PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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4XAX	Crystal structure of Thermus thermophilus CarD in complex with the Thermus aquaticus RNA polymerase beta1 domain Descriptor: 1,2-ETHANEDIOL, CarD, DNA-directed RNA polymerase subunit beta domain 1 Authors: Chen, J, Bae, B, Campbell, E.A, Darst, S.A. Deposit date: 2014-12-15 Release date: 2015-09-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.404 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
6UU4	E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.305 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTW	E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal) Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.854 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UUC	E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.096 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU5	E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked with GTP, UTP, CTP, and dinucleotide GpA for 30 minutes) Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (5.403 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
8B0J	CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis Descriptor: GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E Authors: Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. Deposit date: 2022-09-07 Release date: 2022-10-05 Last modified: 2023-01-25 Method: ELECTRON MICROSCOPY (3.99 Å) Cite: Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis. Embo J., 42, 2023
7QY5	Crystal structure of the S.pombe Ars2-Red1 complex. Descriptor: NURS complex subunit pir2, RNA elimination defective protein Red1, ZINC ION Authors: Foucher, A.E, Kadlec, J. Deposit date: 2022-01-27 Release date: 2022-11-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex. Nat Commun, 13, 2022
6CO1	Structure of human TIRR in complex with 53BP1 Tudor domains Descriptor: TP53-binding protein 1, Tudor-interacting repair regulator protein Authors: Cui, G, Botuyan, M.V, Mer, G. Deposit date: 2018-03-10 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.179 Å) Cite: Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
7YR7	Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with three RsmA protein dimers Descriptor: RsmZ RNA (118-MER), Translational regulator CsrA Authors: Jia, X, Pan, Z, Yuan, Y, Luo, B, Luo, Y, Mukherjee, S, Jia, G, Liu, L, Ling, X, Yang, X, Wu, Y, Liu, T, Miao, Z, Wei, X, Bujnicki, J.M, Zhao, K, Su, Z. Deposit date: 2022-08-09 Release date: 2023-05-17 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence. Cell Res., 33, 2023
7YR6	Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with two RsmA protein dimers Descriptor: RsmZ RNA, Translational regulator CsrA Authors: Jia, X, Pan, Z, Yuan, Y, Luo, B, Luo, Y, Mukherjee, S, Jia, G, Ling, X, Yang, X, Wu, Y, Liu, T, Wei, X, Bujnick, J.M, Zhao, K, Su, Z. Deposit date: 2022-08-09 Release date: 2023-05-17 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence. Cell Res., 33, 2023
8GHU	Methyltransferase RmtC bound to the 30S ribosomal subunit Descriptor: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ... Authors: Srinivas, P, Conn, G.L, Dunham, C.M. Deposit date: 2023-03-12 Release date: 2023-04-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3 Å) Cite: 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Biorxiv, 2023
2HZC	Crystal structure of the N-terminal RRM of the U2AF large subunit Descriptor: HEXAETHYLENE GLYCOL, Splicing factor U2AF 65 kDa subunit, ZINC ION Authors: Thickman, K.R, Sickmier, E.A, Kielkopf, C.L. Deposit date: 2006-08-08 Release date: 2006-08-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Alternative Conformations at the RNA-binding Surface of the N-terminal U2AF(65) RNA Recognition Motif. J.Mol.Biol., 366, 2007
6IEW	The crystal structure of the dNxf2 UBA domain in complex with Panoramix Descriptor: Fusion protein of Nuclear RNA export factor 2 and Protein panoramix, GLYCEROL Authors: Huang, Y, Cheng, S. Deposit date: 2018-09-17 Release date: 2019-08-21 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation. Nat.Cell Biol., 21, 2019
4BY7	elongating RNA Polymerase II-Bye1 TLD complex Descriptor: , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. Deposit date: 2013-07-18 Release date: 2013-09-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
6M7J	Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin Descriptor: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. Deposit date: 2018-08-20 Release date: 2018-11-21 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
5LR4	RNA duplex has central consecutive GA pairs flanked by G-U basepairs with a methyl group on the adenine N6 Descriptor: RNA (5'-R(*GP*(CBV)P*CP*GP*GP*(6MZ)P*UP*GP*GP*C)-3'), SODIUM ION Authors: Huang, L, Lilley, D.M.J. Deposit date: 2016-08-18 Release date: 2017-06-21 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Control of box C/D snoRNP assembly by N(6)-methylation of adenine. EMBO Rep., 18, 2017
6H0R	X-ray structure of SRS2 fragment of Rgs4 3' UTR Descriptor: BARIUM ION, MAGNESIUM ION, SRS2 fragment of Rgs4 3' UTR, ... Authors: Heber, S, Janowski, R, Niessing, D. Deposit date: 2018-07-10 Release date: 2019-04-17 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains. Nat Commun, 10, 2019
2IX1	RNase II D209N mutant Descriptor: 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP *AP*AP*A)-3', EXORIBONUCLEASE 2, MAGNESIUM ION Authors: Frazao, C, McVey, C.E, Amblar, M, Barbas, A, Vonrhein, C, Arraiano, C.M, Carrondo, M.A. Deposit date: 2006-07-05 Release date: 2006-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Unravelling the Dynamics of RNA Degradation by Ribonuclease II and its RNA-Bound Complex Nature, 443, 2006
5SZD	Crystal structure of Aquifex aeolicus Hfq at 1.5A Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... Authors: Stanek, K, Patterson, J, Randolph, P.S, Mura, C. Deposit date: 2016-08-13 Release date: 2017-04-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.494 Å) Cite: Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode. Acta Crystallogr D Struct Biol, 73, 2017
5LR3	RNA duplex has central consecutive GA pairs flanked by G-U basepairs Descriptor: RNA (5'-R(*GP*(CBV)P*CP*GP*GP*AP*UP*GP*GP*C)-3'), SULFATE ION Authors: Huang, L, Lilley, D.M.J. Deposit date: 2016-08-18 Release date: 2017-06-21 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Control of box C/D snoRNP assembly by N(6)-methylation of adenine. EMBO Rep., 18, 2017
5LQO	RNA duplex has central consecutive GA pairs flanked by G-C basepairs Descriptor: RNA (5'-R(*GP*(CBV)P*CP*GP*GP*AP*CP*GP*GP*C)-3') Authors: Huang, L, Lilley, D.M.J. Deposit date: 2016-08-17 Release date: 2017-06-21 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Control of box C/D snoRNP assembly by N(6)-methylation of adenine. EMBO Rep., 18, 2017
4BXX	Arrested RNA polymerase II-Bye1 complex Descriptor: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ... Authors: Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. Deposit date: 2013-07-16 Release date: 2013-09-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.28 Å) Cite: Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
4YCO	E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe Descriptor: FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, MANGANESE (II) ION, ... Authors: Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. Deposit date: 2015-02-20 Release date: 2015-04-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
3C4B	Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer Descriptor: Endoribonuclease Dicer Authors: Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. Deposit date: 2008-01-29 Release date: 2008-02-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
3C4T	Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer Descriptor: CADMIUM ION, Endoribonuclease Dicer Authors: Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. Deposit date: 2008-01-30 Release date: 2008-02-19 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008

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