6SGC
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![BU of 6sgc by Molmil](/molmil-images/mine/6sgc) | Rabbit 80S ribosome stalled on a poly(A) tail | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2019-08-03 | Release date: | 2019-12-04 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of ribosome stalling during translation of a poly(A) tail. Nat.Struct.Mol.Biol., 26, 2019
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6SWD
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![BU of 6swd by Molmil](/molmil-images/mine/6swd) | IC2 body model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Coureux, P.-D, Mechulam, Y, Schmitt, E. | Deposit date: | 2019-09-20 | Release date: | 2020-02-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
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6T0B
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![BU of 6t0b by Molmil](/molmil-images/mine/6t0b) | The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ... | Authors: | Marechal, A, Pinotsis, N, Hartley, A. | Deposit date: | 2019-10-02 | Release date: | 2020-04-22 | Last modified: | 2020-05-06 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SZS
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![BU of 6szs by Molmil](/molmil-images/mine/6szs) | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Muller, C, Beckert, B, Wilson, D.N. | Deposit date: | 2019-10-02 | Release date: | 2019-12-04 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis. Nat Commun, 10, 2019
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6T5J
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![BU of 6t5j by Molmil](/molmil-images/mine/6t5j) | Structure of NUDT15 in complex with inhibitor TH1760 | Descriptor: | 6-[4-(1~{H}-indol-5-ylcarbonyl)piperazin-1-yl]sulfonyl-3~{H}-1,3-benzoxazol-2-one, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Carter, M, Rehling, D, Desroses, M, Zhang, S.M, Hagenkort, A, Valerie, N.C.K, Helleday, T, Stenmark, P. | Deposit date: | 2019-10-16 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Development of a chemical probe against NUDT15. Nat.Chem.Biol., 16, 2020
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5MGP
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![BU of 5mgp by Molmil](/molmil-images/mine/5mgp) | Structural basis for ArfA-RF2 mediated translation termination on stop-codon lacking mRNAs | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Huter, P, Mueller, C, Beckert, B, Arenz, S, Berninghausen, O, Beckmann, R, Wilson, N.D. | Deposit date: | 2016-11-21 | Release date: | 2016-12-14 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons. Nature, 541, 2017
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6T83
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![BU of 6t83 by Molmil](/molmil-images/mine/6t83) | Structure of yeast disome (di-ribosome) stalled on poly(A) tract. | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-24 | Release date: | 2019-12-25 | Last modified: | 2020-02-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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6UCQ
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![BU of 6ucq by Molmil](/molmil-images/mine/6ucq) | Crystal structure of the Thermus thermophilus 70S ribosome recycling complex | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J. | Deposit date: | 2019-09-17 | Release date: | 2019-12-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for ribosome recycling by RRF and tRNA. Nat.Struct.Mol.Biol., 27, 2020
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6B4V
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6UGM
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![BU of 6ugm by Molmil](/molmil-images/mine/6ugm) | Structural basis of COMPASS eCM recognition of an unmodified nucleosome | Descriptor: | Bre2, DNA (146-MER), H3 N-terminus, ... | Authors: | Hsu, P.L, Shi, H, Zheng, N. | Deposit date: | 2019-09-26 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS. Mol.Cell, 76, 2019
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6AVO
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![BU of 6avo by Molmil](/molmil-images/mine/6avo) | Cryo-EM structure of human immunoproteasome with a novel noncompetitive inhibitor that selectively inhibits activated lymphocytes | Descriptor: | N~1~-{2-[([1,1'-biphenyl]-3-carbonyl)amino]ethyl}-N~4~-tert-butyl-N~2~-(3-phenylpropanoyl)-L-aspartamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | Authors: | Li, H, Santos, R, Bai, L. | Deposit date: | 2017-09-04 | Release date: | 2017-12-06 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes. Nat Commun, 8, 2017
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5OE3
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![BU of 5oe3 by Molmil](/molmil-images/mine/5oe3) | Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 1) | Descriptor: | 1,2-ETHANEDIOL, 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, ACETATE ION, ... | Authors: | Witzgall, F, Ewert, W, Blankenfeldt, W. | Deposit date: | 2017-07-07 | Release date: | 2017-09-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis. Chembiochem, 18, 2017
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5Z3G
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![BU of 5z3g by Molmil](/molmil-images/mine/5z3g) | Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | Authors: | Zhu, X, Zhou, D, Ye, K. | Deposit date: | 2018-01-06 | Release date: | 2018-04-11 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell, 10, 2019
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2C12
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![BU of 2c12 by Molmil](/molmil-images/mine/2c12) | Crystal Structure of Nitroalkane Oxidase in Complex with Spermine, a Competitive Inhibitor | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Nagpal, A, Valley, M.P, Fitzpatrick, P.F, Orville, A.M. | Deposit date: | 2005-09-10 | Release date: | 2006-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal Structures of Nitroalkane Oxidase: Insights Into the Reaction Mechanism from a Covalent Complex of the Flavoenzyme Trapped During Turnover. Biochemistry, 45, 2006
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5OA3
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![BU of 5oa3 by Molmil](/molmil-images/mine/5oa3) | Human 40S-eIF2D-re-initiation complex | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N. | Deposit date: | 2017-06-20 | Release date: | 2017-08-09 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural and Functional Insights into Human Re-initiation Complexes. Mol. Cell, 67, 2017
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5MKI
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![BU of 5mki by Molmil](/molmil-images/mine/5mki) | |
5MLC
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![BU of 5mlc by Molmil](/molmil-images/mine/5mlc) | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions | Descriptor: | 23S ribosomal RNA, chloroplastic, 4.8S ribosomal RNA, ... | Authors: | Graf, M, Arenz, S, Huter, P, Doenhoefer, A, Novacek, J, Wilson, D.N. | Deposit date: | 2016-12-06 | Release date: | 2016-12-28 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. Nucleic Acids Res., 45, 2017
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6TC3
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![BU of 6tc3 by Molmil](/molmil-images/mine/6tc3) | |
6TBV
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![BU of 6tbv by Molmil](/molmil-images/mine/6tbv) | |
6B0Q
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![BU of 6b0q by Molmil](/molmil-images/mine/6b0q) | Zinc finger Domain of WT1(-KTS form) with 13+1mer Oligonucleotide with 3' Triplet TGT | Descriptor: | DNA (5'-D(P*AP*AP*CP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*GP*GP*AP*GP*TP*GP*TP*T)-3'), SULFATE ION, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2017-09-14 | Release date: | 2018-01-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. Nucleic Acids Res., 46, 2018
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6UO1
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![BU of 6uo1 by Molmil](/molmil-images/mine/6uo1) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA (containing pseudouridine at the first position of the codon) and deacylated A-, P-, and E-site tRNAs at 2.95A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Batool, Z, Dobosz-Bartoszek, M, Polikanov, Y.S. | Deposit date: | 2019-10-14 | Release date: | 2019-11-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Pseudouridinylation of mRNA coding sequences alters translation. Proc.Natl.Acad.Sci.USA, 116, 2019
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6T7I
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![BU of 6t7i by Molmil](/molmil-images/mine/6t7i) | Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | Deposit date: | 2019-10-22 | Release date: | 2019-12-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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5OMX
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5ZLU
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![BU of 5zlu by Molmil](/molmil-images/mine/5zlu) | Ribosome Structure bound to ABC-F protein. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Su, W.X, Kumar, V, Ero, R, Andrew, S.W.W, Jian, S, Yong-Gui, G. | Deposit date: | 2018-03-29 | Release date: | 2018-08-01 | Last modified: | 2019-12-04 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ribosome protection by antibiotic resistance ATP-binding cassette protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2CCX
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![BU of 2ccx by Molmil](/molmil-images/mine/2ccx) | |