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8BZH

FC-NAc stabilizer of 14-3-3 and ERalpha

Summary for 8BZH
Entry DOI10.2210/pdb8bzh/pdb
Descriptor14-3-3 protein sigma, ERalpha peptide, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords14-3-3, stabilization, eralpha, fusicoccin, structural protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight27867.23
Authors
Visser, E.J.,Ottmann, C. (deposition date: 2022-12-14, release date: 2024-06-26)
Primary citationVisser, E.J.,Donaldson Collier, M.,Siefert, J.,Konstantinidou, M.,Paul, S.,Cossar, P.,Miley, G.,Meijer, O.,Arkin, M.R.,Ottmann, C.,Zwart, W.,Brunsveld, L.
Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a potential intervention strategy for endocrine resistance in breast cancer
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.46 Å)
Structure validation

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PDB entries from 2024-11-06

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