PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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3CRQ	Structure of tRNA Dimethylallyltransferase: RNA Modification through a Channel Descriptor: DIPHOSPHATE, MAGNESIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase Authors: Huang, R.H, Xie, W, Zhou, C. Deposit date: 2008-04-07 Release date: 2008-04-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of tRNA Dimethylallyltransferase: RNA Modification through a Channel J.Mol.Biol., 367, 2007
7BPF	Structure of L-threoninol nucleic acid - RNA complex Descriptor: L-aTNA (3'-(*GP*CP*AP*GP*CP*AP*GP*C)-1'), RNA (5'-R(*GP*CP*UP*GP*CP*(5BU)P*GP*C)-3') Authors: Kamiya, Y, Satoh, T, Kodama, A, Suzuki, T, Uchiyama, S, Kato, K, Asanuma, H. Deposit date: 2020-03-22 Release date: 2020-11-25 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Intrastrand backbone-nucleobase interactions stabilize unwound right-handed helical structures of heteroduplexes of L-aTNA/RNA and SNA/RNA Commun Chem, 2020
6Q4B	CDK2 in complex with FragLite13 Descriptor: 5-bromanylpyrimidine, Cyclin-dependent kinase 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.12 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4J	CDK2 in complex with FragLite34 Descriptor: 2-[3-(pyrimidin-4-ylamino)phenyl]ethanoic acid, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.05 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
7BPG	Structure of serinol nucleic acid - RNA complex Descriptor: CALCIUM ION, RNA (5'-R(*GP*CP*UP*GP*CP*(5BU)P*GP*C)-3'), SNA (S-(F7R)(F7X)(F7O)(F7R)(F7X)(F7O)(F7R)(F7U)-R) Authors: Kamiya, Y, Satoh, T, Kodama, A, Suzuki, T, Uchiyama, S, Kato, K, Asanuma, H. Deposit date: 2020-03-22 Release date: 2020-11-25 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Intrastrand backbone-nucleobase interactions stabilize unwound right-handed helical structures of heteroduplexes of L-aTNA/RNA and SNA/RNA Commun Chem, 2020
6Q3B	CDK2 in complex with FragLite2 Descriptor: 4-IODOPYRAZOLE, Cyclin-dependent kinase 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-04 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.11 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q49	CDK2 in complex with FragLite6 Descriptor: 4-bromanyl-1~{H}-pyridin-2-one, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q3C	CDK2 in complex with FragLite1 Descriptor: 4-bromo-1H-pyrazole, Cyclin-dependent kinase 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-04 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.29 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4G	CDK2 in complex with FragLite37 Descriptor: 2-[3-(2-azanyl-9~{H}-purin-6-yl)phenyl]ethanoic acid, Cyclin-dependent kinase 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (0.98 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
3QJL	One RAMP protein binding different RNA substrates Descriptor: Putative uncharacterized protein PH0350, RNA (5'-R(*GP*UP*UP*AP*CP*AP*AP*UP*AP*AP*GP*A)-3') Authors: Wang, R, Zheng, H, Preamplume, G, Li, H. Deposit date: 2011-01-30 Release date: 2012-02-08 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.7009 Å) Cite: Cooperative and Specific Binding of a RAMP Protein to Single-stranded CRISPR Repeat RNA To be Published
6Q48	CDK2 in complex with FragLite7 Descriptor: 4-iodanyl-3~{H}-pyridin-2-one, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.03 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4H	CDK2 in complex with FragLite36 Descriptor: 2-[3-[(2-azanyl-9~{H}-purin-6-yl)oxy]phenyl]ethanoic acid, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
3C44	Crystal structure of HIV-1 subtype F DIS extended duplex RNA bound to paromomycin Descriptor: CHLORIDE ION, HIV-1 subtype F genomic RNA, PAROMOMYCIN, ... Authors: Freisz, S, Ennifar, E, Dumas, P. Deposit date: 2008-01-29 Release date: 2008-05-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site. Angew.Chem.Int.Ed.Engl., 47, 2008
6Q4C	CDK2 in complex with FragLite16 Descriptor: 4-bromanyl-1,8-naphthyridine, Cyclin-dependent kinase 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.73 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4F	CDK2 in complex with FragLite32 Descriptor: Cyclin-dependent kinase 2, PYRIDINE-2,6-DIAMINE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.21 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4A	CDK2 in complex with FragLite14 Descriptor: 5-iodanylpyrimidine, CYCLIN-DEPENDENT KINASE 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.13 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4I	CDK2 in complex with FragLite35 Descriptor: 2-[4-[(2-oxidanylidene-3~{H}-pyridin-4-yl)oxy]phenyl]ethanoic acid, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.11 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4E	CDK2 in complex with FragLite33 Descriptor: 6-iodanyl-7~{H}-purin-2-amine, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.06 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4K	CDK2 in complex with FragLite38 Descriptor: (~{E})-3-[3-[(4-chlorophenyl)carbamoyl]phenyl]prop-2-enoic acid, 1,2-ETHANEDIOL, Cyclin-dependent kinase 2 Authors: Wood, D.J, Martin, M.P, Noble, M.E.M. Deposit date: 2018-12-05 Release date: 2019-03-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.06 Å) Cite: FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
3C7R	Crystal Structure of HIV-1 subtype F DIS extended duplex RNA bound to neomycin Descriptor: HIV-1 subtype F genomic RNA, NEOMYCIN, POTASSIUM ION Authors: Freisz, S, Lang, K, Micura, R, Dumas, P, Ennifar, E. Deposit date: 2008-02-08 Release date: 2008-05-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site. Angew.Chem.Int.Ed.Engl., 47, 2008
4RPT	The 1.35A structure of a viral RNase L antagonist reveals basis for the 2'-5'-oligoadenylate binding and enzyme activity. Descriptor: 1,2-ETHANEDIOL, Capping enzyme protein, MALONATE ION Authors: Hu, L, Prasad, B.V.V. Deposit date: 2014-10-31 Release date: 2015-04-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist. J.Virol., 89, 2015
3C5D	Crystal structure of HIV-1 subtype F DIS extended duplex RNA bound to lividomycin Descriptor: 'HIV-1 subtype F genomic RNA, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, POTASSIUM ION Authors: Freisz, S, Lang, K, Micura, R, Dumas, P, Ennifar, E. Deposit date: 2008-01-31 Release date: 2008-05-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site. Angew.Chem.Int.Ed.Engl., 47, 2008
1WWG	NMR Structure Determined for MLV NC Complex with RNA Sequence UAUCUG Descriptor: 5'-R(P*UP*AP*UP*CP*UP*G)-3', Nucleoprotein p10, ZINC ION Authors: Dey, A, York, D, Smalls-Mantey, A, Summers, M.F. Deposit date: 2005-01-05 Release date: 2005-04-05 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Composition and sequence-dependent binding of RNA to the nucleocapsid protein of Moloney murine leukemia virus(,) Biochemistry, 44, 2005
1I6V	THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX Descriptor: DNA-DIRECTED RNA POLYMERASE, MAGNESIUM ION, RIFAMPICIN, ... Authors: Campbell, E.A, Korzheva, N, Mustaev, A, Murakami, K, Goldfarb, A, Darst, S.A. Deposit date: 2001-03-05 Release date: 2001-04-18 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural mechanism for rifampicin inhibition of bacterial rna polymerase. Cell(Cambridge,Mass.), 104, 2001
1WWF	NMR Structure Determined for MLV NC Complex with RNA Sequence CCUCCGU Descriptor: 5'-R(P*CP*CP*UP*CP*CP*GP*U)-3', Nucleoprotein p10, ZINC ION Authors: Dey, A, York, D, Smalls-Mantey, A, Summers, M.F. Deposit date: 2005-01-05 Release date: 2005-04-05 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Composition and sequence-dependent binding of RNA to the nucleocapsid protein of Moloney murine leukemia virus(,) Biochemistry, 44, 2005

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