5IIA

Crystal structure of red abalone egg VERL repeat 3 in complex with sperm lysin at 1.7 A resolution (crystal form I)

Summary for 5IIA

Entry DOI	10.2210/pdb5iia/pdb
Related	1LIS 1LYN 2LIS 2LYN 3D4C 3D4G 3EF7 3NK3 3NK4 5II4 5II5 5II7 5II8 5II9 5IIB 5IIC
Descriptor	Egg-lysin, Vitelline envelope sperm lysin receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	cell adhesion, fertilization, egg-sperm interaction, gamete recognition, sperm receptor, egg coat, vitelline envelope, zp domain, zp-n domain, sperm acrosome, egg coat penetration
Biological source	Haliotis rufescens (California red abalone) More
Cellular location	Cytoplasmic vesicle, secretory vesicle, acrosome lumen : P04552 Cell membrane ; Single-pass membrane protein : Q8WR62
Total number of polymer chains	8
Total formula weight	125188.65
Authors	Sadat Al-Hosseini, H.,Raj, I.,Nishimura, K.,De Sanctis, D.,Jovine, L. (deposition date: 2016-03-01, release date: 2017-06-14, Last modification date: 2024-01-10)
Primary citation	Raj, I.,Sadat Al Hosseini, H.,Dioguardi, E.,Nishimura, K.,Han, L.,Villa, A.,de Sanctis, D.,Jovine, L. Structural Basis of Egg Coat-Sperm Recognition at Fertilization. Cell, 169:1315-1326.e17, 2017 Cited by PubMed: 28622512 DOI: 10.1016/j.cell.2017.05.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation