PDB: 533 resultsInfo pagesStatus searchChemie searchBIRD

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4OMQ	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant S94A Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2015-01-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
4OMM	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant N113S Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2015-01-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
4OMP	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-01-27 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
3EG2	Crystal structure of the N114Q mutant of ABL-SH3 domain Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
3EG1	Crystal structure of the N114Q mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions Descriptor: Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION, p41 peptide Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
3EGU	Crystal structure of the N114A mutant of ABL-SH3 domain Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION Authors: Camara-Artigas, A. Deposit date: 2008-09-11 Release date: 2009-09-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
3EG3	Crystal structure of the N114A mutant of ABL-SH3 domain Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
3EG0	Crystal structure of the N114T mutant of ABL-SH3 domain Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
4ESR	Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors Descriptor: DI(HYDROXYETHYL)ETHER, Jouberin Authors: Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X. Deposit date: 2012-04-23 Release date: 2012-06-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors. Proteomics, 12, 2012
4F16	Crystal Structure of the alpha spectrin SH3 domain at pH 5 Descriptor: Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain at pH 5 To be Published
4F17	Crystal Structure of the alpha spectrin SH3 domain at pH 9 Descriptor: Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain at pH 9 To be Published
4FSS	Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-06-27 Release date: 2012-07-18 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution To be published
5QU8	Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV Descriptor: Cytoplasmic protein NCK1, SODIUM ION Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (0.93 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU3	Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.02 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QUA	Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221 Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU1	Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A Descriptor: Cytoplasmic protein NCK1, SULFATE ION Authors: Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.08 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU5	Domain Swap in the first SH3 domain of human Nck1 Descriptor: Cytoplasmic protein NCK1 Authors: Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.11 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU2	Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY Descriptor: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.04 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU7	Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU4	Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU6	Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.816 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
3M0P	Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 4. Descriptor: SULFATE ION, Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2010-03-03 Release date: 2011-01-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures Acta Crystallogr.,Sect.D, 2011
3M0S	Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 7 Descriptor: SULFATE ION, Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2010-03-03 Release date: 2011-01-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures Acta Crystallogr.,Sect.D, 2011
3M0R	Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 6. Descriptor: SULFATE ION, Spectrin alpha chain, brain Authors: Gavira, J.A, Camara-Artigas, A. Deposit date: 2010-03-03 Release date: 2011-01-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures Acta Crystallogr.,Sect.D, 2011
3M0T	Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 9. Descriptor: SULFATE ION, Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2010-03-03 Release date: 2011-01-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures Acta Crystallogr.,Sect.D, 2011

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