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1EF3
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FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE
Descriptor: (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oka, M, Matsumoto, Y, Sugiyama, S, Tsuruta, N, Matsushima, M.
Deposit date:2000-02-06
Release date:2001-02-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography.
J.Med.Chem., 43, 2000
1EF4
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SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor: DNA-DIRECTED RNA POLYMERASE, ZINC ION
Authors:Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-02-07
Release date:2000-06-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EF5
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SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL
Descriptor: RGL
Authors:Kigawa, T, Endo, M, Ito, Y, Shirouzu, M, Kikuchi, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2000-02-07
Release date:2000-02-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the Ras-binding domain of RGL.
FEBS Lett., 441, 1998
1EF7
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CRYSTAL STRUCTURE OF HUMAN CATHEPSIN X
Descriptor: CATHEPSIN X
Authors:Guncar, G, Klemencic, I, Turk, B, Turk, V, Karaoglanovic-Carmona, A, Juliano, L, Turk, D.
Deposit date:2000-02-07
Release date:2000-03-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease.
Structure Fold.Des., 8, 2000
1EF8
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CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE
Descriptor: METHYLMALONYL COA DECARBOXYLASE, NICKEL (II) ION
Authors:Benning, M.M, Haller, T, Gerlt, J.A, Holden, H.M.
Deposit date:2000-02-07
Release date:2000-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli.
Biochemistry, 39, 2000
1EF9
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THE CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE COMPLEXED WITH 2S-CARBOXYPROPYL COA
Descriptor: 2-CARBOXYPROPYL-COENZYME A, METHYLMALONYL COA DECARBOXYLASE
Authors:Benning, M.M, Haller, T, Gerlt, J.A, Holden, H.M.
Deposit date:2000-02-07
Release date:2000-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli.
Biochemistry, 39, 2000
1EFA
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CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
Descriptor: 2-nitrophenyl beta-D-fucopyranoside, DNA (5'-D(*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), LAC REPRESSOR
Authors:Bell, C.E, Lewis, M.
Deposit date:2000-02-07
Release date:2000-03-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A closer view of the conformation of the Lac repressor bound to operator.
Nat.Struct.Biol., 7, 2000
1EFC
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INTACT ELONGATION FACTOR FROM E.COLI
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (ELONGATION FACTOR)
Authors:Song, H, Parsons, M.R, Rowsell, S, Leonard, G, Phillips, S.E.V.
Deposit date:1998-11-24
Release date:1999-03-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution.
J.Mol.Biol., 285, 1999
1EFD
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PERIPLASMIC FERRIC SIDEROPHORE BINDING PROTEIN FHUD COMPLEXED WITH GALLICHROME
Descriptor: FERRICHROME-BINDING PERIPLASMIC PROTEIN, GALLICHROME
Authors:Clarke, T.E, Ku, S.-Y, Dougan, D.R, Vogel, H.J, Tari, L.W.
Deposit date:2000-02-07
Release date:2000-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of the ferric siderophore binding protein FhuD complexed with gallichrome.
Nat.Struct.Biol., 7, 2000
1EFE
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AN ACTIVE MINI-PROINSULIN, M2PI
Descriptor: MINI-PROINSULIN
Authors:Cho, Y, Chang, S.G, Choi, K.D, Shin, H, Ahn, B, Kim, K.S.
Deposit date:2000-02-08
Release date:2000-03-17
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity
J.Biochem.Mol.Biol., 33, 2000
1EFG
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THE CRYSTAL STRUCTURE OF ELONGATION FACTOR G COMPLEXED WITH GDP, AT 2.7 ANGSTROMS RESOLUTION
Descriptor: ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE
Authors:Czworkowski, J, Wang, J, Steitz, T.A, Moore, P.B.
Deposit date:1994-10-17
Release date:1995-02-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.
EMBO J., 13, 1994
1EFH
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CRYSTAL STRUCTURE OF THE HUMAN HYDROXYSTEROID SULFOTRANSFERASE IN THE PRESENCE OF PAP
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, HYDROXYSTEROID SULFOTRANSFERASE
Authors:Pedersen, L.C, Petrotchenko, E.V, Negishi, M.
Deposit date:2000-02-08
Release date:2000-09-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase.
FEBS Lett., 475, 2000
1EFI
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HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH PARA-AMINOPHENYL-ALPHA-D-GALACTOPYRANOSIDE
Descriptor: 4-aminophenyl alpha-D-galactopyranoside, PROTEIN (HEAT-LABILE ENTEROTOXIN B CHAIN)
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:2000-02-08
Release date:2000-02-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
Acta Crystallogr.,Sect.D, 57, 2001
1EFK
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STRUCTURE OF HUMAN MALIC ENZYME IN COMPLEX WITH KETOMALONATE
Descriptor: ALPHA-KETOMALONIC ACID, MAGNESIUM ION, MALIC ENZYME, ...
Authors:Yang, Z, Floyd, D.L, Loeber, G, Tong, L.
Deposit date:2000-02-09
Release date:2000-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
Nat.Struct.Biol., 7, 2000
1EFL
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HUMAN MALIC ENZYME IN A QUATERNARY COMPLEX WITH NAD, MG, AND TARTRONATE
Descriptor: MAGNESIUM ION, MALIC ENZYME, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Yang, Z, Floyd, D.L, Loeber, G, Tong, L.
Deposit date:2000-02-09
Release date:2000-03-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
Nat.Struct.Biol., 7, 2000
1EFM
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STRUCTURE OF THE GDP DOMAIN OF EF-TU AND LOCATION OF THE AMINO ACIDS HOMOLOGOUS TO RAS ONCOGENE PROTEINS
Descriptor: ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Jurnak, F.
Deposit date:1987-05-29
Release date:1987-07-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins.
Science, 230, 1985
1EFN
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HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
Descriptor: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1996-06-29
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996
1EFO
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CRYSTAL STRUCTURE OF AN ADENINE BULGE IN THE RNA CHAIN OF A DNA/RNA HYBRID, D(CTCCTCTTC)/R(GAAGAGAGAG)
Descriptor: DNA (5'-D(*CP*TP*CP*CP*TP*CP*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3')
Authors:Sudarsanakumar, C, Xiong, Y, Sundaralingam, M.
Deposit date:2000-02-09
Release date:2000-05-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an adenine bulge in the RNA chain of a DNA.RNA hybrid, d(CTCCTCTTC).r(gaagagagag).
J.Mol.Biol., 299, 2000
1EFP
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ELECTRON TRANSFER FLAVOPROTEIN (ETF) FROM PARACOCCUS DENITRIFICANS
Descriptor: ADENOSINE MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (ELECTRON TRANSFER FLAVOPROTEIN)
Authors:Roberts, D.L, Salazar, D, Fulmer, J.P, Frerman, F.E, Kim, J.J.-P.
Deposit date:1998-12-18
Release date:1999-08-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Paracoccus denitrificans electron transfer flavoprotein: structural and electrostatic analysis of a conserved flavin binding domain.
Biochemistry, 38, 1999
1EFQ
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Q38D mutant of LEN
Descriptor: KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), URANYL (VI) ION, ZINC ION
Authors:Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M.
Deposit date:2000-02-09
Release date:2001-02-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
1EFR
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BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE PEPTIDE ANTIBIOTIC EFRAPEPTIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT ALPHA, BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT BETA, ...
Authors:Abrahams, J.P, Buchanan, S.K, Van Raaij, M.J, Fearnley, I.M, Leslie, A.G.W, Walker, J.E.
Deposit date:1996-05-24
Release date:1997-02-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Structure of Bovine F1-ATPase Complexed with the Peptide Antibiotic Efrapeptin.
Proc.Natl.Acad.Sci.USA, 93, 1996
1EFS
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CONFORMATION OF A DNA-RNA HYBRID
Descriptor: DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*UP*CP*UP*UP*CP*CP*UP*CP*UP*C)-3')
Authors:Larue, V, Hantz, E.
Deposit date:2000-02-10
Release date:2000-03-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution conformation of an RNA--DNA hybrid duplex containing a pyrimidine RNA strand and a purine DNA strand.
Int.J.Biol.Macromol., 28, 2001
1EFT
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THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION
Descriptor: ELONGATION FACTOR TU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Kjeldgaard, M, Nissen, P, Thirup, S, Nyborg, J.
Deposit date:1993-08-24
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation.
Structure, 1, 1993
1EFU
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ELONGATION FACTOR COMPLEX EF-TU/EF-TS FROM ESCHERICHIA COLI
Descriptor: ELONGATION FACTOR TS, ELONGATION FACTOR TU
Authors:Kawashima, T, Berthet-Colominas, C, Wulff, M, Cusack, S, Leberman, R.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution.
Nature, 379, 1996
1EFV
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THREE-DIMENSIONAL STRUCTURE OF HUMAN ELECTRON TRANSFER FLAVOPROTEIN TO 2.1 A RESOLUTION
Descriptor: ADENOSINE MONOPHOSPHATE, ELECTRON TRANSFER FLAVOPROTEIN, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Roberts, D.L, Frerman, F.E, Kim, J.J.P.
Deposit date:1996-10-16
Release date:1997-12-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of human electron transfer flavoprotein to 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996

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