1IJX
 
 | | CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB) | | Descriptor: | SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3, SULFATE ION | | Authors: | Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J. | | Deposit date: | 2001-04-30 | | Release date: | 2001-07-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature, 412, 2001
|
|
1IJY
 | | CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MOUSE FRIZZLED 8 (MFZ8) | | Descriptor: | FRIZZLED HOMOLOG 8 | | Authors: | Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J. | | Deposit date: | 2001-05-01 | | Release date: | 2001-07-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature, 412, 2001
|
|
5Z5C
 | | Crystal structure of hydrogen sulfide-producing enzyme (Fn1055) from Fusobacterium nucleatum: lysine-dimethylated form | | Descriptor: | CHLORIDE ION, Cysteine synthase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Kezuka, Y, Yoshida, Y, Nonaka, T. | | Deposit date: | 2018-01-17 | | Release date: | 2018-02-14 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen sulfide-producing oral pathogen,
Biochem. J., 475, 2018
|
|
4ZM8
 | | Crystal Structure of Sialostatin L | | Descriptor: | Putative secreted cystatin | | Authors: | Andersen, J.F, Kosyfakis, M. | | Deposit date: | 2015-05-02 | | Release date: | 2015-06-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6762 Å) | | Cite: | The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model.
Mol. Microbiol., 77, 2010
|
|
1GLO
 | | Crystal Structure of Cys25Ser mutant of human cathepsin S | | Descriptor: | CATHEPSIN S | | Authors: | Turkenburg, J.P, Lamers, M.B.A.C, Brzozowski, A.M, Wright, L.M, Hubbard, R.E, Sturt, S.L, Williams, D.H. | | Deposit date: | 2001-08-31 | | Release date: | 2002-08-29 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a Cys25->Ser Mutant of Human Cathepsin Cathepsin S
Acta Crystallogr.,Sect.D, 58, 2002
|
|
5B55
 | | Crystal structure of hydrogen sulfide-producing enzyme (Fn1055) D232N mutant in complexed with alpha-aminoacrylate intermediate: lysine-dimethylated form | | Descriptor: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Cysteine synthase, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kezuka, Y, Yoshida, Y, Nonaka, T. | | Deposit date: | 2016-04-22 | | Release date: | 2017-04-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen sulfide-producing oral pathogen,Fusobacterium nucleatum.
Biochem. J., 475, 2018
|
|
8RBL
 | | Crystal structure of Mycobacterium tuberculosis MmaA1 with S-adenosyl homocysteine | | Descriptor: | 1,2-ETHANEDIOL, Mycolic acid methyltransferase MmaA1, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Kobakhidze, G, Wachelder, L, Chaudhary, B, Mazumdar, P.A, Madhurantakam, C, Dong, G. | | Deposit date: | 2023-12-04 | | Release date: | 2024-12-11 | | Last modified: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structures of the mycolic acid methyl transferase 1 (MmaA1) from Mycobacterium tuberculosis in the apo-form and in complex with different cofactors reveal unique features for substrate binding.
J.Biomol.Struct.Dyn., 2025
|
|
3HKL
 | | Crystal Structure of the Frizzled-like Cysteine-rich Domain of MuSK | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Muscle, skeletal receptor tyrosine protein kinase | | Authors: | Stiegler, A.L, Hubbard, S.R. | | Deposit date: | 2009-05-24 | | Release date: | 2009-08-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK.
J.Mol.Biol., 393, 2009
|
|
3FWJ
 | | Ferric camphor bound Cytochrome P450cam containing a selenocysteine as the 5th heme ligand, orthorombic crystal form | | Descriptor: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | Authors: | Schlichting, I, von Koenig, K, Aldag, C, Hilvert, D. | | Deposit date: | 2009-01-18 | | Release date: | 2009-03-03 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3FWI
 | | Ferric camphor bound Cytochrome P450cam containing a selenocysteine as the 5th heme ligand, tetragonal crystal form | | Descriptor: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | Authors: | Schlichting, I, von Koenig, K, Aldag, C, Hilvert, D. | | Deposit date: | 2009-01-18 | | Release date: | 2009-03-03 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3PS8
 | | Crystal structure of L68V mutant of human cystatin C | | Descriptor: | ACETATE ION, Cystatin-C, DI(HYDROXYETHYL)ETHER | | Authors: | Orlikowska, M, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | | Deposit date: | 2010-12-01 | | Release date: | 2011-12-21 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of L68V mutant of human cystatin C
To be Published
|
|
4WZ6
 | | Human CFTR aa389-678 (NBD1), deltaF508 with three solubilizing mutations, bound ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | | Authors: | Byrnes, L.J, Hall, J. | | Deposit date: | 2014-11-18 | | Release date: | 2015-11-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy.
Protein Sci., 25, 2016
|
|
1EV8
 | | CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI | | Descriptor: | THYMIDYLATE SYNTHASE | | Authors: | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | | Deposit date: | 2000-04-19 | | Release date: | 2000-05-03 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
|
|
7EDZ
 | | Crystal Structure of human PPCS in complex with P-HoPan and AMPPNP | | Descriptor: | 4-[[(2R)-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]butanoic acid, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Sharma, N, Mostert, K.J, Strauss, E, Anand, R. | | Deposit date: | 2021-03-17 | | Release date: | 2021-11-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity.
Acs Chem.Biol., 16, 2021
|
|
3C64
 | | The MC179 portion of the Cysteine-rich Interdomain Region (CIDR) of a Plasmodium falciparum Erythrocyte Membrane Protein-1 (PfEMP1) | | Descriptor: | CHLORIDE ION, PfEMP1 variant 2 of strain MC, TETRAETHYLENE GLYCOL | | Authors: | Klein, M.M, Gittis, A.G, Su, H.P, Makobongo, M.O, Moore, J.M, Singh, S, Miller, L.H, Garboczi, D.N. | | Deposit date: | 2008-02-02 | | Release date: | 2008-09-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure.
Plos Pathog., 4, 2008
|
|
1IJN
 | | Crystal structure of the transthyretin mutant TTR C10A/Y114C | | Descriptor: | BETA-MERCAPTOETHANOL, TRANSTHYRETIN | | Authors: | Eneqvist, T, Karlsson, A, Olofsson, A, Sauer-Eriksson, A.E. | | Deposit date: | 2001-04-27 | | Release date: | 2003-06-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Cys114-linked dimers of transthyretin are compatible with amyloid formation
Biochemistry, 44, 2005
|
|
1EVF
 | | CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI | | Descriptor: | SULFATE ION, THYMIDYLATE SYNTHASE | | Authors: | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | | Deposit date: | 2000-04-19 | | Release date: | 2000-05-03 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
|
|
3VV5
 | | Crystal structure of TTC0807 complexed with (S)-2-aminoethyl-L-cysteine (AEC) | | Descriptor: | Amino acid ABC transporter, binding protein, L-THIALYSINE, ... | | Authors: | Tomita, T, Kanemaru, Y, Hasebe, F, Kuzuyama, T, Nishiyama, M. | | Deposit date: | 2012-07-16 | | Release date: | 2013-06-26 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Two ATP-Binding Cassette Transporters Involved in (S)-2-Aminoethyl-Cysteine Uptake in Thermus thermophilus
J.Bacteriol., 195, 2013
|
|
2R5C
 | | Aedes Kynurenine Aminotransferase in Complex with Cysteine | | Descriptor: | Kynurenine aminotransferase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | | Authors: | Han, Q, Gao, Y.G, Robinson, H, Li, J. | | Deposit date: | 2007-09-03 | | Release date: | 2008-03-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase.
Biochemistry, 47, 2008
|
|
2BU9
 | | Isopenicillin N synthase complexed with L-aminoadipoyl-L-cysteinyl-L- hexafluorovaline | | Descriptor: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-L-3,3,3,3',3',3'-HEXAFLUOROVALINE, FE (III) ION, ISOPENICILLIN N SYNTHETASE, ... | | Authors: | Howard-Jones, A.R, Rutledge, P.J, Clifton, I.J, Adlington, R.M, Baldwin, J.E. | | Deposit date: | 2005-06-09 | | Release date: | 2005-09-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Unique Binding of a Non-Natural L,L,L-Substrate by Isopenicillin N Synthase
Biochem.Biophys.Res.Commun., 336, 2005
|
|
3CYF
 | | Crystal Structure of E18N DJ-1 | | Descriptor: | Protein DJ-1 | | Authors: | Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. | | Deposit date: | 2008-04-25 | | Release date: | 2008-07-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Biochemistry, 47, 2008
|
|
3SOD
 | | CHANGES IN CRYSTALLOGRAPHIC STRUCTURE AND THERMOSTABILITY OF A CU,ZN SUPEROXIDE DISMUTASE MUTANT RESULTING FROM THE REMOVAL OF BURIED CYSTEINE | | Descriptor: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | Authors: | Mcree, D.E, Redford, S.M, Getzoff, E.D, Lepock, J.R, Hallewell, R.A, Tainer, J.A. | | Deposit date: | 1990-06-26 | | Release date: | 1993-04-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine.
J.Biol.Chem., 265, 1990
|
|
1H9C
 | | NMR structure of cysteinyl-phosphorylated enzyme IIB of the N,N'-diacetylchitobiose specific phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli. | | Descriptor: | PTS SYSTEM, CHITOBIOSE-SPECIFIC IIB COMPONENT | | Authors: | Ab, E, Schuurman-Wolters, G.K, Nijlant, D, Dijkstra, K, Saier, M.H, Robillard, G.T, Scheek, R.M. | | Deposit date: | 2001-03-07 | | Release date: | 2001-05-21 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of Cysteinyl-Phosphorylated Enzyme Iib of the N,N'-Diacetylchitobiose Specific Phosphoenolpyruvate-Dependentphosphotransferase System of Escherichia Coli
J.Mol.Biol., 308, 2001
|
|
1HP8
 | | SOLUTION STRUCTURE OF HUMAN P8-MTCP1, A CYSTEINE-RICH PROTEIN ENCODED BY THE MTCP1 ONCOGENE,REVEALS A NEW ALPHA-HELICAL ASSEMBLY MOTIF, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | Cx9C motif-containing protein 4 | | Authors: | Barthe, P, Chiche, L, Strub, M.P, Roumestand, C. | | Deposit date: | 1997-08-26 | | Release date: | 1998-03-04 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Solution structure of human p8MTCP1, a cysteine-rich protein encoded by the MTCP1 oncogene, reveals a new alpha-helical assembly motif.
J.Mol.Biol., 274, 1997
|
|
2JA4
 | | Crystal structure of CD5 domain III reveals the fold of a group B scavenger cysteine-rich receptor | | Descriptor: | T-CELL SURFACE GLYCOPROTEIN CD5 | | Authors: | Rodamilans, B, Munoz, I.G, Sarrias, M.R, Lozano, F, Blanco, F.J, Montoya, G. | | Deposit date: | 2006-11-21 | | Release date: | 2007-03-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal Structure of the Third Extracellular Domain of Cd5 Reveals the Fold of a Group B Scavenger Cysteine-Rich Receptor Domain.
J.Biol.Chem., 282, 2007
|
|
