5WNX
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![BU of 5wnx by Molmil](/molmil-images/mine/5wnx) | DNA polymerase beta substrate complex with incoming 6-TdGTP | Descriptor: | 2-amino-9-{2-deoxy-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-1,9-dihydro-6H-purine-6-thione, CALCIUM ION, CHLORIDE ION, ... | Authors: | Schaich, M.A, Smith, M.R, Cloud, A.S, Holloran, S.M, Freudenthal, B.D. | Deposit date: | 2017-08-01 | Release date: | 2017-09-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. Chem. Res. Toxicol., 30, 2017
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5WTP
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![BU of 5wtp by Molmil](/molmil-images/mine/5wtp) | Crystal structure of the C-terminal domain of outer membrane protein A (OmpA) from Capnocytophaga gingivalis | Descriptor: | OmpA family protein, SULFATE ION | Authors: | Dai, S, Tan, K, Ye, S, Zhang, R. | Deposit date: | 2016-12-13 | Release date: | 2017-12-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of thrombospondin type 3 repeats in bacterial outer membrane protein A reveals its intra-repeat disulfide bond-dependent calcium-binding capability. Cell Calcium, 66, 2017
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5W7W
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![BU of 5w7w by Molmil](/molmil-images/mine/5w7w) | Crystal Structure of FHA domain of human APLF | Descriptor: | Aprataxin and PNK-like factor, FORMIC ACID, SODIUM ION | Authors: | Pedersen, L.C, Kim, K, London, R.E. | Deposit date: | 2017-06-21 | Release date: | 2018-05-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.348 Å) | Cite: | Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications. Nucleic Acids Res., 45, 2017
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5WN2
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5WO0
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![BU of 5wo0 by Molmil](/molmil-images/mine/5wo0) | DNA polymerase beta substrate complex with incoming 5-FodUTP | Descriptor: | 2'-deoxy-5-formyluridine 5'-(tetrahydrogen triphosphate), CALCIUM ION, CHLORIDE ION, ... | Authors: | Schaich, M.A, Smith, M.R, Cloud, A.S, Holloran, S.M, Freudenthal, B.D. | Deposit date: | 2017-08-01 | Release date: | 2017-09-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. Chem. Res. Toxicol., 30, 2017
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5WNZ
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![BU of 5wnz by Molmil](/molmil-images/mine/5wnz) | DNA polymerase beta substrate complex with incoming 5-FodCTP | Descriptor: | 2'-deoxy-5-formylcytidine 5'-(tetrahydrogen triphosphate), CALCIUM ION, CHLORIDE ION, ... | Authors: | Schaich, M.A, Smith, M.R, Cloud, A.S, Holloran, S.M, Freudenthal, B.D. | Deposit date: | 2017-08-01 | Release date: | 2017-09-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues. Chem. Res. Toxicol., 30, 2017
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4OI1
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![BU of 4oi1 by Molmil](/molmil-images/mine/4oi1) | Clp1 bound to ssRNA dinucleotide GC, ADP, AlF4-, and Mg2+(transition state, data set II) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | Deposit date: | 2014-01-18 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
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5WEY
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![BU of 5wey by Molmil](/molmil-images/mine/5wey) | Joint X-ray/neutron structure of Concanavalin A with alpha1-2 D-mannobiose | Descriptor: | CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ... | Authors: | Kovalevsky, A, Gerlits, O.O, Woods, R.J. | Deposit date: | 2017-07-11 | Release date: | 2017-09-13 | Last modified: | 2023-10-04 | Method: | NEUTRON DIFFRACTION (1.8 Å), X-RAY DIFFRACTION | Cite: | Mannobiose Binding Induces Changes in Hydrogen Bonding and Protonation States of Acidic Residues in Concanavalin A As Revealed by Neutron Crystallography. Biochemistry, 56, 2017
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5WP0
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![BU of 5wp0 by Molmil](/molmil-images/mine/5wp0) | Crystal structure of NAD synthetase NadE from Vibrio fischeri | Descriptor: | NH(3)-dependent NAD(+) synthetase | Authors: | Stogios, P.J, Evdokimova, E, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-08-03 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of NAD synthetase NadE from Vibrio fischeri To Be Published
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4OI2
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![BU of 4oi2 by Molmil](/molmil-images/mine/4oi2) | C. Elegans Clp1 and ADP and Mg2+ (turnover state) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | Deposit date: | 2014-01-18 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
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5WC9
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![BU of 5wc9 by Molmil](/molmil-images/mine/5wc9) | Human Pit-1 and 4xCATT DNA complex | Descriptor: | DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3'), Pituitary-specific positive transcription factor 1 | Authors: | Agarwal, S, Cho, T.Y. | Deposit date: | 2017-06-29 | Release date: | 2017-11-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter. Nucleic Acids Res., 46, 2018
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8HB9
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![BU of 8hb9 by Molmil](/molmil-images/mine/8hb9) | Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | Authors: | Guo, G, Wang, B, Liu, J, Liu, Q. | Deposit date: | 2022-10-27 | Release date: | 2023-05-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor. Eur.J.Med.Chem., 256, 2023
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8HIS
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![BU of 8his by Molmil](/molmil-images/mine/8his) | Crystal structure of DNA decamer containing GuNA[Me,tBu] | Descriptor: | CACODYLIC ACID, DNA (5'-D(*GP*CP*GP*TP*AP*(LR6)P*AP*CP*GP*C)-3') | Authors: | Aoyama, H, Obika, S, Yamaguchi, T. | Deposit date: | 2022-11-21 | Release date: | 2023-08-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Mechanism of the extremely high duplex-forming ability of oligonucleotides modified with N-tert-butylguanidine- or N-tert-butyl-N'- methylguanidine-bridged nucleic acids. Nucleic Acids Res., 51, 2023
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4Q4E
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![BU of 4q4e by Molmil](/molmil-images/mine/4q4e) | Crystal structure of E.coli aminopeptidase N in complex with actinonin | Descriptor: | ACTINONIN, Aminopeptidase N, GLYCEROL, ... | Authors: | Reddi, R, Ganji, R.J, Addlagatta, A. | Deposit date: | 2014-04-14 | Release date: | 2015-04-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Sci., 24, 2015
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8TCK
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8TCJ
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4QAX
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![BU of 4qax by Molmil](/molmil-images/mine/4qax) | Crystal structure of post-catalytic binary complex of Phosphoglycerate mutase from Staphylococcus aureus | Descriptor: | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, 2-PHOSPHOGLYCERIC ACID, MANGANESE (II) ION | Authors: | Roychowdhury, A, Kundu, A, Bose, M, Gujar, A, Das, A.K. | Deposit date: | 2014-05-06 | Release date: | 2015-05-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | STRUCTURAL AND FUNCCTIONAL ANALYSIS of PHOSPHOGLYCERATE MUTASE from STAPHYLOCOCCUS AUREUS To be Published
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4QTQ
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4OOB
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4OI0
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![BU of 4oi0 by Molmil](/molmil-images/mine/4oi0) | bound to ssRNA dinucleotide GC, ADP, AlF4-, and Mg2+(transition state, data set I) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | Deposit date: | 2014-01-18 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
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4ODX
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![BU of 4odx by Molmil](/molmil-images/mine/4odx) | |
4QXG
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![BU of 4qxg by Molmil](/molmil-images/mine/4qxg) | |
4QYF
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![BU of 4qyf by Molmil](/molmil-images/mine/4qyf) | CHK1 kinase domain in complex with aminopyrazine compound 13 | Descriptor: | 4-[3-amino-6-(3-hydroxyphenyl)pyrazin-2-yl]benzoic acid, Serine/threonine-protein kinase Chk1 | Authors: | Appleton, B, Wu, P. | Deposit date: | 2014-07-24 | Release date: | 2014-12-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
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4FNI
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![BU of 4fni by Molmil](/molmil-images/mine/4fni) | |
1CN4
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![BU of 1cn4 by Molmil](/molmil-images/mine/1cn4) | |