8BZH
FC-NAc stabilizer of 14-3-3 and ERalpha
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
2 | B | ERalpha peptide | polymer | 5 | 613.6 | 1 | UniProt (by SIFTS) (P03372) In PDB | Homo sapiens | |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
4 | A | ~{N}-[(2~{S})-2-[(1~{E},3~{R},4~{S},8~{R},9~{R},10~{R},11~{S},14~{S})-14-(methoxymethyl)-3,10-dimethyl-8-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(2-methylbut-3-en-2-yloxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,9-bis(oxidanyl)-6-tricyclo[9.3.0.0^{3,7}]tetradeca-1,6-dienyl]propyl]ethanamide | non-polymer | 637.8 | 1 | Chemie (EZ5) | |||
5 | water | water | 18.0 | 283 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27156.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 710.7 | |
All* | Total formula weight | 27867.2 |