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7T7X
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BU of 7t7x by Molmil
Munc13-1 C1-C2B-MUN-C2C Upright conformation spanning two lipid bilayers
Descriptor: Protein unc-13 homolog A
Authors:Grushin, K, Sindelar, C.V.
Deposit date:2021-12-15
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T7V
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BU of 7t7v by Molmil
Munc13-1 C1-C2B-MUN-C2C Lateral conformation on lipid bilayer surface
Descriptor: Protein unc-13 homolog A
Authors:Grushin, K, Sindelar, C.V.
Deposit date:2021-12-15
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022
5NG5
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BU of 5ng5 by Molmil
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Descriptor: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ...
Authors:Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D.
Deposit date:2017-03-16
Release date:2017-04-19
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
2VSG
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BU of 2vsg by Molmil
A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei
Descriptor: VARIANT SURFACE GLYCOPROTEIN ILTAT 1.24
Authors:Blum, M.L, Down, J.A, Metcalf, P, Freymann, D.M, Wiley, D.C.
Deposit date:1998-11-19
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural motif in the variant surface glycoproteins of Trypanosoma brucei.
Nature, 362, 1993
6PQY
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BU of 6pqy by Molmil
Cryo-EM structure of HzTransib/TIR DNA transposon end complex (TEC)
Descriptor: DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*G)-3'), Putative DNA-mediated transposase
Authors:Liu, C, Yang, Y, Schatz, D.G.
Deposit date:2019-07-10
Release date:2019-10-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
6PR5
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BU of 6pr5 by Molmil
Cryo-EM structure of HzTransib strand transfer complex (STC)
Descriptor: DNA (30-MER), DNA (39-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*TP*CP*A)-3'), ...
Authors:Liu, C, Yang, Y, Schatz, D.G.
Deposit date:2019-07-10
Release date:2019-10-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
6J52
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BU of 6j52 by Molmil
Crystal structure of CARD-only protein in frog virus 3
Descriptor: Caspase recruitment domain-only protein
Authors:Park, H.H, Kwon, S.
Deposit date:2019-01-10
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Structural transformation-mediated dimerization of caspase recruitment domain revealed by the crystal structure of CARD-only protein in frog virus 3.
J. Struct. Biol., 205, 2019
3ZC0
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BU of 3zc0 by Molmil
Structure of AfC3PO - duplex RNA complex
Descriptor: 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP*GP*UP*CP*GP*AP*AP*UP*U)-3', AFTRAX, CHLORIDE ION, ...
Authors:Parizotto, E.A, Lowe, E.D, Parker, J.S.
Deposit date:2012-11-14
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.982 Å)
Cite:Structural Basis for Duplex RNA Recognition and Cleavage by Archaeoglobus Fulgidus C3Po.
Nat.Struct.Mol.Biol., 20, 2013
3ZC1
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BU of 3zc1 by Molmil
Crystal structure of AfC3PO
Descriptor: AFTRAX, MAGNESIUM ION
Authors:Parizotto, E.A, Lowe, E.D, Parker, J.S.
Deposit date:2012-11-14
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.269 Å)
Cite:Structural Basis for Duplex RNA Recognition and Cleavage by Archaeoglobus Fulgidus C3Po.
Nat.Struct.Mol.Biol., 20, 2013
1OO9
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BU of 1oo9 by Molmil
Orientation in Solution of MMP-3 Catalytic Domain and N-TIMP-1 from Residual Dipolar Couplings
Descriptor: Metalloproteinase inhibitor 1, Stromelysin-1
Authors:Arumugam, S, Van Doren, S.R.
Deposit date:2003-03-03
Release date:2003-07-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Global Orientation of Bound MMP-3 and N-TIMP-1 in Solution via Residual Dipolar Couplings
Biochemistry, 42, 2003
6PQU
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BU of 6pqu by Molmil
Cryo-EM structure of HzTransib/nicked TIR substrate DNA pre-reaction complex (PRC)
Descriptor: DNA (5'-D(P*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA-mediated transposase, ...
Authors:Liu, C, Yang, Y, Schatz, D.G.
Deposit date:2019-07-10
Release date:2019-10-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
6PQX
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BU of 6pqx by Molmil
Cryo-EM structure of HzTransib/nicked TIR substrate DNA hairpin forming complex (HFC)
Descriptor: CALCIUM ION, DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), ...
Authors:Liu, C, Yang, Y, Schatz, D.G.
Deposit date:2019-07-10
Release date:2019-10-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
6PQR
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BU of 6pqr by Molmil
Cryo-EM structure of HzTransib/intact TIR substrate DNA pre-reaction complex (PRC)
Descriptor: DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*GP*AP*GP*AP*TP*CP*TP*AP*G)-3'), DNA-mediated transposase, ...
Authors:Liu, C, Yang, Y, Schatz, D.G.
Deposit date:2019-07-09
Release date:2019-10-09
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of a RAG-like transposase during cut-and-paste transposition.
Nature, 575, 2019
6HFB
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BU of 6hfb by Molmil
Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.
Descriptor: CESIUM ION, Uncharacterized protein
Authors:Nonaka, T, Zakrzewska, S, Safarian, S, Michel, H.
Deposit date:2018-08-21
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Inward-facing conformation of a multidrug resistance MATE family transporter.
Proc.Natl.Acad.Sci.USA, 116, 2019
5UCW
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BU of 5ucw by Molmil
Cytochrome P411 P-4 A82L A78V F263L amination catalyst
Descriptor: NADPH-cytochrome P450 reductase 102A1V3, PROTOPORPHYRIN IX CONTAINING FE
Authors:Zhang, R.K, Buller, A.R, Arnold, F.H.
Deposit date:2016-12-22
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enantioselective, intermolecular benzylic C-H amination catalysed by an engineered iron-haem enzyme.
Nat Chem, 9, 2017
7S5F
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BU of 7s5f by Molmil
Crystal structure of mannose-6-phosphate reductase from celery (Apium graveolens) leaves with NADP+ and mannonic acid bound
Descriptor: D-MANNONIC ACID, Manose-6-phosphate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, Y, Bhayani, J.A, Romina, I.M, Hartman, M.D, Cereijo, A.E, Ballicora, M.A, Iglesias, A.A, Figueroa, C.M, Liu, D.
Deposit date:2021-09-10
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Determinants of Sugar Alcohol Biosynthesis in Plants: The Crystal Structures of Mannose-6-Phosphate and Aldose-6-Phosphate Reductases.
Plant Cell.Physiol., 63, 2022
7S5I
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BU of 7s5i by Molmil
Crystal structure of Aldose-6-phosphate reductase (Ald6PRase) from peach (Prunus persica) leaves
Descriptor: Sorbitol-6-phosphate dehydrogenase
Authors:Zheng, Y, Bhayani, J.A, Romina, I.M, Hartman, M.D, Cereijo, A.E, Ballicora, M.A, Iglesias, A.A, Figueroa, C.M, Liu, D.
Deposit date:2021-09-10
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural Determinants of Sugar Alcohol Biosynthesis in Plants: The Crystal Structures of Mannose-6-Phosphate and Aldose-6-Phosphate Reductases.
Plant Cell.Physiol., 63, 2022
4EGG
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BU of 4egg by Molmil
Computationally Designed Self-assembling tetrahedron protein, T310
Descriptor: GLYCEROL, Putative acetyltransferase SACOL2570
Authors:Sawaya, M.R, King, N.P, Sheffler, W, Baker, D, Yeates, T.O.
Deposit date:2012-03-30
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Computational design of self-assembling protein nanomaterials with atomic level accuracy.
Science, 336, 2012
3QNX
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BU of 3qnx by Molmil
Orthorhombic form of human IgA1 Fab fragment, sharing same Fv as IgG
Descriptor: Fab fragment of IMMUNOGLOBULIN A1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN A1 LIGHT CHAIN, GLYCEROL
Authors:Trajtenberg, F, Correa, A, Buschiazzo, A.
Deposit date:2011-02-09
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation
Acta Crystallogr.,Sect.D, 69, 2013
3G3F
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BU of 3g3f by Molmil
Crystal structure of the GluR6 ligand binding domain dimer with glutamate and NaCl at 1.38 Angstrom resolution
Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
Authors:Chaudhry, C, Mayer, M.L.
Deposit date:2009-02-02
Release date:2009-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.377 Å)
Cite:Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009
3WG6
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BU of 3wg6 by Molmil
Crystal structure of conjugated polyketone reductase C1 from Candida parapsilosis complexed with NADPH
Descriptor: Conjugated polyketone reductase C1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Qin, H.-M, Yamamura, A, Miyakawa, T, Maruoka, S, Ohtsuka, J, Nagata, K, Kataoka, M, Shimizu, S, Tanokura, M.
Deposit date:2013-07-28
Release date:2013-08-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of conjugated polyketone reductase (CPR-C1) from Candida parapsilosis IFO 0708 complexed with NADPH.
Proteins, 81, 2013
3G3H
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BU of 3g3h by Molmil
Crystal structure of the GluR6 ligand binding domain dimer K665R I749L Q753K mutant with glutamate and NaCl at 1.5 Angstrom resolution
Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
Authors:Chaudhry, C, Mayer, M.L.
Deposit date:2009-02-02
Release date:2009-06-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009
4ITR
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BU of 4itr by Molmil
Crystal Structure of IbpAFic2-H3717A in complex with adenylylated Cdc42
Descriptor: ADENOSINE MONOPHOSPHATE, Adenosine monophosphate-protein transferase and cysteine protease IbpA, Cell division control protein 42 homolog, ...
Authors:Xiao, J, Dixon, J.E.
Deposit date:2013-01-18
Release date:2013-02-20
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of Fic-mediated adenylylation.
Nat.Struct.Mol.Biol., 17, 2010
3PUY
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BU of 3puy by Molmil
Crystal Structure of an outward-facing MBP-Maltose transporter complex bound to AMP-PNP after crystal soaking of the pretranslocation state
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Fused maltose transport subunit, ATP-binding component of ABC superfamily; regulatory protein, ...
Authors:Oldham, M.L, Chen, J.
Deposit date:2010-12-06
Release date:2011-05-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the maltose transporter in a pretranslocation intermediate state.
Science, 332, 2011
3G3K
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BU of 3g3k by Molmil
Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K E757Q mutant with glutamate and NaCl at 1.24 Angstrom resolution
Descriptor: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ...
Authors:Chaudhry, C, Mayer, M.L.
Deposit date:2009-02-02
Release date:2009-06-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Embo J., 28, 2009

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