3Q2N
| Mouse E-cadherin EC1-2 L175D mutant | Descriptor: | CALCIUM ION, Cadherin-1, TETRAETHYLENE GLYCOL | Authors: | Harrison, O.J, Jin, X, Shapiro, L. | Deposit date: | 2010-12-20 | Release date: | 2011-02-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure, 19, 2011
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3PPE
| Crystal structure of chicken VE-cadherin EC1-2 | Descriptor: | CALCIUM ION, Vascular endothelial cadherin | Authors: | Brasch, J, Harrison, O.J, Ahlsen, G, Carnally, S.M, Henderson, R.M, Honig, B, Shapiro, L.S. | Deposit date: | 2010-11-24 | Release date: | 2011-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and binding mechanism of vascular endothelial cadherin: a divergent classical cadherin. J.Mol.Biol., 408, 2011
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3Q2L
| Mouse E-cadherin EC1-2 V81D mutant | Descriptor: | CALCIUM ION, Cadherin-1, PENTAETHYLENE GLYCOL | Authors: | Harrison, O.J, Jin, X, Shapiro, L. | Deposit date: | 2010-12-20 | Release date: | 2011-02-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure, 19, 2011
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3Q2V
| Crystal structure of mouse E-cadherin ectodomain | Descriptor: | CALCIUM ION, Cadherin-1, MANGANESE (II) ION, ... | Authors: | Jin, X, Harrison, O.J, Shapiro, L. | Deposit date: | 2010-12-20 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure, 19, 2011
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3Q2W
| Crystal structure of mouse N-cadherin ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Jin, X, Shapiro, L. | Deposit date: | 2010-12-20 | Release date: | 2011-02-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure, 19, 2011
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7A7D
| Cadherin fit into cryo-ET map | Descriptor: | Desmocollin-2, Desmoglein-2 | Authors: | Sikora, M, Ermel, U.H, Seybold, A, Kunz, M, Calloni, G, Reitz, J, Vabulas, R.M, Hummer, G, Frangakis, A.S. | Deposit date: | 2020-08-28 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (26 Å) | Cite: | Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZTB
| Crystal Structure of human P-Cadherin EC1_EC2 | Descriptor: | CALCIUM ION, Cadherin-3, SODIUM ION | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-17 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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6ZTR
| Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324) | Descriptor: | CALCIUM ION, CQY684 Fab heavy-chain, CQY684 Fab light-chain, ... | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-20 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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7UQU
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3QRB
| crystal structure of E-cadherin EC1-2 P5A P6A | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cadherin-1, ... | Authors: | Jin, X, Shapiro, L. | Deposit date: | 2011-02-17 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular design principles underlying beta-strand swapping in the adhesive dimerization of cadherins. Nat.Struct.Mol.Biol., 18, 2011
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4NUM
| Crystal structure of mouse N-cadherin EC1-2 A78SI92M | Descriptor: | CALCIUM ION, Cadherin-2 | Authors: | Jin, X. | Deposit date: | 2013-12-03 | Release date: | 2014-09-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
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4NUQ
| Crystal structure of mouse N-cadherin EC1-2 W2F | Descriptor: | CALCIUM ION, Cadherin-2 | Authors: | Jin, X. | Deposit date: | 2013-12-03 | Release date: | 2014-09-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.116 Å) | Cite: | Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
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1NCG
| STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS | Descriptor: | N-CADHERIN, YTTERBIUM (III) ION | Authors: | Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A. | Deposit date: | 1995-03-23 | Release date: | 1995-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of cell-cell adhesion by cadherins. Nature, 374, 1995
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1NCI
| STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS | Descriptor: | N-CADHERIN, URANYL (VI) ION | Authors: | Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A. | Deposit date: | 1995-03-23 | Release date: | 1995-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of cell-cell adhesion by cadherins. Nature, 374, 1995
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1Q1P
| E-Cadherin activation | Descriptor: | CALCIUM ION, Epithelial-cadherin | Authors: | Haussinger, D, Stetefeld, J. | Deposit date: | 2003-07-22 | Release date: | 2004-04-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography. Embo J., 23, 2004
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2QVF
| mouse E-cadherin domains 1,2 | Descriptor: | CALCIUM ION, Epithelial-cadherin (E-cadherin) (Uvomorulin) (Cadherin-1) (ARC-1) (CD324 antigen) | Authors: | Carroll, K.J. | Deposit date: | 2007-08-08 | Release date: | 2008-08-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | E-cadherin domains 1,2 To be Published
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2QVI
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3LNE
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3LNF
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3LNI
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3LNH
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3LND
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3LNG
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3K5S
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2O72
| Crystal Structure Analysis of human E-cadherin (1-213) | Descriptor: | CALCIUM ION, Epithelial-cadherin | Authors: | Parisini, E, Wang, J.-H. | Deposit date: | 2006-12-09 | Release date: | 2007-10-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism J.Mol.Biol., 373, 2007
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