8F3O
| Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Peti, W, Page, R. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3S
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F67
| Crystal structure of the refolded Penicillin Binding Protein 5 (PBP5) of Enterococcus faecium | Descriptor: | Pbp5, SULFATE ION | Authors: | D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Peti, W, Page, R. | Deposit date: | 2022-11-16 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3T
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SODIUM ION, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3Z
| Crystal structure of Penicillin Binding Protein 5 (PBP5) S422A variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3I
| Crystal structure of Penicillin Binding Protein 5 (PBP5) S466 insertion variant penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3U
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3N
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3R
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3F
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Hunashal, Y, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3P
| Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3M
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3J
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3G
| Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant in the penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8F3Q
| Crystal structure of Penicillin Binding Protein 5 (PBP5) Y460A variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Page, R, Peti, W. | Deposit date: | 2022-11-10 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics Nat Commun, 2023
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8BZH
| FC-NAc stabilizer of 14-3-3 and ERalpha | Descriptor: | 14-3-3 protein sigma, ERalpha peptide, MAGNESIUM ION, ... | Authors: | Visser, E.J, Ottmann, C. | Deposit date: | 2022-12-14 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a potential intervention strategy for endocrine resistance in breast cancer To Be Published
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8BZE
| FC-J stabilizer for ERa and 14-3-3 | Descriptor: | (2~{S},3~{R},4~{S},5~{S},6~{R})-2-[[(1~{E},3~{R},4~{S},8~{R},9~{R},10~{R},11~{S},14~{S})-14-(methoxymethyl)-3,10-dimethyl-4,9-bis(oxidanyl)-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradeca-1,6-dienyl]oxy]-6-(2-methylbut-3-en-2-yloxymethyl)oxane-3,4,5-triol, 14-3-3 protein sigma, ERalpha peptide, ... | Authors: | Visser, E.J, Ottmann, C. | Deposit date: | 2022-12-14 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a new potential intervention strategy for endocrine resistance in breast cancer To Be Published
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8BZT
| FC-NAg stabilizer of 14-3-3 and ERalpha | Descriptor: | 14-3-3 protein sigma, ERalpha peptide, MAGNESIUM ION, ... | Authors: | Visser, E.J, Ottmann, C. | Deposit date: | 2022-12-15 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a potential intervention strategy for endocrine resistance in breast cancer To Be Published
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7ZLJ
| Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and acceptor peptide, bound to CMT2-Fab and anti-Fab nanobody | Descriptor: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | Authors: | Bloch, J.S, Mao, R, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | Deposit date: | 2022-04-15 | Release date: | 2023-01-11 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nat.Chem.Biol., 19, 2023
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7ZLI
| Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody | Descriptor: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | Authors: | Bloch, J.S, Mukherjee, S, Boilevin, J, Irobalieva, R, Darbre, T, Reymond, J.L, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | Deposit date: | 2022-04-15 | Release date: | 2023-01-11 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nat.Chem.Biol., 19, 2023
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8F3W
| Crystal structure of Penicillin Binding Protein 5 (PBP5) PAPAPAP variant penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R. | Deposit date: | 2022-11-10 | Release date: | 2023-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam antibiotics To Be Published
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8F3X
| Crystal structure of Penicillin Binding Protein 5 (PBP5) Poly-Gly variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R. | Deposit date: | 2022-11-10 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam antibiotics To Be Published
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8F3Y
| Crystal structure of Penicillin Binding Protein 5 (PBP5) Poly-Gly variant penicillin bound form from Enterococcus faecium | Descriptor: | OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION | Authors: | Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R. | Deposit date: | 2022-11-10 | Release date: | 2023-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam antibiotics To Be Published
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8F3V
| Crystal structure of Penicillin Binding Protein 5 (PBP5) PAPAPAP variant apo form from Enterococcus faecium | Descriptor: | Penicillin binding protein 5, SULFATE ION | Authors: | Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R. | Deposit date: | 2022-11-10 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam antibiotics To Be Published
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8PMX
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