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2ESO
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BU of 2eso by Molmil
Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b mutant Ile37Ala
Descriptor: Ubiquitin-conjugating enzyme E2 D2
Authors:Ozkan, E, Yu, H, Deisenhofer, J.
Deposit date:2005-10-26
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases
Proc.Natl.Acad.Sci.Usa, 102, 2005
2ESP
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BU of 2esp by Molmil
Human ubiquitin-conjugating enzyme (E2) UbcH5b mutant Ile88Ala
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Ubiquitin-conjugating enzyme E2 D2
Authors:Ozkan, E, Yu, H, Deisenhofer, J.
Deposit date:2005-10-26
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases
Proc.Natl.Acad.Sci.Usa, 102, 2005
1WZW
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BU of 1wzw by Molmil
Crystal Structure of UbcH8
Descriptor: Ubiquitin-conjugating enzyme E2 L6
Authors:Mizushima, T, Suzuki, M, Teshima, N, Yamane, T, Murata, S, Tanaka, K.
Deposit date:2005-03-10
Release date:2005-03-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of UbcH8
To be Published
1YRV
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BU of 1yrv by Molmil
Novel Ubiquitin-Conjugating Enzyme
Descriptor: ubiquitin-conjugating ligase MGC351130
Authors:Walker, J.R, Choe, J, Avvakumov, G.V, Newman, E.M, MacKenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-02-04
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1Z2U
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BU of 1z2u by Molmil
The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
Descriptor: (R,R)-2,3-BUTANEDIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Gavira, J.A, DiGiamamarino, E, Tempel, W, Liu, Z.J, Wang, B.C, Meehan, E, Ng, J.D, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-03-09
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance
To be published
1ZDN
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BU of 1zdn by Molmil
Ubiquitin-conjugating enzyme E2S
Descriptor: SODIUM ION, Ubiquitin-conjugating enzyme E2S
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-04-14
Release date:2005-05-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1Z3D
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BU of 1z3d by Molmil
Protein crystal growth improvement leading to the 2.5A crystallographic structure of ubiquitin-conjugating enzyme (ubc-1) from Caenorhabditis elegans
Descriptor: Ubiquitin-conjugating enzyme E2 1
Authors:Gavira, J.A, DiGiammarino, E, Tempel, W, Toh, D, Liu, Z.J, Wang, B.C, Meehan, E, Ng, J.D, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-03-11
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Protein crystal growth improvement leading to the 2.5A crystallographic structure of ubiquitin-conjugating enzyme (ubc-1) from Caenorhabditis elegans
To be Published
1ZUO
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BU of 1zuo by Molmil
Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in Embryo Attachment and Implantation
Descriptor: BETA-MERCAPTOETHANOL, Hypothetical protein LOC92912
Authors:Walker, J.R, Avvakumov, G.V, Cui, H, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-05-31
Release date:2005-07-05
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1YH2
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BU of 1yh2 by Molmil
Ubiquitin-Conjugating Enzyme HSPC150
Descriptor: HSPC150 protein similar to ubiquitin-conjugating enzyme
Authors:Walker, J.R, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-01-06
Release date:2005-02-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2A7L
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BU of 2a7l by Molmil
Structure of the human hypothetical ubiquitin-conjugating enzyme, LOC55284
Descriptor: Hypothetical ubiquitin-conjugating enzyme LOC55284, SODIUM ION
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-07-05
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1Y6L
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BU of 1y6l by Molmil
Human ubiquitin conjugating enzyme E2E2
Descriptor: Ubiquitin-conjugating enzyme E2E2
Authors:Walker, J.R, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2004-12-06
Release date:2005-01-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1YF9
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BU of 1yf9 by Molmil
Structural analysis of Leishmania major ubiquitin conjugating enzyme E2
Descriptor: CHLORIDE ION, Ubiquitin carrier protein 4
Authors:Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-12-31
Release date:2005-02-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Leishmania major ubiquitin conjugating enzyme E2
To be Published
2A4D
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BU of 2a4d by Molmil
Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1)
Descriptor: Ubiquitin-conjugating enzyme E2 variant 1
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-06-28
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2AAK
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BU of 2aak by Molmil
UBIQUITIN CONJUGATING ENZYME FROM ARABIDOPSIS THALIANA
Descriptor: UBIQUITIN CONJUGATING ENZYME
Authors:Cook, W.J, Jeffrey, L.C, Sullivan, M.L, Vierstra, R.D.
Deposit date:1997-11-06
Release date:1998-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of a ubiquitin-conjugating enzyme (E2).
J.Biol.Chem., 267, 1992
8IYA
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BU of 8iya by Molmil
Complex of SETDB1-derived peptide bound to UBE2E1
Descriptor: Histone-lysine N-methyltransferase SETDB1, SULFATE ION, Ubiquitin-conjugating enzyme E2 E1
Authors:Du, Y.X, Liu, L.
Deposit date:2023-04-04
Release date:2024-01-03
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Complex of SETDB1-derived peptide bound to UBE2E1
To Be Published
8JVD
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BU of 8jvd by Molmil
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening
Descriptor: 5-fluoranyl-1,3-benzoxazol-2-amine, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-28
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening.
Protein Sci., 33, 2024
8JUC
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BU of 8juc by Molmil
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening
Descriptor: 1,2-ETHANEDIOL, 7-methyl-2-(trifluoromethyl)-3~{H}-[1,2,4]triazolo[1,5-a]pyridin-5-one, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-26
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening.
Protein Sci., 33, 2024
5EGG
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BU of 5egg by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UBCH5C
Descriptor: Ubiquitin-conjugating enzyme E2 D3
Authors:Zhu, L, Li, H, Wu, F, Zhu, J.
Deposit date:2015-10-27
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
Acta Pharm Sin B, 7, 2017
8JVE
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BU of 8jve by Molmil
Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer
Descriptor: 1,2-ETHANEDIOL, 1-(3-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-28
Release date:2023-11-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer.
Biochem.Biophys.Res.Commun., 689, 2023
8JVL
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BU of 8jvl by Molmil
Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer
Descriptor: 1,2-ETHANEDIOL, 1-(4-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-28
Release date:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer.
Biochem.Biophys.Res.Commun., 689, 2023
5F6D
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BU of 5f6d by Molmil
Crystal structure of Ubc9 (K48A/K49A/E54A) complexed with Fragment 6
Descriptor: 6~{H}-benzo[c][1,2]benzothiazine 5,5-dioxide, SUMO-conjugating enzyme UBC9
Authors:Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S.
Deposit date:2015-12-05
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F6W
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BU of 5f6w by Molmil
Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 1 (biphenol)
Descriptor: 2-(2-hydroxyphenyl)phenol, SUMO-conjugating enzyme UBC9
Authors:Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S.
Deposit date:2015-12-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F6V
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BU of 5f6v by Molmil
Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 1 (biphenol from fragment cocktail screen)
Descriptor: 2-(2-hydroxyphenyl)phenol, SUMO-conjugating enzyme UBC9
Authors:Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S.
Deposit date:2015-12-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F6E
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BU of 5f6e by Molmil
Crystal Structure of human Ubc9 (K48A/K49A/E54A)
Descriptor: 1,2-ETHANEDIOL, SUMO-conjugating enzyme UBC9
Authors:Lountos, G.T, Hewitt, W.M, Zlotkowski, Z, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S.
Deposit date:2015-12-05
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F6U
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BU of 5f6u by Molmil
Crystal Structure of Ubc9 (K48A/K49A/E54A) complexed with Fragment 8 (JSS190B146)
Descriptor: SUMO-conjugating enzyme UBC9, ethyl 3-[4-(2-hydroxyphenyl)-3-oxidanyl-phenyl]propanoate
Authors:Lountos, G.T, Hewitt, W.M, Zlotkowski, Z, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S.
Deposit date:2015-12-07
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016

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