3KS2
 
 | |
4WP4
 | | Hev b 6.02 (hevein) extracted from surgical gloves | | Descriptor: | Pro-hevein, THIOUREA | | Authors: | Galicia, C, Rodriguez-Romero, A. | | Deposit date: | 2014-10-17 | | Release date: | 2015-03-04 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Impact of the vulcanization process on the structural characteristics and IgE recognition of two allergens, Hev b 2 and Hev b 6.02, extracted from latex surgical gloves.
Mol.Immunol., 65, 2015
|
|
6T7Y
 | | Structure of PCNA bound to cPIP motif of DP2 from P. abyssi | | Descriptor: | DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD | | Authors: | Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L. | | Deposit date: | 2019-10-23 | | Release date: | 2020-03-04 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
|
|
6THM
 | | Linalool Dehydratase Isomerase M125A mutant | | Descriptor: | 1,2-ETHANEDIOL, Linalool dehydratase-isomerase protein LDI, MALONATE ION | | Authors: | Cuetos, A, Zukic, E, Danesh-Azari, H.R, Grogan, G. | | Deposit date: | 2019-11-20 | | Release date: | 2020-10-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Using Noncovalent Mechanisms
Acs Catalysis, 2020
|
|
4WOV
 | | CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH BMS-066 AKA 2-METHOXY-N-({6-[3-METHYL-7-(METHYLAMINO)-3,5,8,10-TETRAAZATRICYCLO[7.3.0.0, 6]DODECA-1(9),2(6),4,7,11-PENTAEN-11-YL]PYRIDIN-2-YL}METHY L)ACETAMIDE | | Descriptor: | 2-methoxy-N-({6-[1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]pyridin-2-yl}methyl)acetamide, Non-receptor tyrosine-protein kinase TYK2, SULFATE ION | | Authors: | Muckelbauer, J.K. | | Deposit date: | 2014-10-16 | | Release date: | 2015-03-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.
J.Biol.Chem., 290, 2015
|
|
6T9H
 | |
7OPQ
 | | Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CA1 in C188 | | Descriptor: | 1-[(2~{S})-2-(4-methoxyphenyl)pyrrolidin-1-yl]propan-1-one, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | | Deposit date: | 2021-06-01 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Rsc Med Chem, 13, 2022
|
|
7OPR
 | | Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CB1 in C123 | | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | | Deposit date: | 2021-06-01 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Rsc Med Chem, 13, 2022
|
|
7OPP
 | | Crystal structure of the Rab27a fusion with Slp2a-RBDa1 effector for SF4 pocket drug targeting | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Synaptotagmin-like protein 2,Ras-related protein Rab-27A | | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | | Deposit date: | 2021-06-01 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A.
Rsc Med Chem, 13, 2022
|
|
6TFN
 | |
6T7X
 | | Crystal structure of PCNA from P. abyssi | | Descriptor: | DNA polymerase sliding clamp | | Authors: | Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L. | | Deposit date: | 2019-10-23 | | Release date: | 2020-03-04 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
|
|
6TFR
 | | Linalool Dehydratase Isomerase C180A mutant | | Descriptor: | 1,2-ETHANEDIOL, Linalool dehydratase-isomerase protein LDI | | Authors: | Cuetos, A, Zukic, E, Danesh-Azari, H.R, Grogan, G. | | Deposit date: | 2019-11-14 | | Release date: | 2020-10-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Using Noncovalent Mechanisms
Acs Catalysis, 2020
|
|
6TFT
 | |
4Y7L
 | | T6SS protein TssM C-terminal domain (869-1107) from EAEC | | Descriptor: | GLYCEROL, Type VI secretion protein IcmF, ZINC ION | | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | | Deposit date: | 2015-02-15 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Biogenesis and structure of a type VI secretion membrane core complex.
Nature, 523, 2015
|
|
7ZMD
 | |
7ZMC
 | |
7ZMA
 | |
7ZM9
 | | Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase | | Authors: | Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. | | Deposit date: | 2022-04-19 | | Release date: | 2022-09-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
|
|
7ZMF
 | | Dehydratase domain of module 3 from Brevibacillus Brevis orphan BGC11 | | Descriptor: | GLYCEROL, MAGNESIUM ION, Putative polyketide synthase | | Authors: | Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. | | Deposit date: | 2022-04-19 | | Release date: | 2022-09-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
|
|
8BEW
 | |
4Z98
 | | Crystal Structure of Hen Egg White Lysozyme using Serial X-ray Diffraction Data Collection | | Descriptor: | ACETATE ION, Lysozyme C | | Authors: | Murray, T.D, Lyubimov, A.Y, Ogata, C.M, Uervirojnangkoorn, M, Brunger, A.T, Berger, J.M. | | Deposit date: | 2015-04-10 | | Release date: | 2015-10-14 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | A high-transparency, micro-patternable chip for X-ray diffraction analysis of microcrystals under native growth conditions.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
|
|
5CAO
 | | EGFR kinase domain mutant "TMLR" with compound 29 | | Descriptor: | Epidermal growth factor receptor, N~2~-[2-methyl-2-(methylsulfonyl)propyl]-N~4~-[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]pyrimidine-2,4-diamine | | Authors: | Eigenbrot, C, Yu, C. | | Deposit date: | 2015-06-29 | | Release date: | 2015-10-28 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study.
J.Med.Chem., 58, 2015
|
|
1PBX
 | |
1BJQ
 | | THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH ADENINE | | Descriptor: | ADENINE, CALCIUM ION, LECTIN, ... | | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M. | | Deposit date: | 1998-06-26 | | Release date: | 1998-12-30 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
|
|
5KVM
 | | Extracellular region of mouse GPR56/ADGRG1 in complex with FN3 monobody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G-protein coupled receptor G1, ... | | Authors: | Salzman, G.S, Ding, C, Koide, S, Arac, D. | | Deposit date: | 2016-07-14 | | Release date: | 2016-09-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.449 Å) | | Cite: | Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.
Neuron, 91, 2016
|
|
