4B8P
| rImp_alpha_A89NLS | Descriptor: | A89NLS, IMPORTIN SUBUNIT ALPHA-1A | Authors: | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | Deposit date: | 2012-08-29 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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4BA3
| mImp_alphadIBB_A89NLS | Descriptor: | A89NLS, IMPORTIN SUBUNIT ALPHA-2 | Authors: | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | Deposit date: | 2012-09-11 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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4B8J
| rImp_alpha1a | Descriptor: | IMPORTIN SUBUNIT ALPHA-1A | Authors: | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | Deposit date: | 2012-08-28 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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3IK5
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3IOZ
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7T12
| Hexameric HIV-1 (O-group) CA | Descriptor: | Capsid protein p24 | Authors: | Jacques, D.A, James, L.C. | Deposit date: | 2021-12-01 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Evasion of cGAS and TRIM5 defines pandemic HIV. Nat Microbiol, 7, 2022
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4A0L
| Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex | Descriptor: | 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ... | Authors: | Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. | Deposit date: | 2011-09-09 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (7.4 Å) | Cite: | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
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4A0K
| STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX | Descriptor: | 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ... | Authors: | Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. | Deposit date: | 2011-09-09 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (5.93 Å) | Cite: | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
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8VBK
| Structure of bovine anti-HIV Fab ElsE5 | Descriptor: | Bovine Fab ElsE5 heavy chain, Bovine Fab ElsE5 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBO
| Structure of bovine anti-HIV Fab ElsE9 | Descriptor: | Bovine Fab ElsE9 heavy chain, Bovine Fab ElsE9 light chain, GLYCEROL, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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5MJU
| Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101 | Descriptor: | (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1 | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | Deposit date: | 2016-12-01 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.71 Å) | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544, 2017
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8QRQ
| ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.2) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRW
| ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up) | Descriptor: | Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRR
| ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.3) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRP
| ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.1) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRU
| ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-down) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0) | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRS
| ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-up) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0) | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRO
| ASCT2 trimer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QRV
| ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the outward-facing state (OFS) | Descriptor: | Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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5LLU
| Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP | Descriptor: | ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, SODIUM ION | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | Deposit date: | 2016-07-28 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544, 2017
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5LM4
| Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101 | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | Deposit date: | 2016-07-29 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544, 2017
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5LLM
| Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP and the allosteric inhibitor UCPH101 | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... | Authors: | Canul-Tec, J, Assal, R, Legrand, P, Reyes, N. | Deposit date: | 2016-07-27 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature, 544, 2017
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7AWP
| Structure of the thermostabilized EAAT1 cryst-II mutant in complex with rubidium and barium ions and the allosteric inhibitor UCPH101 | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... | Authors: | Canul-Tec, J.C, Legrand, P, Reyes, N. | Deposit date: | 2020-11-08 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.91 Å) | Cite: | The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
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7AWM
| Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP, three sodium ions and the allosteric inhibitor UCPH101 | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ... | Authors: | Canul-Tec, J.C, Legrand, P, Reyes, N. | Deposit date: | 2020-11-08 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
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7AWQ
| Structure of the thermostabilized EAAT1 cryst-E386Q mutant in complex with L-ASP, sodium ions and the allosteric inhibitor UCPH101 | Descriptor: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ... | Authors: | Canul-Tec, J.C, Legrand, P, Reyes, N. | Deposit date: | 2020-11-08 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
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