PDB: 8717 resultsInfo pagesStatus searchChemie searchBIRD

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6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Lukarska, M, Cusack, S. Deposit date: 2018-01-14 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
6FHH	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated. Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Lukarska, M, Cusack, S. Deposit date: 2018-01-14 Release date: 2019-01-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
7O7Z	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O81	Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O7Y	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O80	Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. Deposit date: 2021-04-14 Release date: 2021-06-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
283D	A CURVED RNA HELIX INCORPORATING AN INTERNAL LOOP WITH G-A AND A-A NON-WATSON-CRICK BASE PAIRING Descriptor: MANGANESE (II) ION, RNA (5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*GP*GP*CP*C)-3') Authors: Baeyens, K.J, De Bondt, H.L, Pardi, A, Holbrook, S.R. Deposit date: 1996-09-03 Release date: 1996-09-30 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A curved RNA helix incorporating an internal loop with G.A and A.A non-Watson-Crick base pairing. Proc.Natl.Acad.Sci.USA, 93, 1996
7NWG	Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. Descriptor: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... Authors: Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. Deposit date: 2021-03-16 Release date: 2021-07-07 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
6Z6N	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6Z6M	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
7SLQ	Cryo-EM structure of 7SK core RNP with circular RNA Descriptor: 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Minimal circular 7SK RNA, ... Authors: Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. Deposit date: 2021-10-24 Release date: 2022-03-30 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol.Cell, 82, 2022
7SLP	Cryo-EM structure of 7SK core RNP with linear RNA Descriptor: 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Linear 7SK RNA, ... Authors: Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. Deposit date: 2021-10-24 Release date: 2022-03-30 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol.Cell, 82, 2022
7QGG	Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Pulk, A, Kipper, K, Mansour, A. Deposit date: 2021-12-08 Release date: 2022-10-26 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state. J.Mol.Biol., 434, 2022
5FZ5	Transcription initiation complex structures elucidate DNA opening (CC) Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. Deposit date: 2016-03-10 Release date: 2016-05-18 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (8.8 Å) Cite: Transcription Initiation Complex Structures Elucidate DNA Opening Nature, 533, 2016
8P4E	Structural insights into human co-transcriptional capping - structure 5 Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (26-MER), DNA (35-MER), ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-07-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
5FYW	Transcription initiation complex structures elucidate DNA opening (OC) Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. Deposit date: 2016-03-10 Release date: 2016-05-18 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.35 Å) Cite: Transcription Initiation Complex Structures Elucidate DNA Opening Nature, 533, 2016
8P7D	CryoEM structure of METTL6 tRNA SerRS complex in a 1:1:2 stoichiometry Descriptor: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Serine tRNA, ... Authors: Throll, P, Dolce, L.G, Kowalinski, E. Deposit date: 2023-05-30 Release date: 2024-06-12 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 2024
8P7B	CryoEM structure of METTL6 tRNA SerRS complex in a 1:2:2 stoichiometry Descriptor: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Serine tRNA, ... Authors: Throll, P, Dolce, L.G, Kowalinski, E. Deposit date: 2023-05-30 Release date: 2024-06-12 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.42 Å) Cite: Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 2024
8P7C	CryoEM structure of METTL6 tRNA SerRS complex in a 2:2:2 stoichiometry Descriptor: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Serine tRNA, ... Authors: Throll, P, Dolce, L.G, Kowalinski, E. Deposit date: 2023-05-30 Release date: 2024-06-12 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of tRNA recognition by the m 3 C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase. Nat.Struct.Mol.Biol., 2024
6Z6L	Cryo-EM structure of human CCDC124 bound to 80S ribosomes Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
3K5O	Crystal structure of E.coli Pol II Descriptor: DNA polymerase II Authors: Yang, W, Wang, F. Deposit date: 2009-10-07 Release date: 2010-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
3K59	Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... Authors: Yang, W, Wang, F. Deposit date: 2009-10-06 Release date: 2010-02-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3K5N	Crystal structure of E.coli Pol II-abasic DNA binary complex Descriptor: DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II Authors: Yang, W, Wang, F. Deposit date: 2009-10-07 Release date: 2010-02-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
8P4F	Structural insights into human co-transcriptional capping - structure 6 Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (38-MER), ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-07-19 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
7ABG	Human pre-Bact-1 spliceosome Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... Authors: Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. Deposit date: 2020-09-07 Release date: 2020-12-23 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (7.8 Å) Cite: Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020

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