1S2U
 
 | | Crystal structure of the D58A phosphoenolpyruvate mutase mutant protein | | Descriptor: | DI(HYDROXYETHYL)ETHER, Phosphoenolpyruvate phosphomutase | | Authors: | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | Deposit date: | 2004-01-11 | | Release date: | 2004-05-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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4R3A
 | | Erythrobacter litoralis EL346 blue-light activated histidine kinase | | Descriptor: | Blue-light-activated histidine kinase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Tomchick, D.R, Rivera-Cancel, G, Gardner, K.H. | | Deposit date: | 2014-08-14 | | Release date: | 2014-12-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1S5K
 | | Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 1) | | Descriptor: | COENZYME A, SULFATE ION, aminoglycoside 6'-N-acetyltransferase | | Authors: | Vetting, M.W, Magnet, S, Nieves, E, Roderick, S.L, Blanchard, J.S. | | Deposit date: | 2004-01-21 | | Release date: | 2004-05-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones
Chem.Biol., 11, 2004
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6C30
 | | Mycobacterium smegmatis RimJ (apo form) | | Descriptor: | CHLORIDE ION, GLYCEROL, GNAT family acetyltransferase | | Authors: | Favrot, L, Hegde, S.S, Blanchard, J.S. | | Deposit date: | 2018-01-09 | | Release date: | 2019-01-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.397 Å) | | Cite: | Structural Characterization of Mycobacterium smegmatis RimJ, an N-acetyltransferase protein
To Be Published
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1Y9W
 | | Structural Genomics, 1.9A crystal structure of an acetyltransferase from Bacillus cereus ATCC 14579 | | Descriptor: | Acetyltransferase | | Authors: | Zhang, R, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2004-12-16 | | Release date: | 2005-02-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | 1.9A crystal structure of an acetyltransferase from Bacillus cereus ATCC 14579
To be Published, 2005
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3AQB
 | | M. luteus B-P 26 heterodimeric hexaprenyl diphosphate synthase in complex with magnesium | | Descriptor: | CHLORIDE ION, Component A of hexaprenyl diphosphate synthase, Component B of hexaprenyl diphosphate synthase, ... | | Authors: | Sasaki, D, Fujihashi, M, Okuyama, N, Kobayashi, Y, Noike, M, Koyama, T, Miki, K. | | Deposit date: | 2010-10-28 | | Release date: | 2010-11-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of heterodimeric hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26 reveals that the small subunit is directly involved in the product chain length regulation.
J.Biol.Chem., 286, 2011
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1JG0
 | | Crystal structure of Escherichia coli thymidylate synthase complexed with 2'-deoxyuridine-5'-monophosphate and N,O-didansyl-L-tyrosine | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, N,O-DIDANSYL-L-TYROSINE, thymidylate synthase | | Authors: | Fritz, T.A, Tondi, D, Finer-Moore, J.S, Costi, M.P, Stroud, R.M. | | Deposit date: | 2001-06-22 | | Release date: | 2002-02-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Predicting and harnessing protein flexibility in the design of species-specific inhibitors of thymidylate synthase.
Chem.Biol., 8, 2001
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6BJL
 | | Human ABO(H) blood group glycosyltransferase GTB D302L mutant | | Descriptor: | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ... | | Authors: | Gagnon, S.M.L, Legg, M.S.G, Evans, S.V. | | Deposit date: | 2017-11-06 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
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1YBG
 | | MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid | | Descriptor: | N-METHYL-N-{2-[(2-NAPHTHYLSULFONYL)AMINO]-5-[(2-NAPHTHYLSULFONYL)OXY]BENZOYL}-L-ASPARTIC ACID, UDP-N-acetylglucosamine 1-carboxyvinyltransferase | | Authors: | Eschenburg, S, Priestman, M.A, Abdul-Latif, F.A, Delachaume, C, Fassy, F, Schonbrunn, E. | | Deposit date: | 2004-12-20 | | Release date: | 2005-02-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA).
J.Biol.Chem., 280, 2005
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4R7U
 | | Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin | | Descriptor: | SODIUM ION, TETRAETHYLENE GLYCOL, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... | | Authors: | Nocek, B, Maltseva, N, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2014-08-28 | | Release date: | 2014-09-24 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin
To be Published
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4R8E
 | | Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Yersinia pestis | | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | | Authors: | Himiari, Z, Nanson, J.D, Swarbrick, C.M.D, Forwood, J.K. | | Deposit date: | 2014-09-02 | | Release date: | 2014-12-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.
Sci Rep, 5, 2015
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4LD7
 | | Crystal structure of AnaPT from Neosartorya fischeri | | Descriptor: | Dimethylallyl tryptophan synthase, SODIUM ION, TRIHYDROGEN THIODIPHOSPHATE | | Authors: | Zocher, G, Stehle, T. | | Deposit date: | 2013-06-24 | | Release date: | 2013-12-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Catalytic Mechanism of Stereospecific Formation of cis-Configured Prenylated Pyrroloindoline Diketopiperazines by Indole Prenyltransferases.
Chem.Biol., 20, 2013
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1XVT
 | | Crystal Structure of Native CaiB in complex with coenzyme A | | Descriptor: | COENZYME A, Crotonobetainyl-CoA:carnitine CoA-transferase | | Authors: | Rangarajan, E.S, Li, Y, Iannuzzi, P, Cygler, M, Matte, A. | | Deposit date: | 2004-10-28 | | Release date: | 2005-03-15 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Escherichia coli Crotonobetainyl-CoA: Carnitine CoA-Transferase (CaiB) and Its Complexes with CoA and Carnitinyl-CoA.
Biochemistry, 44, 2005
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4IN6
 | | (M)L214A mutant of the Rhodobacter sphaeroides Reaction Center | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ... | | Authors: | Saer, R.G, Hardjasa, A, Murphy, M.E.P, Beatty, J.T. | | Deposit date: | 2013-01-04 | | Release date: | 2013-05-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Role of Rhodobacter sphaeroides Photosynthetic Reaction Center Residue M214 in the Composition, Absorbance Properties, and Conformations of HA and BA Cofactors.
Biochemistry, 52, 2013
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1XET
 | | Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA | | Descriptor: | 3-(1H-INDOL-3-YL)-2-OXOPROPANOIC ACID, Dihydropinosylvin synthase, METHYLMALONYL-COENZYME A | | Authors: | Ng, S.H, Chirgadze, D, Spiteller, D, Li, T.L, Spencer, J.B, Blundell, T.L. | | Deposit date: | 2004-09-12 | | Release date: | 2006-04-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA
To be Published
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1JBO
 | | The 1.45A Three-Dimensional Structure of c-Phycocyanin from the Thermophylic Cyanobacterium Synechococcus elongatus | | Descriptor: | C-Phycocyanin alpha chain, C-Phycocyanin beta chain, PHYCOCYANOBILIN | | Authors: | Nield, J, Rizkallah, P.J, Barber, J, Chayen, N.E. | | Deposit date: | 2002-05-02 | | Release date: | 2003-03-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The 1.45A three-dimensional structure of C-phycocyanin from the
thermophilic cyanobacterium Synechococcus elongatus
J.STRUCT.BIOL., 141, 2003
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4LMA
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4QVH
 | | Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein | | Descriptor: | CITRATE ANION, COENZYME A, GLYCEROL, ... | | Authors: | Jung, J, Bashiri, G, Johnston, J.M, Baker, E.N. | | Deposit date: | 2014-07-15 | | Release date: | 2014-12-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.
J.Struct.Biol., 188, 2014
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1S7L
 | | RimL- Ribosomal L7/L12 alpha-N-protein acetyltransferase in complex with Coenzyme A (CoA-Cys134 Disulfide) | | Descriptor: | COENZYME A, SULFATE ION, acetyl transferase | | Authors: | Vetting, M.W, de Carvalho, L.P, Roderick, S.L, Blanchard, J.S. | | Deposit date: | 2004-01-29 | | Release date: | 2005-03-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A novel dimeric structure of the RimL Nalpha-acetyltransferase from Salmonella typhimurium.
J.Biol.Chem., 280, 2005
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4R9M
 | | Crystal structure of spermidine N-acetyltransferase from Escherichia coli | | Descriptor: | MAGNESIUM ION, Spermidine N(1)-acetyltransferase | | Authors: | Filippova, E.V, Minasov, G, Kiryukhina, O, Shuvalova, L, Grimshaw, S, Wolfe, A.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2014-09-05 | | Release date: | 2014-11-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Analysis of crystalline and solution states of ligand-free spermidine N-acetyltransferase (SpeG) from Escherichia coli.
Acta Crystallogr D Struct Biol, 75, 2019
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6C9S
 | | Mycobacterium tuberculosis adenosine kinase bound to (2R,3R,4S,5R)-2-(6-([1,1'-biphenyl]-4-ylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | | Descriptor: | 6-[([1,1'-biphenyl]-4-yl)ethynyl]-9-beta-D-ribofuranosyl-9H-purine, Adenosine kinase, SODIUM ION, ... | | Authors: | Crespo, R.A, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2018-01-28 | | Release date: | 2019-05-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
J.Med.Chem., 62, 2019
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1S3Z
 | | Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and Ribostamycin | | Descriptor: | COENZYME A, NICKEL (II) ION, RIBOSTAMYCIN, ... | | Authors: | Vetting, M.W, Magnet, S, Nieves, E, Roderick, S.L, Blachard, J.S. | | Deposit date: | 2004-01-14 | | Release date: | 2004-05-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones
Chem.Biol., 11, 2004
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4FOG
 | | Crystal Structure of Mtb ThyA in Complex with 5-Fluoro-dUMP and 5-methyltetrahydrofolic acid | | Descriptor: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Thymidylate synthase | | Authors: | Reddy, M.C.M, Bruning, J.B, Harshbarger, W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2012-06-20 | | Release date: | 2013-08-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: Insights into the selectivity and mode of inhibition
To be Published
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6BJB
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4P0V
 | | Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione | | Descriptor: | (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | | Authors: | Liu, Y.L, Oldfield, E. | | Deposit date: | 2014-02-23 | | Release date: | 2014-07-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site.
Proc.Natl.Acad.Sci.USA, 111, 2014
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