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3GJ7
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BU of 3gj7 by Molmil
Crystal structure of human RanGDP-Nup153ZnF12 complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Partridge, J.R, Schwartz, T.U.
Deposit date:2009-03-07
Release date:2009-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain.
J.Mol.Biol., 391, 2009
6Z1N
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BU of 6z1n by Molmil
Structure of the human heterotetrameric cis-prenyltransferase complex
Descriptor: Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, FARNESYL DIPHOSPHATE, ...
Authors:Lisnyansky Bar-El, M, Haitin, Y, Giladi, M.
Deposit date:2020-05-14
Release date:2020-10-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex.
Nat Commun, 11, 2020
7A94
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BU of 7a94 by Molmil
SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Benton, D.J, Wrobel, A.G, Rosenthal, P.B, Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 588, 2020
6ZNN
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BU of 6znn by Molmil
The pointed end complex of dynactin bound to Hook3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ...
Authors:Lau, C.K, Lacey, S.E, Carter, A.P.
Deposit date:2020-07-06
Release date:2020-07-29
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM reveals the complex architecture of dynactin's shoulder region and pointed end.
Embo J., 40, 2021
4M63
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BU of 4m63 by Molmil
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Tomchick, D.R, Zahm, J.A, Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
6YSS
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BU of 6yss by Molmil
Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
3FTW
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BU of 3ftw by Molmil
Leukotriene A4 hydrolase in complex with fragments N-(pyridin-3-ylmethyl)aniline and acetate
Descriptor: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
Authors:Davies, D.R.
Deposit date:2009-01-13
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
4GOO
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BU of 4goo by Molmil
Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Benzothiophene Aza-SAM
Descriptor: 5'-{[(3S)-3-amino-3-carboxypropyl][2-(1-benzothiophen-3-yl)ethyl]amino}-5'-deoxyadenosine, DNA adenine methylase
Authors:Harmer, J.E, Roach, P.L.
Deposit date:2012-08-20
Release date:2014-02-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Selective N-6 adenine methyltransferase Inhibition by Transition State Mimic
To be published
3FUD
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BU of 3fud by Molmil
Leukotriene A4 hydrolase in complex with N-methyl-1-(2-thiophen-2-ylphenyl)methanamine
Descriptor: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
Authors:Davies, D.R.
Deposit date:2009-01-14
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
6NTK
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BU of 6ntk by Molmil
Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by A-232
Descriptor: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bester, S.M, Guelta, M.A, Height, J.J, Pegan, S.D.
Deposit date:2019-01-29
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Insights into inhibition of human acetylcholinesterase by Novichok, A-series Nerve Agents
To Be Published
6ZP1
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BU of 6zp1 by Molmil
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6O2T
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BU of 6o2t by Molmil
Acetylated Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E.
Deposit date:2019-02-24
Release date:2019-05-22
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
6NUF
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BU of 6nuf by Molmil
Structure of Calcineurin in complex with NHE1 peptide
Descriptor: CALCIUM ION, Calcineurin subunit B type 1, DI(HYDROXYETHYL)ETHER, ...
Authors:Wang, X, Page, R, Peti, W.
Deposit date:2019-01-31
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.
Nat Commun, 10, 2019
6ZHW
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BU of 6zhw by Molmil
Ultrafast Structural Response to Charge Redistribution Within a Photosynthetic Reaction Centre - 1 ps structure
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Baath, P, Dods, R, Branden, G, Neutze, R.
Deposit date:2020-06-23
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ultrafast structural changes within a photosynthetic reaction centre.
Nature, 589, 2021
4H0X
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BU of 4h0x by Molmil
Crystal structure of NAD+-Ia(E380A)-actin complex
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Tsurumura, T, Oda, M, Nagahama, M, Tsuge, H.
Deposit date:2012-09-10
Release date:2013-02-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
Proc.Natl.Acad.Sci.USA, 110, 2013
6ZI6
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BU of 6zi6 by Molmil
Ultrafast Structural Response to Charge Redistribution Within a Photosynthetic Reaction Centre - 20 ps structure
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Baath, P, Dods, R, Braenden, G, Neutze, R.
Deposit date:2020-06-24
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ultrafast structural changes within a photosynthetic reaction centre.
Nature, 589, 2021
4GST
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BU of 4gst by Molmil
REACTION COORDINATE MOTION IN AN SNAR REACTION CATALYZED BY GLUTATHIONE TRANSFERASE
Descriptor: 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION
Authors:Ji, X, Armstrong, R.N, Gilliland, G.L.
Deposit date:1993-07-20
Release date:1993-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase.
Biochemistry, 32, 1993
6ZR2
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BU of 6zr2 by Molmil
Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J.
Deposit date:2020-07-10
Release date:2020-10-21
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
6YHS
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BU of 6yhs by Molmil
Acinetobacter baumannii ribosome-amikacin complex - 50S subunit
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A.
Deposit date:2020-03-30
Release date:2020-09-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Structure, 28, 2020
7BL6
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BU of 7bl6 by Molmil
50S-ObgE-GMPPNP particle
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T.
Deposit date:2021-01-18
Release date:2021-05-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
7BL5
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BU of 7bl5 by Molmil
pre-50S-ObgE particle
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Hilal, T, Nikolay, R, Spahn, C.M.T, Schmidt, S.
Deposit date:2021-01-18
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
4GWG
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BU of 4gwg by Molmil
Crystal Structure Analysis of 6-phosphogluconate dehydrogenase apo-form
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating
Authors:He, C, Zhou, L, Zhang, L.
Deposit date:2012-09-03
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3907 Å)
Cite:Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer Cell, 22, 2012
4GWT
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BU of 4gwt by Molmil
Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid
Descriptor: (2S)-2-hydroxybutanedioic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T.
Deposit date:2012-09-03
Release date:2013-10-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
6NPH
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BU of 6nph by Molmil
Structure of NKCC1 TM domain
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
Authors:Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
Deposit date:2019-01-17
Release date:2019-07-31
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
7C26
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BU of 7c26 by Molmil
Glycosidase Wild Type at pH4.5
Descriptor: AMMONIUM ION, CITRIC ACID, GLYCEROL, ...
Authors:Tagami, T, Kikuchi, A, Okuyama, M, Kimura, A.
Deposit date:2020-05-07
Release date:2021-05-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022

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