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4LIS
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BU of 4lis by Molmil
Crystal Structure of UDP-galactose-4-epimerase from Aspergillus nidulans
Descriptor: GLYCEROL, IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Dalrymple, S.A, Ko, J, Sheoran, I, Kaminskyj, S.G.W, Sanders, D.A.R.
Deposit date:2013-07-03
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase.
Plos One, 8, 2013
4K90
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BU of 4k90 by Molmil
Extracellular metalloproteinase from Aspergillus
Descriptor: BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ...
Authors:Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I.
Deposit date:2013-04-19
Release date:2013-10-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.
Acta Crystallogr.,Sect.D, 69, 2013
4IUG
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BU of 4iug by Molmil
Crystal structure of beta-galactosidase from Aspergillus oryzae in complex with galactose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-6-O-phosphono-beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose, ...
Authors:Maksimainen, M, Rouvinen, J.
Deposit date:2013-01-21
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of acidic beta-galactosidase from Aspergillus oryzae.
Int.J.Biol.Macromol., 60C, 2013
4IDX
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BU of 4idx by Molmil
hexameric crystal structure of Schmallenberg virus nucleoprotein
Descriptor: Nucleocapsid protein
Authors:Dong, H, Dong, C.
Deposit date:2012-12-13
Release date:2013-04-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structure of Schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism of genome encapsidation
J.Virol., 87, 2013
4IS8
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BU of 4is8 by Molmil
Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors
Descriptor: Nuclear receptor subfamily 5 group A member 2
Authors:Musille, P.M, Pathak, M.C, Ortlund, E.A.
Deposit date:2013-01-16
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors.
J.Biol.Chem., 288, 2013
3PRG
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BU of 3prg by Molmil
LIGAND BINDING DOMAIN OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
Descriptor: PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Authors:Uppenberg, J, Svensson, C, Jaki, M, Bertilsson, G, Jendeberg, L, Berkenstam, A.
Deposit date:1998-08-24
Release date:1999-08-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma.
J.Biol.Chem., 273, 1998
3RWK
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BU of 3rwk by Molmil
First crystal structure of an endo-inulinase, from Aspergillus ficuum: structural analysis and comparison with other GH32 enzymes.
Descriptor: ACETATE ION, Inulinase, SODIUM ION, ...
Authors:Michaux, C, Pouyez, J, Roussel, G, Mayard, A, Vandamme, A.M, Housen, I, Wouters, J.
Deposit date:2011-05-09
Release date:2012-07-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity.
Biochimie, 94, 2012
7JJO
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BU of 7jjo by Molmil
Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor
Descriptor: Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y.
Deposit date:2020-07-27
Release date:2020-09-02
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
3RJA
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BU of 3rja by Molmil
Crystal structure of carbohydrate oxidase from Microdochium nivale in complex with substrate analogue
Descriptor: (2R,3R,4R,5R)-4,5-dihydroxy-2-(hydroxymethyl)-6-oxopiperidin-3-yl beta-D-glucopyranoside, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Duskova, J, Skalova, T, Kolenko, P, Stepankova, A, Koval, T, Hasek, J, Ostergaard, L.H, Fuglsang, C.C, Dohnalek, J.
Deposit date:2011-04-15
Release date:2012-04-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and kinetic studies of carbohydrate oxidase from Microdochium nivale
To be Published
3SC7
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BU of 3sc7 by Molmil
First crystal structure of an endo-inulinase, from Aspergillus ficuum: structural analysis and comparison with other GH32 enzymes.
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Inulinase, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, ...
Authors:Housen, I, Pouyez, J, Roussel, G, Mayard, A, Vandamme, A.M, Wouters, J, Michaux, C.
Deposit date:2011-06-07
Release date:2012-06-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:First crystal structure of an endo-inulinase, INU2, from Aspergillus ficuum: Discovery of an extra-pocket in the catalytic domain responsible for its endo-activity.
Biochimie, 94, 2012
4HW4
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BU of 4hw4 by Molmil
Discovery of potent Mcl-1 inhibitors using fragment-based methods and structure-based design
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 BH3 peptide
Authors:Friberg, A, Zhao, B.
Deposit date:2012-11-07
Release date:2013-01-09
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.
J.Med.Chem., 56, 2013
3RJ8
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BU of 3rj8 by Molmil
Crystal structure of carbohydrate oxidase from Microdochium nivale
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carbohydrate oxidase, ...
Authors:Duskova, J, Skalova, T, Stepankova, A, Koval, T, Hasek, J, Ostergaard, L.H, Fuglsang, C.C, Kolenko, P, Dohnalek, J.
Deposit date:2011-04-15
Release date:2012-04-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure and kinetic studies of carbohydrate oxidase from Microdochium nivale
To be Published
3UBD
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BU of 3ubd by Molmil
Structure of N-terminal domain of RSK2 kinase in complex with flavonoid glycoside SL0101
Descriptor: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3
Authors:Utepbergenov, D, Derewenda, U, Derewenda, Z.S.
Deposit date:2011-10-24
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
4JK8
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BU of 4jk8 by Molmil
Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Mg ion
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
Deposit date:2013-03-09
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKF
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BU of 4jkf by Molmil
Open and closed forms of T1791P+R1865A human PRP8 RNase H-like domain with bound Mg ion
Descriptor: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
Deposit date:2013-03-09
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKE
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BU of 4jke by Molmil
Open and closed forms of T1789P human PRP8 RNase H-like domain with bound Mg ion
Descriptor: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
Deposit date:2013-03-09
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4JKA
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BU of 4jka by Molmil
Open and closed forms of R1865A human PRP8 RNase H-like domain with bound Co ion
Descriptor: CHLORIDE ION, COBALT (II) ION, Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
Deposit date:2013-03-09
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4LE2
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BU of 4le2 by Molmil
Crystal structure of the unphosphorylated receiver domain of DesR in the active state
Descriptor: PHOSPHATE ION, POTASSIUM ION, Transcriptional regulatory protein DesR
Authors:Trajtenberg, F, Larrieux, N, Buschiazzo, A.
Deposit date:2013-06-25
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
4LE0
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BU of 4le0 by Molmil
Crystal structure of the receiver domain of DesR in complex with beryllofluoride and magnesium
Descriptor: ACETATE ION, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ...
Authors:Trajtenberg, F, Larrieux, N, Buschiazzo, A.
Deposit date:2013-06-25
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
4LE1
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BU of 4le1 by Molmil
Crystal structure of the receiver domain of DesR in the inactive state
Descriptor: ACETATE ION, GLYCEROL, SULFATE ION, ...
Authors:Trajtenberg, F, Larrieux, N, Buschiazzo, A.
Deposit date:2013-06-25
Release date:2014-07-16
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
4JKG
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BU of 4jkg by Molmil
Open and closed forms of mixed T1789P+R1865A and R1865A human PRP8 RNase H-like domain with bound Mg ion
Descriptor: MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8
Authors:Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
Deposit date:2013-03-09
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013
4LDZ
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BU of 4ldz by Molmil
Crystal structure of the full-length response regulator DesR in the active state
Descriptor: BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Trajtenberg, F, Larrieux, N, Buschiazzo, A.
Deposit date:2013-06-25
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
7KP5
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BU of 7kp5 by Molmil
Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin
Descriptor: Beta-lactoglobulin, DODECYL SULFATE
Authors:Rodriguez-Hernandez, A, Rodriguez-Romero, A.
Deposit date:2020-11-10
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Energetic and structural effects of the Tanford transition on ligand recognition of bovine beta-lactoglobulin.
Arch.Biochem.Biophys., 699, 2021
7KOT
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BU of 7kot by Molmil
Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin
Descriptor: Beta-lactoglobulin, DODECYL SULFATE
Authors:Rodriguez-Hernandez, A, Rodriguez-Romero, A.
Deposit date:2020-11-09
Release date:2021-01-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Energetic and structural effects of the Tanford transition on ligand recognition of bovine beta-lactoglobulin.
Arch.Biochem.Biophys., 699, 2021
4JKB
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BU of 4jkb by Molmil
Open and closed forms of V1788D human PRP8 RNase H-like domain with bound Mg ion
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M.
Deposit date:2013-03-09
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Nat.Struct.Mol.Biol., 20, 2013

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