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1GX6
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Hepatitis C Virus RNA polymerase in complex with UTP and manganese
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE, URIDINE 5'-TRIPHOSPHATE
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2002-03-27
Release date:2002-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
3JB6
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BU of 3jb6 by Molmil
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ...
Authors:Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H.
Deposit date:2015-08-02
Release date:2015-10-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
3JB7
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BU of 3jb7 by Molmil
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Descriptor: CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H.
Deposit date:2015-08-03
Release date:2015-10-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
3EF1
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BU of 3ef1 by Molmil
The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
Descriptor: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase
Authors:Ghosh, A, Lima, C.D.
Deposit date:2008-09-07
Release date:2008-12-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.
Mol.Cell, 32, 2008
3EF0
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BU of 3ef0 by Molmil
The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
Descriptor: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAFLUOROALUMINATE ION
Authors:Ghosh, A, Lima, C.D.
Deposit date:2008-09-07
Release date:2008-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.
Mol.Cell, 32, 2008
2HAI
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BU of 2hai by Molmil
Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.
Descriptor: (6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE, HEPATITIS C VIRUS NS5B RNA POLYMERASE
Authors:Li, H, Love, R.L.
Deposit date:2006-06-12
Release date:2006-09-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
4BOC
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BU of 4boc by Molmil
Structure of mitochondrial RNA polymerase elongation complex
Descriptor: 5'-D(*CP*AP*TP*GP*GP*GP*GP*TP*AP*AP*TP*TP*AP*TP *TP*TP*CP*GP*AP*CP*GP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*CP*GP*TP*GP*CP*GP*CP *GP*CP*CP*GP*CP*TP*AP*CP*CP*CP*CP*AP*TP*G)-3', 5'-R(*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP)-3', ...
Authors:Schwinghammer, K, Cheung, A, Morozov, Y, Agaronyan, K, Temiakov, D, Cramer, P.
Deposit date:2013-05-18
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Nat.Struct.Mol.Biol., 20, 2013
3CJ4
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BU of 3cj4 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Antonysamy, s.s.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1GX5
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Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2002-03-27
Release date:2002-04-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
3CJ5
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide, RNA-directed RNA polymerase
Authors:Hendle, j.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ0
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BU of 3cj0 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
Descriptor: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CIZ
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BU of 3ciz by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
Descriptor: 2-amino-5-bromobenzoic acid, RNA-directed RNA polymerase, ZINC ION
Authors:Hendle, j.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
2PO4
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BU of 2po4 by Molmil
X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase
Descriptor: Virion RNA polymerase
Authors:Murakami, K.S, Davydova, E.K, Rothman-Denes, L.B.
Deposit date:2007-04-25
Release date:2008-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase
Proc.Natl.Acad.Sci.USA, 15, 2008
2RF4
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BU of 2rf4 by Molmil
Crystal structure of the RNA Polymerase I subcomplex A14/43
Descriptor: DNA-directed RNA polymerase I subunit RPA4
Authors:Geiger, S.R, Kuhn, C.D, Cramer, P.
Deposit date:2007-09-28
Release date:2008-01-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Functional architecture of RNA polymerase I.
Cell(Cambridge,Mass.), 131, 2007
1QUV
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BU of 1quv by Molmil
CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS
Descriptor: PROTEIN (RNA-DIRECTED RNA POLYMERASE)
Authors:Ago, H, Miyano, M, Adachi, T, Habuka, N.
Deposit date:1999-07-04
Release date:1999-11-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
Structure Fold.Des., 7, 1999
2GHQ
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BU of 2ghq by Molmil
CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y, Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
2GHT
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BU of 2ght by Molmil
CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y, Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
3GFK
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BU of 3gfk by Molmil
Crystal structure of Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex
Descriptor: DNA-directed RNA polymerase subunit alpha, Regulatory protein spx
Authors:Lamour, V, Westblade, L.F, Campbell, E.A, Darst, S.A.
Deposit date:2009-02-27
Release date:2009-03-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the in vivo-assembled Bacillus subtilis Spx/RNA polymerase alpha subunit C-terminal domain complex
J.Struct.Biol., 168, 2009
3K4G
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BU of 3k4g by Molmil
Crystal structure of E. coli RNA polymerase alpha subunit C-terminal domain
Descriptor: DNA-directed RNA polymerase subunit alpha, SODIUM ION
Authors:Lara-Gonzalez, S, Birktoft, J, Lawson, C.L.
Deposit date:2009-10-05
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the Escherichia coli RNA polymerase alpha subunit C-terminal domain.
Acta Crystallogr.,Sect.D, 66, 2010
3N4M
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BU of 3n4m by Molmil
E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ...
Authors:Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L.
Deposit date:2010-05-21
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.987 Å)
Cite:The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element.
Biochemistry, 59, 2020
3IHQ
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BU of 3ihq by Molmil
Crystal Structure of Reduced C10S Spx in Complex with the Alpha C-terminal Domain of RNA Polymeras
Descriptor: DNA-directed RNA polymerase subunit alpha, IMIDAZOLE, Regulatory protein spx
Authors:Newberry, K.J, Brennan, R.G.
Deposit date:2009-07-30
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
Plos One, 5, 2010
2MAX
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BU of 2max by Molmil
NMR structure of the RNA polymerase alpha subunit C-terminal domain from Helicobacter pylori
Descriptor: DNA-directed RNA polymerase subunit alpha
Authors:Borin, B.N, Krezel, A.M.
Deposit date:2013-07-21
Release date:2014-03-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Helicobacter pylori RNA polymerase alpha-subunit C-terminal domain shows features unique to -proteobacteria and binds NikR/DNA complexes.
Protein Sci., 23, 2014
1GO3
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BU of 1go3 by Molmil
Structure of an archeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex
Descriptor: DNA-DIRECTED RNA POLYMERASE SUBUNIT E, DNA-DIRECTED RNA POLYMERASE SUBUNIT F
Authors:Todone, F, Brick, P, Werner, F, Weinzierl, R.O.J, Onesti, S.
Deposit date:2001-10-17
Release date:2001-12-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an Archaeal Homolog of the Eukaryotic RNA Polymerase II Rpb4/Rpb7 Complex
Mol.Cell, 8, 2001

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