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5JKS
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BU of 5jks by Molmil
vaccinia virus D4 R167A mutant /A20(1-50)
Descriptor: DNA polymerase processivity factor component A20, SULFATE ION, Uracil-DNA glycosylase
Authors:Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Peyrefitte, C.N, Iseni, F.
Deposit date:2016-04-26
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Acta Crystallogr.,Sect.F, 72, 2016
6MQK
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BU of 6mqk by Molmil
Crystal Structure of GTPase Domain of Human Septin 12 in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-12
Authors:Castro, D.K.S.V, Pereira, H.M, Brandao-Neto, J, Ulian, A.P.U, Garratt, R.C.
Deposit date:2018-10-10
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface.
Iucrj, 7, 2020
5JKR
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BU of 5jkr by Molmil
vaccinia virus D4/A20(1-50)w43a mutant
Descriptor: DNA polymerase processivity factor component A20, SULFATE ION, Uracil-DNA glycosylase
Authors:Contesto-Richefeu, C, Tarbouriech, N, Brazzolotto, X, Burmeister, W.P, Peyrefitte, C.N, Iseni, F.
Deposit date:2016-04-26
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Acta Crystallogr.,Sect.F, 72, 2016
6MQB
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BU of 6mqb by Molmil
Crystal Structure of GTPase Domain of Human Septin 12 in complex with GMPPNP in Space Group C2221
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Septin-12
Authors:Castro, D.K.S.V, Pereira, H.M, Brandao-Neto, J, Ulian, A.P.U, Garratt, R.C.
Deposit date:2018-10-09
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface.
Iucrj, 7, 2020
4OEB
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BU of 4oeb by Molmil
Structure of membrane binding protein pleurotolysin A from Pleurotus ostreatus
Descriptor: Pleurotolysin A, SULFATE ION
Authors:Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P.
Deposit date:2014-01-12
Release date:2015-02-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
7UAK
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BU of 7uak by Molmil
Structure of recombinantly assembled A53E alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Zhou, K, Zhou, H.
Deposit date:2022-03-13
Release date:2023-03-29
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface.
J.Biol.Chem., 299, 2023
6OBZ
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BU of 6obz by Molmil
Crystal structure of FluA-20 Fab
Descriptor: Heavy chain of FluA-20 Fab, Light chain of FluA-20 Fab, Immunoglobulin light chain
Authors:Wilson, I.A, Lang, S.
Deposit date:2019-03-21
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019
4WWI
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BU of 4wwi by Molmil
Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution
Descriptor: Ig gamma-3 chain C region, Immunoglobulin G-binding protein A
Authors:Deis, L.N, Oas, T.G.
Deposit date:2014-11-11
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:Suppression of conformational heterogeneity at a protein-protein interface.
Proc.Natl.Acad.Sci.USA, 112, 2015
6OCB
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BU of 6ocb by Molmil
Crystal structure of FluA-20 Fab in complex with the head domain of H3 (A/Hong Kong/1/1968)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of FluA-20 Fab, Hemagglutinin, ...
Authors:Wilson, I.A, Lang, S.
Deposit date:2019-03-22
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019
6OC3
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BU of 6oc3 by Molmil
Crystal structure of FluA-20 Fab in complex with the head domain of H1 (A/Solomon Islands/3/2006)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of FluA-20 Fab, Hemagglutinin, ...
Authors:Wilson, I.A, Lang, S.
Deposit date:2019-03-21
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019
5LVE
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BU of 5lve by Molmil
STRUCTURE OF THE VARIABLE DOMAIN OF HUMAN IMMUNOGLOBULIN K-4 LIGHT CHAIN LEN
Descriptor: BENCE-JONES PROTEIN LEN, ZINC ION
Authors:Schiffer, M, Huang, D.-B, Chang, C.-H.
Deposit date:1999-02-24
Release date:2000-02-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Protein Sci., 9, 2000
6WC2
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BU of 6wc2 by Molmil
Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex
Descriptor: Homeobox protein Nkx-2.5, MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A, Myocardin Enhancer DNA
Authors:Lei, X, Chen, L.
Deposit date:2020-03-29
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
4OV8
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BU of 4ov8 by Molmil
Crystal Structure of the TMH1-lock mutant of the mature form of pleurotolysin B
Descriptor: CHLORIDE ION, GLYCEROL, Pleurotolysin B, ...
Authors:Kondos, S.C, Law, R.H.P, Whisstock, J.C, Dunstone, M.A.
Deposit date:2014-02-20
Release date:2015-02-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
Plos Biol., 13, 2015
7A8W
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BU of 7a8w by Molmil
Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikC with an engineered HMA domain of Pikp-1 from rice (Oryza sativa)
Descriptor: NBS-LRR class disease resistance protein, Uncharacterized protein
Authors:Maidment, J.H.R, De la Concepcion, J.C, Franceschetti, M, Banfield, M.J.
Deposit date:2020-08-31
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The allelic rice immune receptor Pikh confers extended resistance to strains of the blast fungus through a single polymorphism in the effector binding interface.
Plos Pathog., 17, 2021
6RWH
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BU of 6rwh by Molmil
Fragment AZ-007 binding at a primary and secondary binding site of the the p53pT387/14-3-3 sigma complex
Descriptor: 14-3-3 protein sigma, 5-(1~{H}-imidazol-5-yl)-4-phenyl-thiophene-2-carboximidamide, CALCIUM ION, ...
Authors:Leysen, S, Guillory, X, Wolter, M, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C.
Deposit date:2019-06-05
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Fragment-based Differential Targeting of PPI Stabilizer Interfaces.
J.Med.Chem., 63, 2020
6S9Q
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BU of 6s9q by Molmil
Fragment AZ-004 binding at a primary and secondary site in a p53pT387/14-3-3 complex
Descriptor: 14-3-3 protein sigma, 4-methyl-5-phenyl-thiophene-2-carboximidamide, CALCIUM ION, ...
Authors:Leysen, S, Guillory, X, Wolter, M, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C.
Deposit date:2019-07-15
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Fragment-based Differential Targeting of PPI Stabilizer Interfaces.
J.Med.Chem., 63, 2020
7L6Q
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BU of 7l6q by Molmil
Unliganded ELIC in styrene-maleic-acid nanodiscs at 2.5-Angstrom resolution
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CARDIOLIPIN, Gamma-aminobutyric-acid receptor subunit beta-1
Authors:Grosman, C, Kumar, P.
Deposit date:2020-12-23
Release date:2021-06-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
7L6U
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BU of 7l6u by Molmil
Unliganded ELIC in POPC-only nanodiscs at 3.3-Angstrom resolution
Descriptor: Gamma-aminobutyric-acid receptor subunit beta-1
Authors:Kumar, P, Grosman, C.
Deposit date:2020-12-23
Release date:2021-06-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
8PFH
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BU of 8pfh by Molmil
Crystal structure of the yeast septin complex Shs1-Cdc12-Cdc3-Cdc10
Descriptor: CDC10 isoform 1, CDC12 isoform 1, Cell division control protein 3, ...
Authors:Grupp, B, Denkhaus, L, Gerhardt, S, Gronemeyer, T.
Deposit date:2023-06-16
Release date:2023-12-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity.
Commun Biol, 7, 2024
6NB9
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BU of 6nb9 by Molmil
Amyloid-Beta (20-34) with L-isoaspartate 23
Descriptor: Amyloid-beta A4 protein
Authors:Sawaya, M.R, Warmack, R.A, Boyer, D.R, Zee, C.T, Richards, L.S, Cascio, D, Gonen, T, Clarke, S.G, Eisenberg, D.S.
Deposit date:2018-12-06
Release date:2019-08-07
Last modified:2022-09-07
Method:ELECTRON CRYSTALLOGRAPHY (1.05 Å)
Cite:Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.
Nat Commun, 10, 2019
6W16
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BU of 6w16 by Molmil
Crystal structure of a human metapneumovirus monomeric fusion protein complexed with 458 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 458 Fab heavy chain, 458 Fab light chain, ...
Authors:Huang, J, Mousa, J.J.
Deposit date:2020-03-03
Release date:2020-06-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Antibody recognition of the Pneumovirus fusion protein trimer interface.
Plos Pathog., 16, 2020
4MTU
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BU of 4mtu by Molmil
beta-Alanyl-CoA:Ammonia Lyase from Clostridium propionicum
Descriptor: Beta-alanyl-CoA:ammonia lyase 2, SULFATE ION, ZINC ION
Authors:Heine, A, Reuter, K.
Deposit date:2013-09-20
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:High resolution crystal structure of Clostridium propionicum beta-alanyl-CoA:ammonia lyase, a new member of the "hot dog fold" protein superfamily.
Proteins, 82, 2014
6WC5
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BU of 6wc5 by Molmil
Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex
Descriptor: Homeobox protein Nkx-2.5, Myocardin enhancer DNA, Myocyte-specific enhancer factor 2B
Authors:Chen, L, Lei, X.
Deposit date:2020-03-29
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
4MZQ
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BU of 4mzq by Molmil
beta-Alanyl-CoA:Ammonia Lyase from Clostridium propionicum in complex with propionyl-CoA
Descriptor: beta-Alanyl-CoA:Ammonia Lyase, propionyl Coenzyme A
Authors:Heine, A, Reuter, K.
Deposit date:2013-09-30
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.587 Å)
Cite:High resolution crystal structure of Clostridium propionicum beta-alanyl-CoA:ammonia lyase, a new member of the "hot dog fold" protein superfamily.
Proteins, 82, 2014
4FS0
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BU of 4fs0 by Molmil
Crystal structure of mutant F136D of mouse nectin-2 extracellular fragment D1-D2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor-related protein 2, SULFATE ION
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2012-06-26
Release date:2012-08-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Nectin ectodomain structures reveal a canonical adhesive interface.
Nat.Struct.Mol.Biol., 19, 2012

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