2X46
| Crystal Structure of SeMet Arg r 1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALLERGEN ARG R 1 | Authors: | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | Deposit date: | 2010-01-28 | Release date: | 2011-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick To be Published
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7PWO
| Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ... | Authors: | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | Deposit date: | 2021-10-07 | Release date: | 2022-04-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. Nucleic Acids Res., 50, 2022
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7PWG
| Cryo-EM structure of large subunit of Giardia lamblia ribosome at 2.7 A resolution | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L18a, 60S ribosomal protein L27, ... | Authors: | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | Deposit date: | 2021-10-06 | Release date: | 2022-04-20 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. Nucleic Acids Res., 50, 2022
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4CA0
| Structural Basis for the microtubule binding of the human kinetochore Ska complex | Descriptor: | SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 | Authors: | Abad, M, Medina, B, Santamaria, A, Zou, J, Plasberg-Hill, C, Madhumalar, A, Jayachandran, U, Redli, P.M, Rappsilber, J, Nigg, E.A, Jeyaprakash, A.A. | Deposit date: | 2013-10-04 | Release date: | 2014-01-22 | Method: | X-RAY DIFFRACTION (2.259 Å) | Cite: | Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex. Nat.Commun., 5, 2014
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2HIG
| Crystal Structure of Phosphofructokinase apoenzyme from Trypanosoma brucei. | Descriptor: | 6-phospho-1-fructokinase, SODIUM ION | Authors: | Martinez-Oyanedel, J, McNae, I.W, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | Deposit date: | 2006-06-29 | Release date: | 2007-02-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The First Crystal Structure of Phosphofructokinase from a Eukaryote: Trypanosoma brucei. J.Mol.Biol., 366, 2007
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5VNF
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7PWF
| Cryo-EM structure of small subunit of Giardia lamblia ribosome at 2.9 A resolution | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | Authors: | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | Deposit date: | 2021-10-06 | Release date: | 2022-05-25 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. Nucleic Acids Res., 50, 2022
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3DTU
| Catalytic core subunits (I and II) of cytochrome c oxidase from Rhodobacter sphaeroides complexed with deoxycholic acid | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, CADMIUM ION, CALCIUM ION, ... | Authors: | Qin, L, Mills, D.A, Buhrow, L, Hiser, C, Ferguson-Miller, S. | Deposit date: | 2008-07-15 | Release date: | 2008-09-16 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A conserved steroid binding site in cytochrome C oxidase. Biochemistry, 47, 2008
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4E5A
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2CAG
| CATALASE COMPOUND II | Descriptor: | CATALASE COMPOUND II, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gouet, P, Jouve, H.M, Hajdu, J. | Deposit date: | 1996-06-12 | Release date: | 1996-12-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy. Nat.Struct.Biol., 3, 1996
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8QOH
| Crystal structure of the kinetoplastid kinetochore protein KKT14 C-terminal domain from Apiculatamorpha spiralis | Descriptor: | kinetochore protein KKT14 | Authors: | Carter, W, Ballmer, D, Ishii, M, Ludzia, P, Akiyoshi, B. | Deposit date: | 2023-09-28 | Release date: | 2024-01-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins. Open Biology, 14, 2024
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5N1V
| Crystal structure of the protein kinase CK2 catalytic subunit in complex with pyrazolo-pyrimidine macrocyclic ligand | Descriptor: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | Authors: | Robb, G, Ferguson, A, Hargreaves, D. | Deposit date: | 2017-02-06 | Release date: | 2017-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
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1X8I
| Crystal Structure of the Zinc Carbapenemase CphA in Complex with the Antibiotic Biapenem | Descriptor: | 5H-PYRAZOLO(1,2-A)(1,2,4)TRIAZOL-4-IUM, 6-((2-CARBOXY-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-EN-3-YL)THIO)-6,7-DIHYDRO-, HYDROXIDE, ... | Authors: | Garau, G, Dideberg, O. | Deposit date: | 2004-08-18 | Release date: | 2004-12-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Metallo-beta-lactamase Enzyme in Action: Crystal Structures of the Monozinc Carbapenemase CphA and its Complex with Biapenem J.Mol.Biol., 345, 2005
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5L6Q
| Refolded AL protein from cardiac amyloidosis | Descriptor: | CARBONATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Annamalai, K, Liberta, F, Vielberg, M.-T, Lilie, H, Guehrs, K.-H, Schierhorn, A, Koehler, R, Schmidt, A, Haupt, C, Hegenbart, O, Schoenland, S, Groll, M, Faendrich, M. | Deposit date: | 2016-05-31 | Release date: | 2017-05-31 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo. Angew. Chem. Int. Ed. Engl., 56, 2017
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2F6G
| BenM effector binding domain | Descriptor: | CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION | Authors: | Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C. | Deposit date: | 2005-11-29 | Release date: | 2006-10-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.908 Å) | Cite: | Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol., 367, 2007
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2F7B
| CatM effector binding domain | Descriptor: | CHLORIDE ION, HTH-type transcriptional regulator catM, SULFATE ION | Authors: | Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C. | Deposit date: | 2005-11-30 | Release date: | 2006-10-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol., 367, 2007
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5YVG
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8OOI
| Full composite cryo-EM map of p97/VCP in ADP.Pi state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Cheng, T.C, Sakata, E, Schuetz, A.K. | Deposit date: | 2023-04-05 | Release date: | 2024-01-31 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
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5N20
| Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand | Descriptor: | B-cell lymphoma 6 protein, ~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[(3~{R})-3-(dimethylamino)pyrrolidin-1-yl]phenyl]ethanamide | Authors: | Robb, G, Ferguson, A, Hargreaves, D. | Deposit date: | 2017-02-06 | Release date: | 2017-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
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2F6P
| BenM effector binding domain- SeMet derivative | Descriptor: | ACETATE ION, HTH-type transcriptional regulator benM, SODIUM ION, ... | Authors: | Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C. | Deposit date: | 2005-11-29 | Release date: | 2006-10-31 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol., 367, 2007
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7VQT
| Crystal structure of LSD1 in complex with compound 5 | Descriptor: | 3-[3,5-bis(fluoranyl)-2-[(2-fluoranylpyridin-4-yl)methoxy]phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Niwa, H, Koda, Y, Sato, S, Yamamoto, H, Koyama, H, Umehara, T. | Deposit date: | 2021-10-20 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles. Acs Med.Chem.Lett., 13, 2022
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4PGM
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2F78
| BenM effector binding domain with its effector benzoate | Descriptor: | BENZOIC ACID, HTH-type transcriptional regulator benM | Authors: | Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C. | Deposit date: | 2005-11-30 | Release date: | 2006-10-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol., 367, 2007
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7WI0
| SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
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5VNE
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