5Y15
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![BU of 5y15 by Molmil](/molmil-images/mine/5y15) | Crystal structure of human DUSP28 | Descriptor: | Dual specificity phosphatase 28, PHOSPHATE ION | Authors: | Ku, B, Hong, W, Kim, S.J, Ryu, S.E. | Deposit date: | 2017-07-19 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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5Y16
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![BU of 5y16 by Molmil](/molmil-images/mine/5y16) | Crystal structure of human DUSP28(Y102H) | Descriptor: | CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION | Authors: | Ku, B, Kim, M, Kim, S.J, Ryu, S.E. | Deposit date: | 2017-07-19 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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5Z59
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![BU of 5z59 by Molmil](/molmil-images/mine/5z59) | Crystal structure of Tk-PTP in the inactive form | Descriptor: | Protein-tyrosine phosphatase | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | Deposit date: | 2018-01-17 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5Z5A
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![BU of 5z5a by Molmil](/molmil-images/mine/5z5a) | Crystal structure of Tk-PTP in the active form | Descriptor: | Protein-tyrosine phosphatase, VANADATE ION | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | Deposit date: | 2018-01-17 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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5Z5B
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![BU of 5z5b by Molmil](/molmil-images/mine/5z5b) | Crystal structure of Tk-PTP in the G95A mutant form | Descriptor: | CHLORIDE ION, FORMIC ACID, Protein-tyrosine phosphatase | Authors: | Ku, B, Yun, H.Y, Kim, S.J. | Deposit date: | 2018-01-17 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
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6APX
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![BU of 6apx by Molmil](/molmil-images/mine/6apx) | Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1 | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Monobody YSX1, ... | Authors: | Gumpena, R, Lountos, G.T, Sreejith, R.K, Tropea, J.E, Cherry, S, Waugh, D.S. | Deposit date: | 2017-08-18 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.491 Å) | Cite: | Crystal structure of the human dual specificity phosphatase 1 catalytic domain. Protein Sci., 27, 2018
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6D65
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![BU of 6d65 by Molmil](/molmil-images/mine/6d65) | Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein off7 | Descriptor: | Designed AR protein off7, ETHANOL, GLYCEROL, ... | Authors: | Gumpena, R, Lountos, G.T, Waugh, D.S. | Deposit date: | 2018-04-20 | Release date: | 2018-09-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.348 Å) | Cite: | MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
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6D66
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![BU of 6d66 by Molmil](/molmil-images/mine/6d66) | Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16 | Descriptor: | 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Gumpena, R, Waugh, D.S, Lountos, G.T. | Deposit date: | 2018-04-20 | Release date: | 2018-09-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.226 Å) | Cite: | MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
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6D67
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![BU of 6d67 by Molmil](/molmil-images/mine/6d67) | Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Designed AR protein mbp3_16, ... | Authors: | Gumpena, R, Lountos, G.T, Waugh, D.S. | Deposit date: | 2018-04-20 | Release date: | 2018-09-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
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6G84
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![BU of 6g84 by Molmil](/molmil-images/mine/6g84) | Structure of Cdc14 bound to CBK1 PxL motif | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CBK1, ... | Authors: | Mouilleron, S, Kataria, M, Uhlmann, F. | Deposit date: | 2018-04-07 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018
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6G85
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![BU of 6g85 by Molmil](/molmil-images/mine/6g85) | Structure of Cdc14 bound to CBK1 PxL motif | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CBK1, ... | Authors: | Mouilleron, S, Kataria, M, Uhlmann, F. | Deposit date: | 2018-04-07 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.528 Å) | Cite: | A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018
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6G86
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![BU of 6g86 by Molmil](/molmil-images/mine/6g86) | Structure of Cdc14 bound to SIC1 PxL motif | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, ... | Authors: | Mouilleron, S, Kataria, M, Uhlmann, F. | Deposit date: | 2018-04-07 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018
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6I28
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![BU of 6i28 by Molmil](/molmil-images/mine/6i28) | Crystal Structure of Cydia Pomonella PTP-2 phosphatase | Descriptor: | CALCIUM ION, GLYCEROL, ORF98 PTP-2 | Authors: | Huang, G, Keown, J.P, Oliver, M.R, Metcalf, P. | Deposit date: | 2018-10-31 | Release date: | 2019-02-20 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus. Acta Crystallogr.,Sect.F, 75, 2019
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6L1S
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![BU of 6l1s by Molmil](/molmil-images/mine/6l1s) | Crystal structure of DUSP22 mutant_C88S | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Chang, C.C, Lyu, P.C. | Deposit date: | 2019-09-30 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3611 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LMY
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![BU of 6lmy by Molmil](/molmil-images/mine/6lmy) | Crystal structure of DUSP22 mutant_C88S/S93A | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2019-12-27 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LOT
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![BU of 6lot by Molmil](/molmil-images/mine/6lot) | Crystal structure of DUSP22 mutant_N128D | Descriptor: | Dual specificity protein phosphatase 22, SULFATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2020-01-07 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LOU
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![BU of 6lou by Molmil](/molmil-images/mine/6lou) | Crystal structure of DUSP22 mutant_C88S/S93N | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2020-01-07 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5301 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6LVQ
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![BU of 6lvq by Molmil](/molmil-images/mine/6lvq) | Crystal structure of DUSP22_VO4 | Descriptor: | Dual specificity protein phosphatase 22, VANADATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2020-02-04 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6MC1
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![BU of 6mc1 by Molmil](/molmil-images/mine/6mc1) | Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-(methylthio)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3,3-dimethyl-1-{[9-(methylsulfanyl)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one, ACETATE ION, ... | Authors: | Gannam, Z.T.K, Anderson, K.S, Bennett, A.M, Lolis, E. | Deposit date: | 2018-08-30 | Release date: | 2020-08-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An allosteric site on MKP5 reveals a strategy for small-molecule inhibition. Sci.Signal., 13, 2020
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6N8M
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![BU of 6n8m by Molmil](/molmil-images/mine/6n8m) | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | Descriptor: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8N
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![BU of 6n8n by Molmil](/molmil-images/mine/6n8n) | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8O
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![BU of 6n8o by Molmil](/molmil-images/mine/6n8o) | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6RZZ
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![BU of 6rzz by Molmil](/molmil-images/mine/6rzz) | |
6S05
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![BU of 6s05 by Molmil](/molmil-images/mine/6s05) | |
6WUS
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![BU of 6wus by Molmil](/molmil-images/mine/6wus) | |