, ... | | Authors: | Vila-Sanjurjo, A, Ridgeway, W.K, Seymaner, V, Zhang, W, Santoso, S, Yu, K, Cate, J.H.D. | | Deposit date: | 2003-06-13 | | Release date: | 2014-07-09 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (9.5 Å) | | Cite: | X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli
Proc.Natl.Acad.Sci.USA, 100, 2003
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2RIO
 | | Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation of non-conventional splicing | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, STRONTIUM ION, ... | | Authors: | Lee, K.P, Dey, M, Neculai, D, Cao, C, Dever, T.E, Sicheri, F. | | Deposit date: | 2007-10-12 | | Release date: | 2008-01-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the dual enzyme ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing.
Cell(Cambridge,Mass.), 132, 2008
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7NDH
 | | Crystal structure of ZC3H12C PIN domain | | Descriptor: | 1,2-ETHANEDIOL, Probable ribonuclease ZC3H12C, SODIUM ION | | Authors: | Garg, A, Heinemann, U. | | Deposit date: | 2021-02-01 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
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7NDI
 | | Crystal structure of ZC3H12C PIN domain with Mg2+ Ion | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Probable ribonuclease ZC3H12C, ... | | Authors: | Garg, A, Heinemann, U. | | Deposit date: | 2021-02-01 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.875 Å) | | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
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7NDK
 | | Crystal structure of ZC3H12C PIN catalytic mutant | | Descriptor: | Probable ribonuclease ZC3H12C, SODIUM ION | | Authors: | Garg, A, Heinemann, U. | | Deposit date: | 2021-02-01 | | Release date: | 2021-05-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Nucleic Acids Res., 49, 2021
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7Z2J
 | | White Bream virus N7-Methyltransferase | | Descriptor: | Non-structural protein 1, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Shannon, A, Gauffre, P, Canard, B, Ferron, F. | | Deposit date: | 2022-02-28 | | Release date: | 2022-11-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.657 Å) | | Cite: | A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.
Nucleic Acids Res., 50, 2022
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4P8Z
 | | Speciation of a group I intron into a lariat capping ribozyme | | Descriptor: | Didymium iridis partial IGS, 18S rRNA gene, I-DirI gene and partial ITS1 | | Authors: | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | | Deposit date: | 2014-04-01 | | Release date: | 2014-05-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.85 Å) | | Cite: | Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4FXW
 | | Structure of phosphorylated SF1 complex with U2AF65-UHM domain | | Descriptor: | SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit | | Authors: | Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. | | Deposit date: | 2012-07-03 | | Release date: | 2013-01-16 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.
Structure, 21, 2013
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