PDB: 72960 resultsInfo pagesStatus searchChemie searchBIRD

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3KO3	D-tyrosyl-tRNA(Tyr) deacylase from Plasmodium falciparum incomplex with ADP, obtained through soaking native enzyme crystal with the ATP Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-tyrosyl-tRNA(Tyr) deacylase Authors: Manickam, Y, Bhatt, T.K, Sharma, A. Deposit date: 2009-11-13 Release date: 2009-12-08 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
1CKN	STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, MRNA CAPPING ENZYME, ... Authors: Hakansson, K, Doherty, A.J, Wigley, D.B. Deposit date: 1997-04-20 Release date: 1997-07-07 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes. Cell(Cambridge,Mass.), 89, 1997
1CKM	STRUCTURE OF TWO DIFFERENT CONFORMATIONS OF MRNA CAPPING ENZYME IN COMPLEX WITH GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME Authors: Hakansson, K, Doherty, A.J, Wigley, D.B. Deposit date: 1997-04-20 Release date: 1997-07-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes. Cell(Cambridge,Mass.), 89, 1997
3KNF	Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum Descriptor: D-tyrosyl-tRNA(Tyr) deacylase Authors: Manickam, Y, Bhatt, T.K, Sharma, A. Deposit date: 2009-11-12 Release date: 2009-12-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3 Å) Cite: Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3KO5	D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-tyrosyl-tRNA(Tyr) deacylase Authors: Manickam, Y, Bhatt, T.K, Sharma, A. Deposit date: 2009-11-13 Release date: 2009-12-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
5TQU	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Descriptor: 2-[2-[[3-(1~{H}-benzimidazol-2-ylamino)propylamino]methyl]-4,6-bis(chloranyl)indol-1-yl]ethanol, GLYCEROL, METHIONINE, ... Authors: Barros-Alvarez, X, Hol, W.G.J. Deposit date: 2016-10-24 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis. ACS Infect Dis, 3, 2017
5UNE	Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1 Descriptor: MAGNESIUM ION, RNA (47-MER) Authors: Lares, M, Scott, W.G. Deposit date: 2017-01-30 Release date: 2017-03-29 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.900099 Å) Cite: Dimerized Structure Gives Further Insight Into the Function of the Novel RNA Gene: HAR1 To Be Published
3BLL	TGT mutant in complex with Boc-preQ1 Descriptor: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION, ... Authors: Tidten, N, Heine, A, Reuter, K, Klebe, G. Deposit date: 2007-12-11 Release date: 2008-12-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.26 Å) Cite: Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Plos One, 8, 2013
3BLO	TGT mutant in complex with queuine Descriptor: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... Authors: Tidten, N, Heine, A, Reuter, K, Klebe, G. Deposit date: 2007-12-11 Release date: 2008-12-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Plos One, 8, 2013
4JAH	Crystal structure of 2-Selenouridine containing RNA Descriptor: POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*AP*(RUS)P*AP*C)-3') Authors: Jiang, S, Gan, J, Sun, H, Huang, Z. Deposit date: 2013-02-18 Release date: 2014-01-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of 2-Selenouridine containing RNA To be Published
2LQK	NMR solution structure of the N-terminal domain of the CdnL protein from Thermus thermophilus Descriptor: Transcriptional regulator Authors: Jimenez, M, Padmanabhan, S. Deposit date: 2012-03-09 Release date: 2012-08-01 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: NMR structure note: N-terminal domain of Thermus thermophilus CdnL. J.Biomol.Nmr, 53, 2012
2ZT5	Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with ATP) Descriptor: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Glycyl-tRNA synthetase Authors: Guo, R.T, Yang, X.L, Schimmel, P. Deposit date: 2008-09-19 Release date: 2009-08-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis To be Published
2ZT7	Crystal structure of human Glycyl-tRNA synthetase (GlyRS) in complex with Glycine and ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCINE, Glycyl-tRNA synthetase Authors: Guo, R.T, Yang, X.L, Schimmel, P. Deposit date: 2008-09-19 Release date: 2009-08-25 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis To be Published
3FRH	Structure of the 16S rRNA methylase RmtB, P21 Descriptor: 16S rRNA methylase, S-ADENOSYL-L-HOMOCYSTEINE Authors: Schmitt, E, Galimand, M, Panvert, M, Dupechez, M, Courvalin, P, Mechulam, Y. Deposit date: 2009-01-08 Release date: 2009-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases J.Mol.Biol., 388, 2009
3FRI	Structure of the 16S rRNA methylase RmtB, I222 Descriptor: 16S rRNA methylase, S-ADENOSYL-L-HOMOCYSTEINE Authors: Schmitt, E, Galimand, M, Panvert, M, Dupechez, M, Courvalin, P, Mechulam, Y. Deposit date: 2009-01-08 Release date: 2009-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases J.Mol.Biol., 388, 2009
7F9U	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Halofuginone Descriptor: 4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, BROMIDE ION, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-07-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: TgPRS with double inhibitors To Be Published
7F9R	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L95, L-Proline and Febrifugine Descriptor: 1,2-ETHANEDIOL, 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, CHLORIDE ION, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-07-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.83 Å) Cite: TgPRS with double inhibitors To Be Published
7F9V	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Halofuginone Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-07-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.816 Å) Cite: TgPRS with double inhibitors To Be Published
7F9T	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and Halofuginone Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, ... Authors: Malhotra, N, Manickam, Y, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-10-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.489 Å) Cite: TgPRS with double inhibitors To Be Published
7F9P	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L95 and azetidine Descriptor: (2S)-azetidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-10-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.57 Å) Cite: TgPRS with double inhibitors To Be Published
7F9S	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Febrifugine (FF) Descriptor: 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, 4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, BETA-MERCAPTOETHANOL, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-10-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.861 Å) Cite: TgPRS with double inhibitors To Be Published
7F9Q	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and Febrifugine Descriptor: 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CALCIUM ION, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-07-04 Release date: 2022-10-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.796 Å) Cite: TgPRS with double inhibitors To Be Published
1Q0L	Crystal structure of DXR in complex with fosmidomycin Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Mac Sweeney, A, Lange, R, D'Arcy, A, Douangamath, A, Surivet, J.-P, Oefner, C. Deposit date: 2003-07-16 Release date: 2004-07-20 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.65 Å) Cite: The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation. J.Mol.Biol., 345, 2005
1Q0H	Crystal structure of selenomethionine-labelled DXR in complex with fosmidomycin Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, CITRIC ACID, ... Authors: Mac Sweeney, A, Lange, R, D'Arcy, A, Douangamath, A, Surivet, J.-P, Oefner, C. Deposit date: 2003-07-16 Release date: 2004-07-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation. J.Mol.Biol., 345, 2005
7EAF	Crystal structure of SAM-I riboswitch with the Actinomyces-1 k-turn Descriptor: BARIUM ION, RNA (94-MER), S-ADENOSYLMETHIONINE, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2021-03-07 Release date: 2021-06-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structure and folding of four putative kink turns identified in structured RNA species in a test of structural prediction rules. Nucleic Acids Res., 49, 2021

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