2NDP
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![BU of 2ndp by Molmil](/molmil-images/mine/2ndp) | Structure of DNA-binding HU protein from micoplasma Mycoplasma gallisepticum | Descriptor: | Histone-like DNA-binding superfamily protein | Authors: | Altukhov, D.A, Talyzina, A.A, Agapova, Y.K, Vlaskina, A.V, Korzhenevskiy, D.A, Bocharov, E.V, Rakitina, T.V, Timofeev, V.I, Popov, V.O. | Deposit date: | 2016-09-13 | Release date: | 2016-11-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Enhanced conformational flexibility of the histone-like (HU) protein from Mycoplasma gallisepticum. J.Biomol.Struct.Dyn., 36, 2018
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7TQN
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![BU of 7tqn by Molmil](/molmil-images/mine/7tqn) | |
7TQO
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![BU of 7tqo by Molmil](/molmil-images/mine/7tqo) | |
7TQP
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![BU of 7tqp by Molmil](/molmil-images/mine/7tqp) | Structure of human TREX1 | Descriptor: | SULFATE ION, Three-prime repair exonuclease 1 | Authors: | Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. | Deposit date: | 2022-01-26 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13, 2022
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5WX8
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![BU of 5wx8 by Molmil](/molmil-images/mine/5wx8) | Human herpesvirus 6A immediate early protein 2 C-terminal domain | Descriptor: | Immediate-early protein 2 | Authors: | Nishimura, M, Wang, J, Wakata, A, Sakamoto, K, Mori, Y. | Deposit date: | 2017-01-06 | Release date: | 2017-08-02 | Last modified: | 2017-12-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2. J. Virol., 91, 2017
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6Z6E
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![BU of 6z6e by Molmil](/molmil-images/mine/6z6e) | Crystal structure of the HK97 bacteriophage small terminase | Descriptor: | IODIDE ION, Terminase small subunit | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | Deposit date: | 2020-05-28 | Release date: | 2021-06-09 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system. Nucleic Acids Res., 50, 2022
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3ON0
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![BU of 3on0 by Molmil](/molmil-images/mine/3on0) | Crystal structure of the pED208 TraM-sbmA complex | Descriptor: | Protein traM, sbmA | Authors: | Wong, J.J.W, Lu, J, Edwards, R.A, Frost, L.S, Mark Glover, J.N. | Deposit date: | 2010-08-27 | Release date: | 2011-05-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.874 Å) | Cite: | Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM. Nucleic Acids Res., 39, 2011
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2LF7
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![BU of 2lf7 by Molmil](/molmil-images/mine/2lf7) | |
2ME0
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![BU of 2me0 by Molmil](/molmil-images/mine/2me0) | |
3IL2
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![BU of 3il2 by Molmil](/molmil-images/mine/3il2) | |
5FW1
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![BU of 5fw1 by Molmil](/molmil-images/mine/5fw1) | Crystal structure of SpyCas9 variant VQR bound to sgRNA and TGAG PAM target DNA | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | Authors: | Anders, C, Bargsten, K, Jinek, M. | Deposit date: | 2016-02-11 | Release date: | 2016-04-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
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7B4G
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![BU of 7b4g by Molmil](/molmil-images/mine/7b4g) | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (II) | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, ... | Authors: | Degtjarik, O, Rozenberg, H, Shakked, Z. | Deposit date: | 2020-12-02 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Nat Commun, 12, 2021
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7UJN
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![BU of 7ujn by Molmil](/molmil-images/mine/7ujn) | Structure of Human SAMHD1 with Non-Hydrolysable dGTP Analog | Descriptor: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | Authors: | Huynh, K.W, Ammirati, M, Han, S. | Deposit date: | 2022-03-31 | Release date: | 2022-07-20 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation and ssDNA binding kinetics. Nucleic Acids Res., 50, 2022
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5FW3
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![BU of 5fw3 by Molmil](/molmil-images/mine/5fw3) | Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | Authors: | Anders, C, Bargsten, K, Jinek, M. | Deposit date: | 2016-02-11 | Release date: | 2016-06-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
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5FW2
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![BU of 5fw2 by Molmil](/molmil-images/mine/5fw2) | Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | Authors: | Anders, C, Bargsten, K, Jinek, M. | Deposit date: | 2016-02-11 | Release date: | 2016-06-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.676 Å) | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
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3IKT
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![BU of 3ikt by Molmil](/molmil-images/mine/3ikt) | |
4ZN1
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![BU of 4zn1 by Molmil](/molmil-images/mine/4zn1) | Crystal Structure of MjSpt4:Spt5 complex conformation A | Descriptor: | Transcription elongation factor Spt4, Transcription elongation factor Spt5, ZINC ION | Authors: | Guo, G.R, Zhou, H.H, Gao, Y.X, Zhu, Z.L, Niu, L.W, Teng, M.K. | Deposit date: | 2015-05-04 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biochemical insights into the DNA-binding mode of MjSpt4p:Spt5 complex at the exit tunnel of RNAPII J.Struct.Biol., 192, 2015
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2I9T
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![BU of 2i9t by Molmil](/molmil-images/mine/2i9t) | Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter | Descriptor: | 5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*CP*TP*G)-3', 5'-D(*CP*AP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*CP*T)-3', Nuclear factor NF-kappa-B p105 subunit, ... | Authors: | Escalante, C.R, Shen, L, Thanos, D, Aggarwal, A.K. | Deposit date: | 2006-09-06 | Release date: | 2007-02-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter Structure, 10, 2002
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3HIF
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![BU of 3hif by Molmil](/molmil-images/mine/3hif) | The crystal structure of apo wild type CAP at 3.6 A resolution. | Descriptor: | Catabolite gene activator | Authors: | Steitz, T.A, Sharma, H, Wang, J, Kong, J, Yu, S. | Deposit date: | 2009-05-19 | Release date: | 2009-09-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding. Proc.Natl.Acad.Sci.USA, 106, 2009
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7O7B
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8PVT
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![BU of 8pvt by Molmil](/molmil-images/mine/8pvt) | |
8PVZ
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![BU of 8pvz by Molmil](/molmil-images/mine/8pvz) | |
6Z6D
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![BU of 6z6d by Molmil](/molmil-images/mine/6z6d) | Crystal structure of the HK97 bacteriophage large terminase | Descriptor: | BROMIDE ION, Terminase large subunit | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | Deposit date: | 2020-05-28 | Release date: | 2021-06-09 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system. Nucleic Acids Res., 50, 2022
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2D1H
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![BU of 2d1h by Molmil](/molmil-images/mine/2d1h) | Crystal structure of ST1889 protein from thermoacidophilic archaeon Sulfolobus tokodaii | Descriptor: | 109aa long hypothetical transcriptional regulator | Authors: | Shinkai, A, Sekine, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-08-22 | Release date: | 2006-09-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The putative DNA-binding protein Sto12a from the thermoacidophilic archaeon Sulfolobus tokodaii contains intrachain and interchain disulfide bonds. J.Mol.Biol., 372, 2007
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7UFI
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![BU of 7ufi by Molmil](/molmil-images/mine/7ufi) | VchTnsC AAA+ ATPase with DNA, single heptamer | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ... | Authors: | Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2022-03-22 | Release date: | 2022-06-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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