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7R1F
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BU of 7r1f by Molmil
Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-02-02
Release date:2022-12-28
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
5U0S
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BU of 5u0s by Molmil
Cryo-EM structure of the Mediator-RNAPII complex
Descriptor: Mediator complex subunit 10, Mediator complex subunit 11, Mediator complex subunit 14, ...
Authors:Tsai, K.-L, Yu, X, Gopalan, S, Chao, T.-C, Zhang, Y, Florens, L, Washburn, M.P, Murakami, K, Conaway, R.C, Conaway, J.W, Asturias, F.
Deposit date:2016-11-26
Release date:2017-03-08
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
7QTL
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BU of 7qtl by Molmil
Influenza A/H7N9 polymerase elongation complex
Descriptor: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-01-14
Release date:2022-12-28
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7R0E
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BU of 7r0e by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-02-01
Release date:2022-12-28
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BE0
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BU of 8be0 by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-20
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BDR
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BU of 8bdr by Molmil
Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-19
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BEK
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BU of 8bek by Molmil
Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-21
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8BF5
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BU of 8bf5 by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue
Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-10-24
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7Q5B
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BU of 7q5b by Molmil
Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene
Descriptor: DNA (19-MER), DNA (31-MER), DNA (34-MER), ...
Authors:Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A.
Deposit date:2021-11-03
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
Nat Commun, 12, 2021
6SZV
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BU of 6szv by Molmil
Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)
Descriptor: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2019-10-02
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6T0V
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BU of 6t0v by Molmil
Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)
Descriptor: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2019-10-03
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
7ZPL
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BU of 7zpl by Molmil
Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook
Descriptor: 5' vRNA, MAGNESIUM ION, Polymerase acidic protein, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2022-04-27
Release date:2022-12-28
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
8A40
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BU of 8a40 by Molmil
Structure of mammalian Pol II-TFIIS elongation complex
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P.
Deposit date:2022-06-09
Release date:2023-08-23
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
6P5J
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BU of 6p5j by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P5I
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BU of 6p5i by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2020-02-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
7TQL
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BU of 7tql by Molmil
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D.
Deposit date:2022-01-26
Release date:2022-04-27
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
6OW3
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BU of 6ow3 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-09
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.766 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6P71
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BU of 6p71 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*GP*CP*CP*GP*GP*GP*A)-3'), DNA (5'-D(P*CP*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-06-04
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OVY
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BU of 6ovy by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-08
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY7
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BU of 6oy7 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-14
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OVR
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BU of 6ovr by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-08
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.843 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY6
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BU of 6oy6 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-14
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.096 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6P5N
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BU of 6p5n by Molmil
Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-25
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P5K
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BU of 6p5k by Molmil
Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
7DKH
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BU of 7dkh by Molmil
Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex
Descriptor: Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ...
Authors:Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F.
Deposit date:2020-11-24
Release date:2021-11-24
Last modified:2022-01-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Core Module of the Yeast Paf1 Complex.
J.Mol.Biol., 434, 2021

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