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1RCB
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BU of 1rcb by Molmil
CRYSTAL STRUCTURE OF HUMAN RECOMBINANT INTERLEUKIN-4 AT 2.25 ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-4
Authors:Wlodawer, A, Pavlovsky, A, Gustchina, A.
Deposit date:1992-08-26
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human recombinant interleukin-4 at 2.25 A resolution.
FEBS Lett., 309, 1992
1B0F
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BU of 1b0f by Molmil
CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE WITH MDL 101, 146
Descriptor: 1-{3-METHYL-2-[4-(MORPHOLINE-4-CARBONYL)-BENZOYLAMINO]-BUTYRYL}-PYRROLIDINE-2-CARBOXYLIC ACID (3,3,4,4,4-PENTAFLUORO-1-ISOPROPYL-2-OXO-BUTYL)-AMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (ELASTASE)
Authors:Schreuder, H.A, Metz, W.A, Peet, N.P, Pelton, J.T, Tardif, C.
Deposit date:1998-11-09
Release date:1998-11-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones.
J.Med.Chem., 41, 1998
7E29
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BU of 7e29 by Molmil
Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP
Descriptor: Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Li, J, Smolle, M, Liang, H, Liu, Y.
Deposit date:2021-02-05
Release date:2022-02-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function.
Nucleic Acids Res., 50, 2022
2NXP
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BU of 2nxp by Molmil
Structure of NTD2 domain of the human TAF5 subunit of TFIID
Descriptor: CALCIUM ION, Transcription initiation factor TFIID subunit 5
Authors:Bhattacharya, S, Takada, S, Jacobson, R.H.
Deposit date:2006-11-17
Release date:2007-01-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural analysis and dimerization potential of the human TAF5 subunit of TFIID.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1B38
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BU of 1b38 by Molmil
HUMAN CYCLIN-DEPENDENT KINASE 2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (CELL DIVISION PROTEIN KINASE 2)
Authors:Brown, N.R, Noble, M.E.M, Lawrie, A.M, Morris, M.C, Tunnah, P, Divita, G, Johnson, L.N, Endicott, J.A.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity.
J.Biol.Chem., 274, 1999
4G7P
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BU of 4g7p by Molmil
Rat Heme Oxygenase-1 in complex with Heme and CO with 1 hr Illumination at 100 K: Laser off
Descriptor: CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ...
Authors:Sugishima, M, Moffat, K, Noguchi, M.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
4G92
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BU of 4g92 by Molmil
CCAAT-binding complex from Aspergillus nidulans with DNA
Descriptor: DNA, HAPB protein, HapE, ...
Authors:Huber, E.M, Scharf, D.H, Hortschansky, P, Groll, M, Brakhage, A.A.
Deposit date:2012-07-23
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex.
Structure, 20, 2012
4G8P
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BU of 4g8p by Molmil
Rat Heme Oxygenase-1 in complex with Heme and CO with 16 hr Illumination: Laser on
Descriptor: CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ...
Authors:Sugishima, M, Moffat, K, Noguchi, M.
Deposit date:2012-07-23
Release date:2012-10-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
1A6Q
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BU of 1a6q by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Descriptor: MANGANESE (II) ION, PHOSPHATASE 2C, PHOSPHATE ION
Authors:Das, A.K, Helps, N.R, Cohen, P.T.W, Barford, D.
Deposit date:1998-02-27
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution.
EMBO J., 15, 1996
1AHD
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BU of 1ahd by Molmil
DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX
Descriptor: DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia
Authors:Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K.
Deposit date:1993-04-02
Release date:1993-10-31
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex.
J.Mol.Biol., 234, 1993
4G7U
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BU of 4g7u by Molmil
Rat Heme Oxygenase-1 in complex with Heme and CO with 16 hr Illumination: Laser off
Descriptor: CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ...
Authors:Sugishima, M, Moffat, K, Noguchi, M.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis.
Biochemistry, 51, 2012
1RO4
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BU of 1ro4 by Molmil
RDC-derived models of the zinc ribbon domain of human general transcription factor TFIIB (zinc free structures)
Descriptor: Transcription initiation factor IIB
Authors:Ghosh, M, Ikura, M.
Deposit date:2003-12-01
Release date:2004-05-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB.
Biochem.J., 378, 2004
1BUH
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BU of 1buh by Molmil
CRYSTAL STRUCTURE OF THE HUMAN CDK2 KINASE COMPLEX WITH CELL CYCLE-REGULATORY PROTEIN CKSHS1
Descriptor: PROTEIN (CDK2 HUMAN), PROTEIN (CKSHS1 HUMAN)
Authors:Bourne, Y, Tainer, J.A.
Deposit date:1998-09-03
Release date:1998-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1.
Cell(Cambridge,Mass.), 84, 1996
1BLX
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BU of 1blx by Molmil
P19INK4D/CDK6 COMPLEX
Descriptor: CALCIUM ION, CYCLIN-DEPENDENT KINASE 6, P19INK4D
Authors:Brotherton, D.H, Dhanaraj, V, Wick, S, Brizuela, L, Domaille, P.J, Volyanik, E, Xu, X, Parisini, E, Smith, B.O, Archer, S.J, Serrano, M, Brenner, S.L, Blundell, T.L, Laue, E.D.
Deposit date:1998-07-21
Release date:1999-06-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.
Nature, 395, 1998
4HCA
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BU of 4hca by Molmil
DNA binding by GATA transcription factor-complex 1
Descriptor: DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Chen, Y, Bates, D.L, Dey, R, Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
1RLY
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BU of 1rly by Molmil
RDC-derived models of the zinc ribbon domain of human general transcription TFIIB (zinc bound structures)
Descriptor: Transcription initiation factor IIB, ZINC ION
Authors:Ghosh, M, Ikura, M.
Deposit date:2003-11-26
Release date:2004-05-25
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB.
Biochem.J., 378, 2004
4F8C
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BU of 4f8c by Molmil
Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8
Descriptor: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8
Authors:Crow, A, Banfield, M.
Deposit date:2012-05-17
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif
Proc.Natl.Acad.Sci.USA, 2012
4FR3
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BU of 4fr3 by Molmil
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H
Descriptor: (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, MAGNESIUM ION, ...
Authors:Ottmann, C, Anders, C, Schumacher, B.
Deposit date:2012-06-26
Release date:2013-05-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface.
Chem.Biol., 20, 2013
4F0A
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BU of 4f0a by Molmil
Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-8, PALMITOLEIC ACID, ...
Authors:Janda, C.Y, Waghray, D, Levin, A.M, Thomas, C, Garcia, K.C.
Deposit date:2012-05-03
Release date:2012-06-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural basis of Wnt recognition by Frizzled.
Science, 337, 2012
4FKP
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BU of 4fkp by Molmil
Crystal structure of the cdk2 in complex with oxindole inhibitor
Descriptor: 3-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE, Cyclin-dependent kinase 2, SODIUM ION
Authors:Kang, Y.N, Stuckey, J.A.
Deposit date:2012-06-13
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the cdk2 in complex with oxindole inhibitor
To be Published
4FKO
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BU of 4fko by Molmil
Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor
Descriptor: 2-chloro-N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethylbenzene-1,4-diamine, ACETATE ION, Cyclin-dependent kinase 2
Authors:Kang, Y.N, Stuckey, J.A.
Deposit date:2012-06-13
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the cdk2 in complex with thiazolylpyrimidine inhibitor
To be Published
4FKJ
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BU of 4fkj by Molmil
Crystal structure of the cdk2 in complex with aminopyrazole inhibitor
Descriptor: ACETATE ION, Cyclin-dependent kinase 2, N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]acetamide
Authors:Kang, Y.N, Stuckey, J.A.
Deposit date:2012-06-13
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structure of the cdk2 in complex with aminopyrazole inhibitor
To be Published
4FKW
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BU of 4fkw by Molmil
Crystal structure of the cdk2 in complex with oxindole inhibitor
Descriptor: 2-methylpropyl (3Z)-2-oxo-3-[2-(4-sulfamoylphenyl)hydrazinylidene]-2,3-dihydro-1H-indole-5-carboxylate, Cyclin-dependent kinase 2, GLYCEROL
Authors:Kang, Y.N, Stuckey, J.A.
Deposit date:2012-06-13
Release date:2013-05-08
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the cdk2 in complex with oxindole inhibitor
To be Published
4FL5
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BU of 4fl5 by Molmil
Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS214
Descriptor: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
Authors:Schumacher, B, Ottmann, C.
Deposit date:2012-06-14
Release date:2013-12-11
Last modified:2017-06-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau.
FASEB J., 29, 2015
4GUL
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BU of 4gul by Molmil
Study on structure and function relationships in human ferric Pirin
Descriptor: FE (III) ION, Pirin
Authors:Liu, F, Rehmani, I, Fu, R, Esaka, S, Chen, L, Serrano, V, Liu, A.
Deposit date:2012-08-29
Release date:2013-05-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110, 2013

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