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8XUV
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BU of 8xuv by Molmil
Cryo-EM structure of tomato NRC2 filament
Descriptor: ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2
Authors:Sun, Y, Ma, S.C, Chai, J.J.
Deposit date:2024-01-14
Release date:2024-05-22
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Nature, 632, 2024
8XUQ
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BU of 8xuq by Molmil
Cryo-EM structure of tomato NRC2 tetramer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2
Authors:Sun, Y, Ma, S.C, Chai, J.J.
Deposit date:2024-01-14
Release date:2024-05-22
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Nature, 632, 2024
8XUO
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BU of 8xuo by Molmil
Cryo-EM structure of tomato NRC2 dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2
Authors:Sun, Y, Ma, S.C, Chai, J.J.
Deposit date:2024-01-13
Release date:2024-05-22
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR.
Nature, 632, 2024
7B1H
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BU of 7b1h by Molmil
Monoclinic P21 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-24
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
7B1F
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BU of 7b1f by Molmil
Orthorhombic P212121 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-24
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
7B1J
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BU of 7b1j by Molmil
Orthorhombic P21212 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-25
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
8ZKC
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BU of 8zkc by Molmil
iron-sulfur cluster transfer protein ApbC
Descriptor: GLYCEROL, Iron-sulfur cluster carrier protein, MAGNESIUM ION
Authors:Yang, J, Liu, L.
Deposit date:2024-05-16
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of the iron-sulfur cluster transfer protein ApbC from Escherichia coli.
Biochem.Biophys.Res.Commun., 722, 2024
6CKX
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BU of 6ckx by Molmil
Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide
Descriptor: Cyclin-K, Cyclin-dependent kinase 12, MAGNESIUM ION, ...
Authors:Klein, M.G.
Deposit date:2018-03-01
Release date:2018-08-29
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.
J. Med. Chem., 61, 2018
8A4O
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BU of 8a4o by Molmil
Crystal structure of the Ustilago hordei effector protein Uvi2
Descriptor: Effector protein Uvi2
Authors:Weiland, P, Bange, G, Altegoer, F.
Deposit date:2022-06-13
Release date:2023-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural and functional analysis of the cerato-platanin-like protein Cpl1 suggests diverging functions in smut fungi.
Mol Plant Pathol, 24, 2023
8A14
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BU of 8a14 by Molmil
Crystal structure of the cerato-platanin-like protein Cpl1 from Ustilago maydis
Descriptor: Cerato-platatanin-like protein 1
Authors:Weiland, P, Bange, G, Altegoer, F.
Deposit date:2022-05-31
Release date:2023-05-17
Last modified:2023-06-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional analysis of the cerato-platanin-like protein Cpl1 suggests diverging functions in smut fungi.
Mol Plant Pathol, 24, 2023
8YBK
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BU of 8ybk by Molmil
Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2024-02-14
Release date:2024-07-24
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
8Y37
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BU of 8y37 by Molmil
Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.
Descriptor: 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ...
Authors:Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
Deposit date:2024-01-28
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
8XSI
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BU of 8xsi by Molmil
SARS-CoV-2 RBD + IMCAS-364 (Local Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-364 H chain, IMCAS-364 L chain, ...
Authors:Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J.
Deposit date:2024-01-09
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
8YBJ
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BU of 8ybj by Molmil
Cryo-EM structure of human nucleosome core particle composed of the Widom 601 DNA sequence
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2024-02-14
Release date:2024-07-24
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
8Y0Y
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BU of 8y0y by Molmil
Cryo-EM structure of the 123-316 scDb/PT-RBD complex
Descriptor: 123-316 scDb, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Jia, G.W, Tong, Z, Tong, J.Y, Su, Z.M.
Deposit date:2024-01-23
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
8XSL
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BU of 8xsl by Molmil
SARS-CoV-2 spike + IMCAS-123
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-123 heavy chain, ...
Authors:Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J.
Deposit date:2024-01-09
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
8Y36
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BU of 8y36 by Molmil
cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190.
Descriptor: 23S ribosomal RNA, 5S ribosomal RNA, 7-[4-[3-[[(1~{S},2~{R},5~{R},6~{S},7~{S},8~{R},9~{R},11~{R},13~{R},14~{R})-8-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-4,12,16-tris(oxidanylidene)-3,17-dioxa-15-azabicyclo[12.3.0]heptadecan-6-yl]oxycarbonylamino]propoxy]but-1-ynyl]-1-methyl-4-oxidanylidene-quinoline-3-carboxylic acid, ...
Authors:Li, Y, Lu, G, Li, J, Pei, X, Lin, J.
Deposit date:2024-01-28
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Synthetic macrolides overcoming MLS B K-resistant pathogens.
Cell Discov, 10, 2024
8XSJ
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BU of 8xsj by Molmil
SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J.
Deposit date:2024-01-09
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
8XSE
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BU of 8xse by Molmil
SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-123 H chain, IMCAS-123 L chain, ...
Authors:Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J.
Deposit date:2024-01-09
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
8XSF
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BU of 8xsf by Molmil
SARS-CoV-2 RBD + IMCAS-364 + hACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, IMCAS-364 H chain, ...
Authors:Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J.
Deposit date:2024-01-09
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.16 Å)
Cite:Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
7VEI
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BU of 7vei by Molmil
Neutron structure of D2O-solvent lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, NICKEL (II) ION
Authors:Chatake, T, Tanaka, I, Kusaka, K, Fujiwara, S.
Deposit date:2021-09-08
Release date:2022-04-06
Last modified:2023-11-29
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Protonation states of hen egg-white lysozyme observed using D/H contrast neutron crystallography.
Acta Crystallogr D Struct Biol, 78, 2022
3D2A
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BU of 3d2a by Molmil
Structure of 1-17A4, a thermostable mutant of Bacillus subtilis lipase obtained through directed evolution
Descriptor: Lipase
Authors:Sankaranarayanan, R, Kamal, M.Z.
Deposit date:2008-05-08
Release date:2008-06-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Thermostable Bacillus subtilis lipases: in vitro evolution and structural insight
J.Mol.Biol., 381, 2008
3D2C
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BU of 3d2c by Molmil
Structure of 4D3, a thermostable mutant of Bacillus subtilis lipase obtained through directed evolution
Descriptor: Lipase
Authors:Sankaranarayanan, R, Kamal, M.Z.
Deposit date:2008-05-08
Release date:2008-06-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Thermostable Bacillus subtilis lipases: in vitro evolution and structural insight
J.Mol.Biol., 381, 2008
5IIA
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BU of 5iia by Molmil
Crystal structure of red abalone egg VERL repeat 3 in complex with sperm lysin at 1.7 A resolution (crystal form I)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Egg-lysin, Vitelline envelope sperm lysin receptor
Authors:Sadat Al-Hosseini, H, Raj, I, Nishimura, K, De Sanctis, D, Jovine, L.
Deposit date:2016-03-01
Release date:2017-06-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
7TE9
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BU of 7te9 by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1
Descriptor: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
Authors:Tajima, N, Furukawa, H.
Deposit date:2022-01-04
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022

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