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7RNS
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BU of 7rns by Molmil
nSH2 domain of p85-alpha subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
Descriptor: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
Authors:Dai, S, Horton, J.R, Cheng, X.
Deposit date:2021-07-29
Release date:2021-08-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
7RNU
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BU of 7rnu by Molmil
nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
Descriptor: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
Authors:Dai, S, Horton, J.R, Cheng, X.
Deposit date:2021-07-29
Release date:2021-08-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
3LK4
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BU of 3lk4 by Molmil
Crystal structure of CapZ bound to the uncapping motif from CD2AP
Descriptor: CD2-associated protein, F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2
Authors:Hernandez-Valladares, M, Kim, T, Kannan, B, Tung, A, Cooper, J.A, Robinson, R.C.
Deposit date:2010-01-27
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural characterization of a capping protein interaction motif defines a family of actin filament regulators.
Nat.Struct.Mol.Biol., 17, 2010
2D1L
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BU of 2d1l by Molmil
Structure of F-actin binding domain IMD of MIM (Missing In Metastasis)
Descriptor: Metastasis suppressor protein 1
Authors:Lee, S.H, Kerff, F, Chereau, D, Ferron, F, Dominguez, R.
Deposit date:2005-08-27
Release date:2006-09-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for the actin-binding function of missing-in-metastasis
Structure, 15, 2007
6DUW
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BU of 6duw by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Descriptor: Catenin alpha-2
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
6DV1
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BU of 6dv1 by Molmil
Crystal structure of the alpha-E-catenin actin-binding domain
Descriptor: BROMIDE ION, Catenin alpha-1, SULFATE ION
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
6DUY
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BU of 6duy by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Descriptor: Catenin alpha-2
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
8COG
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BU of 8cog by Molmil
Human arginylated beta-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Pinto, C.S, Bakker, S.E, Suchenko, A, Hussain, H, Hatano, T, Sampath, K, Chinthalapudi, K, Mishima, M, Balasubramanian, M.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.499 Å)
Cite:Structure and physiological investigation of human arginylated beta-actin
To Be Published
6SL7
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BU of 6sl7 by Molmil
The Delta Calcium mutant of ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA
Descriptor: Calponin homology domain protein putative
Authors:Pinotsis, N, Lopez Arolas, A, Djinovic-Carugo, K.
Deposit date:2019-08-18
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin.
Proc.Natl.Acad.Sci.USA, 117, 2020
3JBH
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BU of 3jbh by Molmil
TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS
Descriptor: MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE
Authors:Alamo, L, Qi, D, Wriggers, W, Pinto, A, Zhu, J, Bilbao, A, Gillilan, R.E, Hu, S, Padron, R.
Deposit date:2015-09-01
Release date:2016-03-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
J. Mol. Biol., 428, 2016
3AAE
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BU of 3aae by Molmil
Crystal structure of Actin capping protein in complex with CARMIL fragment
Descriptor: 32mer peptide from Leucine-rich repeat-containing protein 16A, F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2
Authors:Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y.
Deposit date:2009-11-16
Release date:2010-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Two distinct mechanisms for the regulation of actin capping protein-competitive or allosteric inhibitions
To be Published
3UKR
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BU of 3ukr by Molmil
Crystal structure of Bos taurus Arp2/3 complex with bound inhibitor CK-666
Descriptor: 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:Nolen, B.J, Han, M.
Deposit date:2011-11-09
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton.
Chemmedchem, 7, 2012
7Z8K
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BU of 7z8k by Molmil
Cytoplasmic dynein (A1) bound to BICDR1
Descriptor: ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, Cytoplasmic dynein 1 heavy chain 1, ...
Authors:Chaaban, S, Carter, A.P.
Deposit date:2022-03-17
Release date:2022-07-27
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (4.37 Å)
Cite:Structure of dynein-dynactin on microtubules shows tandem adaptor binding.
Nature, 610, 2022
6JCU
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BU of 6jcu by Molmil
Crystal structure of an actin monomer in complex with a nucleator Cordon-Bleu WH2-motif peptide mutant. T22V, H11R
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Scipion, C.P.M, Robinson, R.C.
Deposit date:2019-01-30
Release date:2020-02-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Design of an actin-severing peptide.
To Be Published
6JBK
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BU of 6jbk by Molmil
Crystal structure of an actin monomer in complex with the nucleator Cordon-Bleu WH2-motif peptide mutant. T22V
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Scipion, C.P.M, Robinson, R.C.
Deposit date:2019-01-25
Release date:2020-02-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Design of an actin-severing peptide
To Be Published
1KSR
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BU of 1ksr by Molmil
THE REPEATING SEGMENTS OF THE F-ACTIN CROSS-LINKING GELATION FACTOR (ABP-120) HAVE AN IMMUNOGLOBULIN FOLD, NMR, 20 STRUCTURES
Descriptor: GELATION FACTOR
Authors:Fucini, P, Renner, C, Herberhold, C, Noegel, A.A, Holak, T.A.
Deposit date:1997-02-07
Release date:1997-08-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold.
Nat.Struct.Biol., 4, 1997
6JH9
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BU of 6jh9 by Molmil
Crystal structure of an actin monomer in complex with a chimeric peptide of Cordon-Bleu WH2 mutant and MIM. Lys18Arg
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Scipion, C.P.M, Robinson, R.C.
Deposit date:2019-02-17
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.739 Å)
Cite:Design of an actin-severing peptide.
To Be Published
6JH8
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BU of 6jh8 by Molmil
Crystal structure of an actin monomer in complex with a chimeric peptide of Cordon-Bleu WH2 mutant and MIM.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Scipion, C.P.M, Robinson, R.C.
Deposit date:2019-02-17
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.149 Å)
Cite:Design of an actin-severing peptide.
To Be Published
2P9S
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BU of 2p9s by Molmil
Structure of bovine Arp2/3 complex co-crystallized with ATP/Mg2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
Authors:Nolen, B.J, Pollard, T.D.
Deposit date:2007-03-26
Release date:2007-05-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2P9I
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BU of 2p9i by Molmil
Crystal Structure of bovine Arp2/3 Complex co-crystallized with ADP and crosslinked with gluteraldehyde
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
Authors:Nolen, B.J, Pollard, T.D.
Deposit date:2007-03-26
Release date:2007-05-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2P9K
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BU of 2p9k by Molmil
Crystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
Authors:Nolen, B.J, Pollard, T.D.
Deposit date:2007-03-26
Release date:2007-05-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
7UTI
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BU of 7uti by Molmil
ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM BOUND STATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rynkiewicz, M.J, Pavadai, E, Lehman, W.
Deposit date:2022-04-27
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments.
Biophys J, 119, 2020
7UTL
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BU of 7utl by Molmil
ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM FREE STATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rynkiewicz, M.J, Pavadai, E, Lehman, W.
Deposit date:2022-04-27
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments.
Biophys J, 119, 2020
2P9P
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BU of 2p9p by Molmil
Crystal Structure of bovine Arp2/3 complex co-crystallized with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
Authors:Nolen, B.J, Pollard, T.D.
Deposit date:2007-03-26
Release date:2007-05-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2WA6
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BU of 2wa6 by Molmil
Structure of the W148R mutant of human filamin b actin binding domain at 1.95 Angstrom resolution
Descriptor: CARBONATE ION, FILAMIN-B
Authors:Sawyer, G.M, Clark, A.R, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-02-03
Release date:2009-06-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains.
J.Mol.Biol., 390, 2009

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