4R7U

Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin

Summary for 4R7U

• Entry DOI: 10.2210/pdb4r7u/pdb
• Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, TETRAETHYLENE GLYCOL, [(1R)-1-hydroxypropyl]phosphonic acid, ... (6 entities in total)
• Functional Keywords: mura, fosfomycin, peptidoglycan, amino sugar and nucleotide sugar metabolism, peptidoglycan biosynthesis, structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, udp-n-acetylglucosamine 1-carboxyvinyltransferase, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Vibrio cholerae O1 biovar El Tor str. N16961
• Cellular location: Cytoplasm : Q9KP62
• Total number of polymer chains: 4
• Total formula weight: 183345.22

Authors

Nocek, B.,Maltseva, N.,Anderson, W.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-08-28, release date: 2014-09-24, Last modification date: 2017-11-22)

• Primary citation: Nocek, B.,Maltseva, N.,Anderson, W.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin; To be Published,

Experimental method

X-RAY DIFFRACTION (2.45 Å)