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1VVJ
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BU of 1vvj by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Maehigashi, T, Dunkle, J.A, Dunham, C.M.
Deposit date:2013-05-24
Release date:2014-08-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.440001 Å)
Cite:Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
8OIV
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BU of 8oiv by Molmil
Monkeypox virus VP39 in complex with SAH and cap0
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Skvara, P, Chalupska, D, Silhan, J, Klima, M, Boura, E.
Deposit date:2023-03-23
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Res., 216, 2023
6DU4
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BU of 6du4 by Molmil
Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, ...
Authors:Doxtader, K, Wang, P, Nam, Y.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
Mol. Cell, 71, 2018
6TRQ
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BU of 6trq by Molmil
S.c. Scavenger Decapping Enzyme DcpS in complex with the capped RNA dinucleotide m7G-GU
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, L-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHONATE, ...
Authors:Fuchs, A.-L, Neu, A, Sprangers, R.
Deposit date:2019-12-19
Release date:2020-07-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.944 Å)
Cite:Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme.
Proc.Natl.Acad.Sci.USA, 117, 2020
4WFM
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BU of 4wfm by Molmil
Structure of the complete bacterial SRP Alu domain
Descriptor: Bacillus subtilis small cytoplasmic RNA (scRNA),RNA, COBALT HEXAMMINE(III), MAGNESIUM ION
Authors:Kempf, G, Wild, K, Sinning, I.
Deposit date:2014-09-15
Release date:2014-10-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the complete bacterial SRP Alu domain.
Nucleic Acids Res., 42, 2014
6QR4
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Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
Descriptor: 5-azanyl-3-[1-[[(2~{R})-1-methylpiperidin-2-yl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile, tRNA (guanine-N(1)-)-methyltransferase
Authors:Thomas, S.E, Whitehouse, A.J, Coyne, A.G, Abell, C, Mendes, V, Blundell, T.L.
Deposit date:2019-02-19
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches.
J.Med.Chem., 62, 2019
8CLM
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BU of 8clm by Molmil
1.80 A crystal structure of RNA/2'-O-methyl-RNA heteroduplex
Descriptor: POTASSIUM ION, RNA (5'-R(*(UZL)*(OMU)P*(A2M)P*(OMG)P*(OMG)P*(A2M)P*(OMG)P*(A2M)P*(OMC)P*)-3'), RNA (5'-R(*G*UP*CP*UP*CP*CP*UP*AP*GP*)-3'), ...
Authors:Dolot, R.M, Maciaszek, A, Nawrot, B.C.
Deposit date:2023-02-16
Release date:2023-03-01
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of RNA/2'-O-methyl-RNA heteroduplex
To Be Published
6QR0
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BU of 6qr0 by Molmil
Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
Descriptor: 5-azanyl-3-[1-(pyridin-4-ylmethyl)indol-6-yl]-1~{H}-pyrazole-4-carbonitrile, SULFATE ION, tRNA (guanine-N(1)-)-methyltransferase
Authors:Thomas, S.E, Whitehouse, A.J, Coyne, A.G, Abell, C, Mendes, V, Blundell, T.L.
Deposit date:2019-02-19
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches.
J.Med.Chem., 62, 2019
7S38
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BU of 7s38 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) forming a 3-base-pair R-loop
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
2MBY
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BU of 2mby by Molmil
NMR Structure of Rrp7 C-terminal Domain
Descriptor: Ribosomal RNA-processing protein 7
Authors:Lin, J, Feng, Y, Ye, K.
Deposit date:2013-08-08
Release date:2013-09-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An RNA-Binding Complex Involved in Ribosome Biogenesis Contains a Protein with Homology to tRNA CCA-Adding Enzyme.
Plos Biol., 11, 2013
4UQZ
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BU of 4uqz by Molmil
Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes
Descriptor: ACETATE ION, HSIB1, HSIE1
Authors:Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A.
Deposit date:2014-06-25
Release date:2014-10-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
RNA, 20, 2014
6OZH
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BU of 6ozh by Molmil
Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine
Descriptor: CALCIUM ION, DNA/RNA (5'-D(P*CP*GP*GP*TP*AP*AP*CP*CP*GP*I)-R(P*A)-D(P*TP*AP*TP*GP*CP*AP*GP*CP*AP*TP*TP*TP*C)-3'), endonuclease V isoform X2
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.026 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6YBV
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BU of 6ybv by Molmil
Structure of a human 48S translational initiation complex - eIF2-TC
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6YMV
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BU of 6ymv by Molmil
Cryo-EM structure of yeast mitochondrial RNA polymerase partially-melted transcription initiation complex (PmIC)
Descriptor: DNA (33-MER) NON-TEMPLATE, DNA (33-MER) template, DNA-directed RNA polymerase, ...
Authors:Das, K, Patel, S.S.
Deposit date:2020-04-10
Release date:2020-12-02
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase.
Mol.Cell, 81, 2021
6OZI
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BU of 6ozi by Molmil
Crystal structure of Ciona intestinalis (Ci) Endonuclease V (D234N) in complex with a 23mer DNA containing an inosine followed by a ribo-adenosine
Descriptor: DNA/RNA (23-MER), POTASSIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Samara, N.L, Yang, W.
Deposit date:2019-05-15
Release date:2019-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
7W9S
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BU of 7w9s by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ...
Authors:Wang, M, Gong, P.
Deposit date:2021-12-10
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis.
Nucleic Acids Res., 50, 2022
6Y83
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BU of 6y83 by Molmil
Capsid structure of Leishmania RNA virus 1
Descriptor: Capsid protein
Authors:Prochazkova, M, Fuzik, T, Grybtchuk, D, Falginella, F, Podesvova, L, Yurchenko, V, Vacha, R, Plevka, P.
Deposit date:2020-03-03
Release date:2020-11-11
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Capsid Structure of Leishmania RNA Virus 1.
J.Virol., 95, 2021
6VJS
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BU of 6vjs by Molmil
Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex
Descriptor: 3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Murakami, K.S, Molodtsov, V.
Deposit date:2020-01-17
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.02 Å)
Cite:Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice.
Acs Infect Dis., 6, 2020
6YMW
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BU of 6ymw by Molmil
Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex
Descriptor: Chains: N, Chains: T, DNA-directed RNA polymerase, ...
Authors:Das, K, Patel, S.S.
Deposit date:2020-04-10
Release date:2020-12-09
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase.
Mol.Cell, 81, 2021
1PKP
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BU of 1pkp by Molmil
THE STRUCTURE OF RIBOSOMAL PROTEIN S5 REVEALS SITES OF INTERACTION WITH 16S RRNA
Descriptor: RIBOSOMAL PROTEIN S5
Authors:Ramakrishnan, V, White, S.W.
Deposit date:1993-08-30
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA.
Nature, 358, 1992
7UZY
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BU of 7uzy by Molmil
Staphylococcus epidermidis RP62A CRISPR effector complex with non-self target RNA 2
Descriptor: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ...
Authors:Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
Deposit date:2022-05-09
Release date:2022-07-06
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
8V38
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BU of 8v38 by Molmil
Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1)
Descriptor: SID1 transmembrane family member 1,RNA-directed RNA polymerase L
Authors:Navratna, V, Kumar, A, Rana, J.K, Mosalaganti, S.
Deposit date:2023-11-27
Release date:2024-06-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain.
Biorxiv, 2024
3RRM
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BU of 3rrm by Molmil
S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K.
Deposit date:2011-04-29
Release date:2011-05-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
5GJB
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BU of 5gjb by Molmil
Zika virus NS3 helicase in complex with ssRNA
Descriptor: NS3 helicase, RNA (5'-R(*AP*GP*AP*UP*CP*AP*A)-3')
Authors:Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H.
Deposit date:2016-06-28
Release date:2016-07-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural basis of Zika virus helicase in recognizing its substrates
Protein Cell, 7, 2016
3BK1
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BU of 3bk1 by Molmil
Crystal Structure Analysis of RNase J
Descriptor: GLYCEROL, Metal dependent hydrolase, SULFATE ION, ...
Authors:de la Sierra-Gallay, I.L, Zig, L, Putzer, H.
Deposit date:2007-12-05
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural insights into the dual activity of RNase J
Nat.Struct.Mol.Biol., 15, 2008

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