7F9P

Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L95 and azetidine

Summary for 7F9P

• Entry DOI: 10.2210/pdb7f9p/pdb
• Descriptor: Prolyl-tRNA synthetase (ProRS), ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide, (2S)-azetidine-2-carboxylic acid, ... (6 entities in total)
• Functional Keywords: protein translation, inhibitor, prs, atp pocket, double drug, ligase
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 1
• Total formula weight: 59228.72

Authors

Manickam, Y.,Malhotra, N.,Sharma, A. (deposition date: 2021-07-04, release date: 2022-10-05, Last modification date: 2023-11-29)

• Primary citation: Malhotra, N.,Manickam, Y.,Sharma, A.; TgPRS with double inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)