7XLL
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8AHW
| Structure of DCS-resistant variant D322N of alanine racemase from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, Alanine racemase, GLYCEROL | Authors: | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | Deposit date: | 2022-07-22 | Release date: | 2023-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis . Acs Bio Med Chem Au, 3, 2023
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8B8H
| Structure of DCS-resistant variant D322N of alanine racemase from M. tuberculosis in complex with DCS | Descriptor: | (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, Alanine racemase, ... | Authors: | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | Deposit date: | 2022-10-04 | Release date: | 2023-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis . Acs Bio Med Chem Au, 3, 2023
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1L6G
| Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine | Descriptor: | N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE, alanine racemase | Authors: | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | Deposit date: | 2002-03-10 | Release date: | 2002-06-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine. J.Biol.Chem., 277, 2002
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4ILS
| Crystal structure of engineered protein. northeast structural genomics Consortium target or117 | Descriptor: | Engineered protein | Authors: | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-12-31 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of engineered protein. northeast structural genomics Consortium target or117 To be Published
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1L6F
| Alanine racemase bound with N-(5'-phosphopyridoxyl)-L-alanine | Descriptor: | ALANYL-PYRIDOXAL-5'-PHOSPHATE, alanine racemase | Authors: | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | Deposit date: | 2002-03-09 | Release date: | 2002-06-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine. J.Biol.Chem., 277, 2002
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5FAG
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5FAC
| Alanine Racemase from Streptomyces coelicolor A3(2) | Descriptor: | Alanine racemase, CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE | Authors: | Tassoni, R, Pannu, N.S. | Deposit date: | 2015-12-11 | Release date: | 2016-12-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional characterization of the alanine racemase from Streptomyces coelicolor A3(2). Biochem. Biophys. Res. Commun., 483, 2017
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3OO2
| 2.37 Angstrom resolution crystal structure of an alanine racemase (alr) from Staphylococcus aureus subsp. aureus COL | Descriptor: | Alanine racemase 1, BETA-MERCAPTOETHANOL, PHOSPHATE ION, ... | Authors: | Halavaty, A.S, Shuvalova, L, Minasov, G, Winsor, J, Dubrovska, I, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-08-30 | Release date: | 2010-10-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | 2.37 Angstrom resolution crystal structure of an alanine racemase (alr) from Staphylococcus aureus subsp. aureus COL TO BE PUBLISHED
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3HA1
| Alanine racemase from Bacillus Anthracis (Ames) | Descriptor: | ACETATE ION, Alanine racemase, CHLORIDE ION | Authors: | Counago, R.M, Davlieva, M, Strych, U, Hill, R.E, Krause, K.L. | Deposit date: | 2009-04-30 | Release date: | 2009-09-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames). Bmc Struct.Biol., 9, 2009
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1XQL
| Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase | Descriptor: | (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Fenn, T.D, Holyoak, T, Stamper, G.F, Ringe, D. | Deposit date: | 2004-10-12 | Release date: | 2005-01-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase Biochemistry, 44, 2005
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1XQK
| Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase | Descriptor: | (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Alanine racemase | Authors: | Fenn, T.D, Holyoak, T, Stamper, G.F, Ringe, D. | Deposit date: | 2004-10-12 | Release date: | 2005-01-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase Biochemistry, 44, 2005
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4WR3
| Y274F alanine racemase from E. coli | Descriptor: | Alanine racemase, biosynthetic, GLYCEROL, ... | Authors: | Squire, C.J, Yosaatmadja, Y, Patrick, W.M. | Deposit date: | 2014-10-23 | Release date: | 2015-11-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes. J.Biol.Chem., 291, 2016
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3HUR
| Crystal structure of alanine racemase from Oenococcus oeni | Descriptor: | Alanine racemase, SULFATE ION | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Hu, S, Romero, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-06-15 | Release date: | 2009-07-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of alanine racemase from Oenococcus oeni To be Published
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4XBJ
| Y274F alanine racemase from E. coli inhibited by l-ala-p | Descriptor: | Alanine racemase, biosynthetic, SULFATE ION, ... | Authors: | Squire, C.J, Yosaatmadja, Y, Patrick, W.M. | Deposit date: | 2014-12-17 | Release date: | 2015-12-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes. J.Biol.Chem., 291, 2016
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3S46
| The crystal structure of alanine racemase from streptococcus pneumoniae | Descriptor: | Alanine racemase, BENZOIC ACID | Authors: | Im, H, Sharpe, M.L, Strych, U, Davlieva, M, Krause, K.L. | Deposit date: | 2011-05-18 | Release date: | 2011-06-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design. BMC MICROBIOL., 11, 2011
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6G58
| Structure of the alanine racemase from Staphylococcus aureus in complex with a pyridoxal 5' phosphate-derivative | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, (6-but-3-ynyl-4-methyl-5-oxidanyl-pyridin-3-yl)methyl dihydrogen phosphate, ... | Authors: | Hoegl, A, Sieber, S.A, Schneider, S. | Deposit date: | 2018-03-29 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics. Nat Chem, 10, 2018
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5ZL6
| Histidine Racemase from Leuconostoc mesenteroides subsp. sake NBRC 102480 | Descriptor: | Histidine racemase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Adachi, M, Shimizu, R, Oikawa, T. | Deposit date: | 2018-03-27 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The first identification and characterization of a histidine-specific amino acid racemase, histidine racemase from a lactic acid bacterium, Leuconostoc mesenteroides subsp. sake NBRC 102480. Amino Acids, 51, 2019
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5YYC
| Crystal structure of alanine racemase from Bacillus pseudofirmus (OF4) | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Dong, H, Hu, T.T, He, G.Z, Lu, D.R, Qi, J.X, Dou, Y.S, Long, W, He, X, Su, D, Ju, J.S. | Deposit date: | 2017-12-08 | Release date: | 2019-01-02 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural features and kinetic characterization of alanine racemase from Bacillus pseudofirmus OF4. Biochem. Biophys. Res. Commun., 497, 2018
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6G59
| Structure of the alanine racemase from Staphylococcus aureus in complex with an pyridoxal-6- phosphate derivative | Descriptor: | (6-ethynyl-4-methanoyl-5-oxidanyl-pyridin-3-yl)methyl dihydrogen phosphate, Alanine racemase 1, CHLORIDE ION, ... | Authors: | Hoegl, A, Sieber, S.A, Schneider, S. | Deposit date: | 2018-03-29 | Release date: | 2018-05-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics. Nat Chem, 10, 2018
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6A2F
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1XFC
| The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | Authors: | LeMagueres, P, Im, H, Ebalunode, J, Strych, U, Benedik, M.J, Briggs, J.M, Kohn, H, Krause, K.L. | Deposit date: | 2004-09-14 | Release date: | 2005-08-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry, 44, 2005
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6G56
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3E6E
| Crystal structure of Alanine racemase from E.faecalis complex with cycloserine | Descriptor: | Alanine racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | Authors: | Hwang, K.Y, Priyadarshi, A, Lee, E.H, Sung, M.W. | Deposit date: | 2008-08-15 | Release date: | 2009-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into the alanine racemase from Enterococcus faecalis. Biochim.Biophys.Acta, 1794, 2009
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6Q70
| Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis in the presence of HEPES | Descriptor: | Alanine racemase 2, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Bernardo-Garcia, N, Gago, F, Hermoso, J.A. | Deposit date: | 2018-12-12 | Release date: | 2019-04-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase. Org.Biomol.Chem., 17, 2019
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