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4OFE	Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis Descriptor: 12-mer DNA(G), 12-mer DNA(T), MAGNESIUM ION, ... Authors: Ouzon-Shubeita, H, Lin, Y.-L, Lee, S. Deposit date: 2014-01-14 Release date: 2015-04-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure of R468K/D560N MBD4 bound to G:T mispair DNA To be Published
3QF3	Crystal structure of EspR transcription factor from mycobacterium tuberculosis Descriptor: (2S)-2-hydroxybutanedioic acid, D-MALATE, ESX-1 secretion-associated regulator EspR Authors: Blasco, B, Pojer, F, Cole, S.T. Deposit date: 2011-01-21 Release date: 2011-09-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis. Mol.Microbiol., 82, 2011
4NJ5	Crystal structure of SUVH9 Descriptor: Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9, ZINC ION Authors: Du, J, Patel, D.J. Deposit date: 2013-11-08 Release date: 2014-01-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation. Nature, 507, 2014
7R8J	Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' p guide DNA in the presence of Mg2+ Descriptor: Argonaute, DNA (5'-D(*TP*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A)-3') Authors: Shin, Y, Murakami, K.S. Deposit date: 2021-06-26 Release date: 2022-07-06 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. Nat Commun, 13, 2022
7R8G	Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' OH guide DNA Descriptor: Argonaute, DNA (5'-D(*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A)-3') Authors: Shin, Y, Murakami, K.S. Deposit date: 2021-06-26 Release date: 2022-07-06 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. Nat Commun, 13, 2022
7R8H	Crystal structure of Pseudooceanicola lipolyticus Argonaute bound to 5' p guide DNA Descriptor: Argonaute, DNA (5'-D(*TP*TP*AP*CP*TP*GP*CP*AP*CP*AP*GP*GP*TP*GP*AP*CP*GP*A)-3') Authors: Shin, Y, Murakami, K.S. Deposit date: 2021-06-26 Release date: 2022-07-06 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity. Nat Commun, 13, 2022
2ME0	NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG Descriptor: Homeobox protein GBX-1 Authors: Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) Deposit date: 2013-09-20 Release date: 2013-10-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens solved in the presence of the DNA sequence CGACTAATTAGTCG To be Published
1Z5Z	Sulfolobus solfataricus SWI2/SNF2 ATPase C-terminal domain Descriptor: Helicase of the snf2/rad54 family Authors: Duerr, H, Koerner, C, Mueller, M, Hickmann, V, Hopfner, K.P. Deposit date: 2005-03-21 Release date: 2005-05-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA Cell(Cambridge,Mass.), 121, 2005
4DDT	Thermotoga maritima reverse gyrase, C2 FORM 2 Descriptor: Reverse gyrase, ZINC ION Authors: Rudolph, M.G, Klostermeier, D. Deposit date: 2012-01-19 Release date: 2012-12-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling. Nucleic Acids Res., 41, 2013
4DDV	Thermotoga maritima reverse gyrase, triclinic form Descriptor: Reverse gyrase, ZINC ION Authors: Rudolph, M.G, Klostermeier, D. Deposit date: 2012-01-19 Release date: 2012-12-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.46 Å) Cite: Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling. Nucleic Acids Res., 41, 2013
5M31	Macrodomain of Thermus aquaticus DarG Descriptor: Appr-1-p processing domain protein, CHLORIDE ION, GLYCEROL Authors: Ariza, A. Deposit date: 2016-10-13 Release date: 2016-12-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.67 Å) Cite: The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA. Mol. Cell, 64, 2016
4FHC	Spore photoproduct lyase Descriptor: 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, SULFATE ION, ... Authors: Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. Deposit date: 2012-06-06 Release date: 2012-07-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res., 40, 2012
5WQV	Crystal structure of PriB mutant - S55A Descriptor: Primosomal replication protein N Authors: Fujiyama, S, Shiroishi, M, Katayama, T, Abe, Y, Ueda, T. Deposit date: 2016-11-28 Release date: 2017-11-29 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Insight into the interaction between PriB and DnaT on bacterial DNA replication restart: Significance of the residues on PriB dimer interface and highly acidic region on DnaT. Biochim Biophys Acta Proteins Proteom, 1867, 2019
4FHE	Spore photoproduct lyase C140A mutant Descriptor: 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, SULFATE ION, ... Authors: Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. Deposit date: 2012-06-06 Release date: 2012-07-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res., 40, 2012
5OHQ	Crystal structure of the KOW6-KOW7 domain of human DSIF Descriptor: CHLORIDE ION, SODIUM ION, Transcription elongation factor SPT5 Authors: Bernecky, C, Plitzko, J.M, Cramer, P. Deposit date: 2017-07-17 Release date: 2017-09-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.098 Å) Cite: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
4FHF	Spore photoproduct lyase C140A mutant with dinucleoside spore photoproduct Descriptor: 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-[[(5R)-1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-methyl-2,4-bis(oxidanylidene)-1,3-diazinan-5-yl]methyl]pyrimidine-2,4-dione, IRON/SULFUR CLUSTER, PYROPHOSPHATE 2-, ... Authors: Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. Deposit date: 2012-06-06 Release date: 2012-07-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res., 40, 2012
4DDW	Thermotoga maritima reverse gyrase, c-centered orthorhombic form Descriptor: MAGNESIUM ION, PYROPHOSPHATE 2-, Reverse gyrase, ... Authors: Rudolph, M.G, Klostermeier, D. Deposit date: 2012-01-19 Release date: 2012-12-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling. Nucleic Acids Res., 41, 2013
3QWG	Crystal structure of EspRdelta10, C-terminal 10 amino acids deletion mutant of EspR transcription factor from Mycobacterium tuberculosis Descriptor: ESX-1 secretion-associated regulator EspR Authors: Blasco, B, Pojer, F, Cole, S.T. Deposit date: 2011-02-28 Release date: 2011-09-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.992 Å) Cite: Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis. Mol.Microbiol., 82, 2011
3EBE	Crystal structure of xenopus laevis replication initiation factor MCM10 internal domain Descriptor: Protein MCM10 homolog, ZINC ION Authors: Warren, E.M, Eichman, B.F. Deposit date: 2008-08-27 Release date: 2008-12-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for DNA binding by replication initiator mcm10. Structure, 16, 2008
8BT1	YdaT transcription regulator (CII functional analog) Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ... Authors: Prolic-Kalinsek, M, Loris, R. Deposit date: 2022-11-27 Release date: 2023-02-22 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.39788437 Å) Cite: Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7. Acta Crystallogr D Struct Biol, 79, 2023
4O67	Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP Authors: Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. Deposit date: 2013-12-20 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.444 Å) Cite: The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
4O68	Structure of human cyclic GMP-AMP synthase (cGAS) Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. Deposit date: 2013-12-20 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.436 Å) Cite: The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
4O69	Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion Descriptor: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION Authors: Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. Deposit date: 2013-12-20 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.252 Å) Cite: The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
1J54	Structure of the N-terminal exonuclease domain of the epsilon subunit of E.coli DNA polymerase III at pH 5.8 Descriptor: 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ... Authors: Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E. Deposit date: 2002-01-22 Release date: 2002-10-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome Structure, 10, 2002
1ZBB	Structure of the 4_601_167 Tetranucleosome Descriptor: DNA STRAND 1 (ARBITRARY MODEL SEQUENCE), DNA STRAND 2 (ARBITRARY MODEL SEQUENCE), HISTONE H3, ... Authors: Schalch, T, Duda, S, Sargent, D.F, Richmond, T.J. Deposit date: 2005-04-08 Release date: 2005-07-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (9 Å) Cite: X-ray structure of a tetranucleosome and its implications for the chromatin fibre. Nature, 436, 2005

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