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6N6M
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BU of 6n6m by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R189A
Descriptor: ATP synthase SpaL/MxiB, SULFATE ION
Authors:Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
Deposit date:2018-11-26
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.788 Å)
Cite:Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N70
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BU of 6n70 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R191A
Descriptor: ATP synthase SpaL/MxiB
Authors:Morales, Y, Olsen, K.J, Johnson, S.J, Demler, H.J, Dickenson, N.E.
Deposit date:2018-11-27
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.738 Å)
Cite:Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6O0H
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BU of 6o0h by Molmil
Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate
Authors:Wei, J, Tong, L.
Deposit date:2019-02-16
Release date:2019-04-17
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:An allosteric mechanism for potent inhibition of human ATP-citrate lyase.
Nature, 568, 2019
6UV5
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BU of 6uv5 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-11-01
Release date:2019-12-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
1OBG
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BU of 1obg by Molmil
SAICAR-synthase complexed with ATP
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, PHOSPHORIBOSYLAMIDOIMIDAZOLE- SUCCINOCARBOXAMIDE SYNTHASE, ...
Authors:Antonyuk, S.V, Grebenko, A.I, Levdikov, V.M, Urusova, D.V, Melik-Adamyan, W.R, Lamzin, V.S, Wilson, K.
Deposit date:2003-01-30
Release date:2003-03-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-Ray Structure of Saicar-Synthase Complexed with ATP
Kristallografiya, 46, 2001
6HXM
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Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
Descriptor: ATP-citrate synthase, CITRATE ANION, COENZYME A
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6NZY
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BU of 6nzy by Molmil
Structural Determination of the Carboxy-terminal portion of ATP-citrate lyase
Descriptor: ACETYL COENZYME *A, ATP-citrate lyase alpha-subunit, GLYCEROL, ...
Authors:Nguyen, V.H, Fraser, M.E.
Deposit date:2019-02-14
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of the active site residues in ATP-citrate lyase's carboxy-terminal portion.
Protein Sci., 28, 2019
3DZE
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BU of 3dze by Molmil
Crystal structure of bovine coupling Factor B bound with cadmium
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ...
Authors:Lee, J.K, Stroud, R.M, Belogrudov, G.I.
Deposit date:2008-07-29
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3E3Z
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BU of 3e3z by Molmil
Crystal structure of bovine coupling Factor B bound with phenylarsine oxide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ...
Authors:Stroud, R.M, Lee, J.K, Belogrudov, G.I.
Deposit date:2008-08-08
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3E4G
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BU of 3e4g by Molmil
Crystal structure of bovine coupling Factor B, G28E mutant
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ...
Authors:Stroud, R.M, Lee, J.K, Belogrudov, G.I.
Deposit date:2008-08-11
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6HXN
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BU of 6hxn by Molmil
Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P3121)
Descriptor: ATP-citrate lyase alpha-subunit, COENZYME A, SULFATE ION
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
2CNV
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BU of 2cnv by Molmil
SAICAR-synthase from Saccharomyces cerevisiae complexed SAICAR
Descriptor: ASPARTIC ACID, N-{[5-AMINO-1-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-1H-IMIDAZOL-4-YL]CARBONYL}-L-ASPARTIC ACID, PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE, ...
Authors:Urusova, D.V, Antonyuk, S.V, Grebenko, A.I, Levdikov, V.M, Barynin, V.V, Popov, A.N, Lamzin, V.S, Melik-Adamyan, V.R.
Deposit date:2006-05-24
Release date:2006-06-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Diffraction Study of the Complex of the Enzyme Saicar Synthase with the Reaction Product
Crystallogr.Rep.(Transl. Kristallografiya), 51, 2006
5TEQ
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BU of 5teq by Molmil
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
Descriptor: ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDE
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BU of 5tde by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
Descriptor: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
Authors:Hu, J, Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
2P4X
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BU of 2p4x by Molmil
Crystal Structure of Atp12 from Paracoccus Denitrificans
Descriptor: ATP12 ATPase
Authors:Ludlam, A.V, Brunzelle, J.S, Gatti, D.L, Ackerman, S.H.
Deposit date:2007-03-13
Release date:2008-03-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Atp12 from Paracoccus Denitrificans
To be Published
1A48
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BU of 1a48 by Molmil
SAICAR SYNTHASE
Descriptor: PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE, SULFATE ION
Authors:Levdikov, V.M, Melik-Adamyan, W.R, Lamzin, V.S, Wilson, K.S.
Deposit date:1998-02-12
Release date:1999-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis.
Structure, 6, 1998
6L6Z
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BU of 6l6z by Molmil
Cryo-EM structure of the Drosophila CTP synthase substrate-bound filament
Descriptor: CTP synthase
Authors:Ji-Long, L, Xian, Z, Chen-Jun, G.
Deposit date:2019-10-30
Release date:2020-03-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.09 Å)
Cite:Drosophila CTP synthase can form distinct substrate- and product-bound filaments.
J Genet Genomics, 46, 2019
6LFG
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BU of 6lfg by Molmil
Cryo-EM structure of the Drosophila CTP synthase product-bound filament
Descriptor: CTP synthase
Authors:Ji-long, L, Xian, Z, Chen-Jun, G.
Deposit date:2019-12-02
Release date:2020-03-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.58 Å)
Cite:Drosophila CTP synthase can form distinct substrate- and product-bound filaments.
J Genet Genomics, 46, 2019
5U05
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BU of 5u05 by Molmil
Cryo-EM structure of the E. coli CTP synthase tetramer
Descriptor: CTP synthase
Authors:Lynch, E.M, Hicks, D.R, Kollman, J.M.
Deposit date:2016-11-22
Release date:2017-04-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Human CTP synthase filament structure reveals the active enzyme conformation.
Nat. Struct. Mol. Biol., 24, 2017
3ZDI
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BU of 3zdi by Molmil
Glycogen Synthase Kinase 3 Beta complexed with Axin Peptide and Inhibitor 7d
Descriptor: 3,6-Diamino-4-(2-chlorophenyl)thieno[2,3-b]pyridine-2,5-dicarbonitrile, AXIN-1, GLYCOGEN SYNTHASE KINASE-3 BETA, ...
Authors:Oberholzer, A.E, Pearl, L.H.
Deposit date:2012-11-27
Release date:2012-12-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:3,6-Diamino-4-(2-Halophenyl)-2-Benzoylthieno(2,3-B) Pyridine-5-Carbonitriles are Selective Inhibitors of Plasmodium Falciparum Glycogen Synthase Kinase-3 (Pfgsk-3)
J.Med.Chem., 56, 2013
2IWZ
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BU of 2iwz by Molmil
Human mitochondrial beta-ketoacyl ACP synthase complexed with hexanoic acid
Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, AMMONIUM ION, HEXANOIC ACID
Authors:Christensen, C.E, Kragelund, B.B, von Wettstein-Knowles, P, Henriksen, A.
Deposit date:2006-07-05
Release date:2007-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase.
Protein Sci., 16, 2007
5KPM
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BU of 5kpm by Molmil
Glycogen Synthase Kinase 3 beta Complexed with BRD3731
Descriptor: (4~{S})-3-(2,2-dimethylpropyl)-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta
Authors:Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K.
Deposit date:2016-07-04
Release date:2018-03-14
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.
Sci Transl Med, 10, 2018
5KPL
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BU of 5kpl by Molmil
Glycogen Synthase Kinase 3 beta Complexed with BRD0705
Descriptor: (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta
Authors:Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K.
Deposit date:2016-07-04
Release date:2018-03-14
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.
Sci Transl Med, 10, 2018
4UTQ
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BU of 4utq by Molmil
A structural model of the active ribosome-bound membrane protein insertase YidC
Descriptor: ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC
Authors:Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R.
Deposit date:2014-07-22
Release date:2014-07-30
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8 Å)
Cite:A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc.
Elife, 3, 2014
6NJP
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BU of 6njp by Molmil
Structure of the assembled ATPase EscN in complex with its central stalk EscO from the enteropathogenic E. coli (EPEC) type III secretion system
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, EscO, ...
Authors:Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J.
Deposit date:2019-01-03
Release date:2019-02-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019

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