4CZ4
 
 | | HP24stab derived from the villin headpiece subdomain | | Descriptor: | VILLIN-1 | | Authors: | Hocking, H, Haese, F, Madl, T, Zacharias, M, Rief, M, Zoldak, G. | | Deposit date: | 2014-04-16 | | Release date: | 2015-02-18 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A Compact Native 24-Residue Supersecondary Structure Derived from the Villin Headpiece Subdomain.
Biophys.J., 108, 2015
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4CNU
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4CNT
 | | CRYSTAL STRUCTURE OF WT HUMAN CRMP-4 | | Descriptor: | 1,2-ETHANEDIOL, DIHYDROPYRIMIDINASE-LIKE 3, SODIUM ION | | Authors: | Ponnusamy, R, Lohkamp, B. | | Deposit date: | 2014-01-24 | | Release date: | 2014-06-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation Disorder
Acta Crystallogr.,Sect.D, 70, 2014
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5EPZ
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5EQO
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5EM1
 | | Crystal structure of ragweed allergen Amb a 8 | | Descriptor: | BENZOIC ACID, CHLORIDE ION, Profilin | | Authors: | Offermann, L.R, He, J.Z, Perdue, M.L, Chruszcz, M. | | Deposit date: | 2015-11-05 | | Release date: | 2016-06-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
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5EOP
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5EM0
 | | Crystal structure of mugwort allergen Art v 4 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Pollen allergen Art v 4.01, SODIUM ION | | Authors: | Offermann, L.R, Perdue, M.L, Chruszcz, M. | | Deposit date: | 2015-11-05 | | Release date: | 2016-06-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
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8ILR
 | | Cryo-EM structure of PI3Kalpha in complex with compound 16 | | Descriptor: | N-[(2S)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | Authors: | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | | Deposit date: | 2023-03-04 | | Release date: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Proc.Natl.Acad.Sci.USA, 120, 2023
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2W2X
 | | Complex of Rac2 and PLCg2 spPH Domain | | Descriptor: | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | Deposit date: | 2008-11-04 | | Release date: | 2009-05-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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1K58
 | | Crystal Structure of Human Angiogenin Variant D116H | | Descriptor: | Angiogenin | | Authors: | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | Deposit date: | 2001-10-10 | | Release date: | 2002-03-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K5B
 | | Crystal Structure of Human Angiogenin Variant des(121-123) | | Descriptor: | Angiogenin, CITRIC ACID | | Authors: | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | Deposit date: | 2001-10-10 | | Release date: | 2002-03-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K59
 | | Crystal Structure of Human Angiogenin Variant Q117G | | Descriptor: | CITRIC ACID, angiogenin | | Authors: | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | Deposit date: | 2001-10-10 | | Release date: | 2002-03-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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1K5A
 | | Crystal structure of human angiogenin double variant I119A/F120A | | Descriptor: | Angiogenin | | Authors: | Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. | | Deposit date: | 2001-10-10 | | Release date: | 2002-03-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
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3EDU
 | | Crystal structure of the ankyrin-binding domain of human erythroid spectrin | | Descriptor: | Spectrin beta chain, erythrocyte | | Authors: | Simonovic, M, Stabach, P, Simonovic, I, Steitz, T.A, Morrow, J.S. | | Deposit date: | 2008-09-03 | | Release date: | 2009-02-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The structure of the ankyrin-binding site of {beta}-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
Blood, 113, 2009
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3N5C
 | | Crystal Structure of Arf6DELTA13 complexed with GDP | | Descriptor: | ADP-ribosylation factor 6, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Aizel, K, Biou, V, Cherfils, J. | | Deposit date: | 2010-05-25 | | Release date: | 2010-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6.
J.Mol.Biol., 402, 2010
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3NKJ
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9BDP
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5O33
 | | A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1 | | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Kalirin, ... | | Authors: | Gray, J, Krojer, T, Talon, R, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P, von Delft, F. | | Deposit date: | 2017-05-23 | | Release date: | 2017-05-31 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1
To Be Published
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9EM1
 | | Human pyridoxal phosphatase in complex with 7,8-dihydroxyflavone and phosphate | | Descriptor: | 7,8-bis(oxidanyl)-2-phenyl-chromen-4-one, Chronophin, GLYCEROL, ... | | Authors: | Brenner, M, Gohla, A, Schindelin, H. | | Deposit date: | 2024-03-07 | | Release date: | 2024-06-12 | | Last modified: | 2024-06-26 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | 7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase.
Elife, 13, 2024
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7O0B
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6Z47
 | | Smooth muscle myosin shutdown state heads region | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin heavy chain 11, ... | | Authors: | Scarff, C.A, Carrington, G, Casas Mao, D, Chalovich, J.M, Knight, P.J, Ranson, N.A, Peckham, M. | | Deposit date: | 2020-05-22 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (6.3 Å) | | Cite: | Structure of the shutdown state of myosin-2.
Nature, 588, 2020
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6OQQ
 | | Legionella pneumophila SidJ/Saccharomyces cerevisiae calmodulin complex | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | | Authors: | Tomchick, D.R, Tagliabracci, V.S, Black, M, Osinski, A. | | Deposit date: | 2019-04-28 | | Release date: | 2019-05-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases.
Science, 364, 2019
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6CU8
 | | Alpha Synuclein fibril formed by full length protein - Twister Polymorph | | Descriptor: | Alpha-synuclein | | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | | Deposit date: | 2018-03-23 | | Release date: | 2018-09-12 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
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4V8R
 | | The crystal structures of the eukaryotic chaperonin CCT reveal its functional partitioning | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Kalisman, N, Schroder, G.F, Levitt, M. | | Deposit date: | 2012-03-28 | | Release date: | 2014-07-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | The Crystal Structures of the Eukaryotic Chaperonin Cct Reveal its Functional Partitioning
Structure, 21, 2013
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