PDB: 66478 resultsInfo pagesStatus searchChemie searchBIRD

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3BW2	Crystal structures and site-directed mutagenesis study of nitroalkane oxidase from Streptomyces ansochromogenes Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-nitropropane dioxygenase, FLAVIN MONONUCLEOTIDE Authors: Li, Y.H, Gao, Z.Q, Hou, H.F. Deposit date: 2008-01-08 Release date: 2009-01-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure and site-directed mutagenesis of a nitroalkane oxidase from Streptomyces ansochromogenes Biochem.Biophys.Res.Commun., 405, 2011
4MBI	Discovery of Pyrazolo[1,5a]pyrimidine-based Pim1 Inhibitors Descriptor: N,N-dimethyl-N'-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]ethane-1,2-diamine, Serine/threonine-protein kinase pim-1 Authors: Azevedo, R, Fischmann, T.O. Deposit date: 2013-08-19 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: A template-based approach. Bioorg.Med.Chem.Lett., 23, 2013
4M4U	Structural evaluation D84A mutant of the aspergillus fumigatus kdnase (sialidase) Descriptor: CHLORIDE ION, Extracellular sialidase/neuraminidase, putative, ... Authors: Telford, J.C, Taylor, G.L. Deposit date: 2013-08-07 Release date: 2014-09-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Active site mutants of a fungal KDNase To be Published
3BZN	Crystal Structure of Open form of Menaquinone-Specific Isochorismate Synthase, MenF Descriptor: MAGNESIUM ION, Menaquinone-specific isochorismate synthase, SULFATE ION Authors: Parsons, J.F, Shi, K.M, Ladner, J.E. Deposit date: 2008-01-18 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of isochorismate synthase in complex with magnesium. Acta Crystallogr.,Sect.D, 64, 2008
3MD0	Crystal structure of arginine/ornithine transport system ATPase from Mycobacterium tuberculosis bound to GDP (a RAS-like GTPase superfamily protein) Descriptor: Arginine/ornithine transport system ATPase, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-03-29 Release date: 2010-04-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. J.Struct.Funct.Genom., 16, 2015
3MGZ	Crystal structure of DHBPS domain of bi-functional DHBPS/GTP cyclohydrolase II from Mycobacterium tuberculosis at pH 4.0 Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION Authors: Singh, M, Kumar, P, Karthikeyan, S. Deposit date: 2010-04-07 Release date: 2011-02-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis J.Struct.Biol., 174, 2011
3MK5	Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from Mycobacterium tuberculosis with sulfate and zinc at pH 4.00 Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION, ZINC ION Authors: Singh, M, Karthikeyan, S. Deposit date: 2010-04-14 Release date: 2011-02-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis J.Struct.Biol., 174, 2011
4NJO	crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in Entamoeba histolytica Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-3-phosphoglycerate dehydrogenase, putative, ... Authors: Singh, R.K, Gourinath, S. Deposit date: 2013-11-11 Release date: 2014-10-08 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine. Febs J., 281, 2014
2ZMD	Crystal structure of human Mps1 catalytic domain T686A mutant in complex with SP600125 inhibitor Descriptor: 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Dual specificity protein kinase TTK Authors: Chu, M.L.H, Chavas, L.M.G, Douglas, K.T, Eyers, P.A, Tabernero, L. Deposit date: 2008-04-16 Release date: 2008-05-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125. J.Biol.Chem., 283, 2008
4NLZ	Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP Descriptor: 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... Authors: Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. Deposit date: 2013-11-14 Release date: 2014-01-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.683 Å) Cite: Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
3PDV	Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1 Descriptor: PDZ and LIM domain protein 2, C-teminal peptide from Nonstructural protein 1, SODIUM ION Authors: Li, X. Deposit date: 2010-10-25 Release date: 2011-09-07 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1 Plos One, 6, 2011
3PIL	Crystal structure of Mxr1 from Saccharomyces cerevisiae in reduced form Descriptor: ACETATE ION, Peptide methionine sulfoxide reductase Authors: Ma, X.X, Guo, P.C, Shi, W.W, Luo, M, Tan, X.F, Chen, Y, Zhou, C.Z. Deposit date: 2010-11-07 Release date: 2011-02-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1 J.Biol.Chem., 286, 2011
3CAF	Crystal Structure of hFGFR2 D2 Domain Descriptor: Fibroblast growth factor receptor 2 Authors: Guo, F, Dakshinamurthy, R, Kathir, K.M, Thallapuranam, S.K.K, Sakon, J. Deposit date: 2008-02-19 Release date: 2009-01-27 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Crystal structure analysis of the hFGFR2 D2 domain To be Published
3AKA	Structural basis for prokaryotic calcium-mediated regulation by a Streptomyces coelicolor calcium-binding protein Descriptor: CALCIUM ION, Putative calcium binding protein Authors: Zhao, X, Pang, H, Wang, S, Zhou, W, Yang, K, Bartlam, M. Deposit date: 2010-07-09 Release date: 2011-01-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for prokaryotic calciummediated regulation by a Streptomyces coelicolor calcium binding protein Protein Cell, 1, 2010
4N99	E. coli sliding clamp in complex with 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid Descriptor: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
3NCG	Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1 Descriptor: 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, Calmodulin-domain protein kinase 1 Authors: Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) Deposit date: 2010-06-04 Release date: 2010-07-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. ACS Med Chem Lett, 1, 2010
3ATK	Crystal structure of trypsin complexed with cycloheptanamine Descriptor: CALCIUM ION, Cationic trypsin, DIMETHYL SULFOXIDE, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2011-01-05 Release date: 2011-08-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.74 Å) Cite: In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
4NY5	X-ray structure of the adduct formed between hen egg white lysozyme and NAMI-A Descriptor: CHLORIDE ION, Lysozyme C, RUTHENIUM ION, ... Authors: Messori, L, Merlino, A. Deposit date: 2013-12-10 Release date: 2014-03-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Ruthenium metalation of proteins: the X-ray structure of the complex formed between NAMI-A and hen egg white lysozyme. Dalton Trans, 43, 2014
3PFD	Crystal structure of an Acyl-CoA dehydrogenase from Mycobacterium thermoresistibile bound to reduced flavin adenine dinucleotide solved by combined iodide ion SAD MR Descriptor: Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, IODIDE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-28 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: SAD phasing using iodide ions in a high-throughput structural genomics environment. J.STRUCT.FUNCT.GENOM., 12, 2011
4NSM	crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Collagen-like protein SclB, SULFATE ION Authors: Berisio, R, Squeglia, F, Lukomski, S, Bachert, B. Deposit date: 2013-11-28 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The Crystal Structure of the Streptococcal Collagen-like Protein 2 Globular Domain from Invasive M3-type Group A Streptococcus Shows Significant Similarity to Immunomodulatory HIV Protein gp41. J.Biol.Chem., 289, 2014
3CXR	Crystal structure of gluconate 5-dehydrogase from streptococcus suis type 2 Descriptor: Dehydrogenase with different specificities Authors: Peng, H, Gao, F, Zhang, Q, Liu, Y, Gao, G.F. Deposit date: 2008-04-25 Release date: 2009-03-17 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes. Protein Sci., 18, 2009
3PH5	Bovine beta lactoglobulin crystallized through ligandation of yttrium cations Descriptor: Beta-lactoglobulin, CHLORIDE ION, YTTRIUM (III) ION Authors: Zocher, G, Stehle, T. Deposit date: 2010-11-03 Release date: 2011-09-21 Last modified: 2014-02-19 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Novel Approach to Protein Crystallization through Ligandation of Yttrium Cations J.Appl.Crystallogr., 44, 2011
3PHO	Crystal structure of S64-4 in complex with PSBP Descriptor: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose, S64-4 Fab (IgG1) heavy chain, S64-4 Fab (IgG1) light chain Authors: Evans, D.W, Evans, S.V. Deposit date: 2010-11-04 Release date: 2011-05-18 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural insights into parallel strategies for germline antibody recognition of lipopolysaccharide from Chlamydia. Glycobiology, 21, 2011
3PH6	Bovine beta lactoglobulin crytsallized through ligandation of yttrium Descriptor: Beta-lactoglobulin, CHLORIDE ION, YTTRIUM (III) ION Authors: Zocher, G, Stehle, T. Deposit date: 2010-11-03 Release date: 2011-09-21 Last modified: 2020-01-15 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Novel Approach to Protein Crystallization through Ligandation of Yttrium Cations J.Appl.Crystallogr., 44, 2011
3PX9	RTA in complex with N-(furanylmethyl)-7-carbamoyl-pterin Descriptor: 2-amino-N-(furan-2-ylmethyl)-4-oxo-3,4-dihydropteridine-7-carboxamide, Preproricin Authors: Jasheway, K.R, Robertus, J.D. Deposit date: 2010-12-09 Release date: 2011-06-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.89 Å) Cite: 7-Substituted pterins provide a new direction for ricin A chain inhibitors. Eur.J.Med.Chem., 46, 2011

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