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4BFY	Crystal structure of Mycobacterium tuberculosis PanK in complex with a biaryl inhibitory compound (2a) and phosphate Descriptor: 2-[4-(4-cyanophenyl)-3-[(4-pyridin-2-ylpiperazin-1-yl)methyl]phenoxy]acetic acid, PANTOTHENATE KINASE, PHOSPHATE ION Authors: Bjorkelid, C, Bergfors, T, Jones, T.A. Deposit date: 2013-03-22 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
4BFZ	Crystal structure of Mycobacterium tuberculosis PanK in complex with a biaryl inhibitory compound (2b) and phosphate Descriptor: 2-[4-(4-CYANOPHENYL)-3-{[4-(PYRIDIN-2-YL)PIPERAZIN-1-YL]METHYL}PHENOXY]-N-METHYLACETAMIDE, PANTOTHENATE KINASE, PHOSPHATE ION Authors: Bjorkelid, C, Bergfors, T, Jones, T.A. Deposit date: 2013-03-22 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
4BFT	Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1b) and phosphate Descriptor: 2-chloro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide, PANTOTHENATE KINASE, PHOSPHATE ION Authors: Bjorkelid, C, Bergfors, T, Jones, T.A. Deposit date: 2013-03-22 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
4BFW	Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1e) and phosphate Descriptor: N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-[(4-fluorophenyl)methyl]-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION Authors: Bjorkelid, C, Bergfors, T, Jones, T.A. Deposit date: 2013-03-22 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
4BFV	Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1d) and phosphate Descriptor: N-[1-(4-methyl-5-{[2-(2-methylphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION Authors: Bjorkelid, C, Bergfors, T, Jones, T.A. Deposit date: 2013-03-22 Release date: 2013-05-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
3ELF	Structural Characterization of tetrameric Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase - substrate binding and catalysis mechanism of a class IIa bacterial aldolase Descriptor: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), Fructose-bisphosphate aldolase, SODIUM ION, ... Authors: Pegan, S, Rukseree, K, Franzblau, S.G, Mesecar, A.D. Deposit date: 2008-09-22 Release date: 2009-02-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.31 Å) Cite: Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis J.Mol.Biol., 386, 2009
3EKL	Structural Characterization of tetrameric Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase - substrate binding and catalysis mechanism of a class IIa bacterial aldolase Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, SODIUM ION, ... Authors: Pegan, S, Rukseree, K, Franzblau, S.G, Mesecar, A.D. Deposit date: 2008-09-19 Release date: 2009-02-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis J.Mol.Biol., 386, 2009
2QHF	Mycobacterium tuberculosis Chorismate synthase in complex with NCA Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ... Authors: Bruning, M, Bourenkov, G.P, Strizhov, N.I, Bartunik, H.D. Deposit date: 2007-07-02 Release date: 2008-07-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Mycobacterium tuberculosis Chorismate synthase in complex with NCA To be Published
2BNN	The structure of Hydroxypropylphosphonic acid epoxidase from S. wedmorenis in complex with fosfomycin Descriptor: EPOXIDASE, FOSFOMYCIN, ZINC ION Authors: McLuskey, K, Cameron, S, Hunter, W.N. Deposit date: 2005-03-29 Release date: 2005-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure and Reactivity of Hydroxypropylphosphonic Acid Epoxidase in Fosfomycin Biosynthesis by a Cation- and Flavin-Dependent Mechanism. Proc.Natl.Acad.Sci.USA, 102, 2005
3FGN	Crystal structure of dethiobiotin synthetase in Mycobacterium tuberculosis Descriptor: Dethiobiotin synthetase Authors: Dey, S, Sacchettini, J.C. Deposit date: 2008-12-08 Release date: 2009-06-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry, 49, 2010
3FPA	Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase complexed with dethiobiotin and phosphate Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, Dethiobiotin synthetase, MAGNESIUM ION, ... Authors: Dey, S, Sacchettini, J.C. Deposit date: 2009-01-04 Release date: 2009-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase. Biochemistry, 49, 2010
2I6U	Crystal Structure of Ornithine Carbamoyltransferase complexed with Carbamoyl Phosphate and L-Norvaline from Mycobacterium tuberculosis (Rv1656) at 2.2 A Descriptor: NORVALINE, Ornithine carbamoyltransferase, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... Authors: Sankaranarayanan, R, Moradian, F, Cherney, L.T, Garen, C, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC) Deposit date: 2006-08-29 Release date: 2007-06-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism J.Mol.Biol., 375, 2008
2C8T	The 3.0 A Resolution Structure of Caseinolytic Clp Protease 1 from Mycobacterium tuberculosis Descriptor: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 Authors: Ingvarsson, H, Hogbom, M, Jones, T.A, Unge, T. Deposit date: 2005-12-07 Release date: 2007-02-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1. Acta Crystallogr.,Sect.D, 63, 2007
4GQU	Crystal structure of HisB from Mycobacterium tuberculosis Descriptor: 1,2-ETHANEDIOL, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION Authors: Ahangar, M.S, Vyas, R, Nasir, N, Biswal, B.K. Deposit date: 2012-08-24 Release date: 2013-08-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Crystal structures of the native, substrate- bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase Acta Crystallogr.,Sect.D, 2013
2I1U	Mycobacterium tuberculosis thioredoxin C Descriptor: Thioredoxin Authors: Hall, G, McEwan, P.A, Emsley, J. Deposit date: 2006-08-15 Release date: 2006-12-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structure of Mycobacterium tuberculosisthioredoxin C. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
8PNL	Outward-open conformation of a Major Facilitator Superfamily (MFS) transporter MHAS2168, a homologue of Rv1410 from M. tuberculosis, in complex with an alpaca nanobody Descriptor: Nb_H2, Putative triacylglyceride transporter Authors: Remm, S, Schoeppe, J, Hutter, C.A.J, Gonda, I, Seeger, M.A. Deposit date: 2023-06-30 Release date: 2023-10-18 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410. Nat Commun, 14, 2023
4HVJ	Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis in complex with AMP Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-11-06 Release date: 2012-11-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mycobacterium tuberculosis Rv2179c Protein Establishes a New Exoribonuclease Family with Broad Phylogenetic Distribution. J.Biol.Chem., 289, 2014
2V2K	THE CRYSTAL STRUCTURE OF FDXA, A 7FE FERREDOXIN FROM MYCOBACTERIUM SMEGMATIS Descriptor: ACETATE ION, FE3-S4 CLUSTER, FERREDOXIN Authors: Ricagno, S, de Rosa, M, Aliverti, A, Zanetti, G, Bolognesi, M. Deposit date: 2007-06-06 Release date: 2007-07-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The Crystal Structure of Fdxa, a 7Fe Ferredoxin from Mycobacterium Smegmatis. Biochem.Biophys.Res.Commun., 360, 2007
3TSC	Crystal structure of short chain dehydrogenase MAP_2410 from Mycobacterium paratuberculosis bound to NAD Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-09-12 Release date: 2011-10-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
4OOF	M. tuberculosis 1-deoxy-d-xylulose-5-phosphate reductoisomerase W203F mutant bound to fosmidomycin and NADPH Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, MANGANESE (II) ION, ... Authors: Allen, C.L, Kholodar, S.A, Murkin, A.S, Gulick, A.M. Deposit date: 2014-01-31 Release date: 2014-06-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Alteration of the Flexible Loop in 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase Boosts Enthalpy-Driven Inhibition by Fosmidomycin. Biochemistry, 53, 2014
4OTK	A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form Descriptor: CHLORIDE ION, MALONATE ION, Mycobacterial Enzyme Rv2971 Authors: Shahine, A, Beddoe, T. Deposit date: 2014-02-13 Release date: 2014-05-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A structural characterization of the isoniazid Mycobacterium tuberculosis drug target, Rv2971, in its unliganded form Acta Crystallogr.,Sect.F, 70, 2014
1FJA	NMR STUDY OF DEOXYRIBONUCLEIC ACID COMPLEXED WITH ACTINOMYCIN D Descriptor: ACTINOMYCIN D, DNA (5'-D(*AP*AP*GP*CP*GP*CP*TP*T)-3') Authors: Chen, H, Liu, X, Patel, D.J. Deposit date: 1995-12-15 Release date: 1996-06-10 Last modified: 2024-07-10 Method: SOLUTION NMR Cite: DNA Bending and Unwinding Associated with Actinomycin D Antibiotics Bound to Partially Overlapping Sites on DNA. J.Mol.Biol., 258, 1996
3T7C	Crystal structure of carveol dehydrogenase from Mycobacterium avium bound to NAD Descriptor: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-07-29 Release date: 2011-08-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Sci Rep, 7, 2017
4HEC	Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis Descriptor: MAGNESIUM ION, Putative uncharacterized protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-10-03 Release date: 2012-10-17 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Mycobacterium tuberculosis Rv2179c Protein Establishes a New Exoribonuclease Family with Broad Phylogenetic Distribution. J.Biol.Chem., 289, 2014
1GCB	GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL) Descriptor: GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ... Authors: Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C. Deposit date: 1995-07-18 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269, 1995

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