4R7U
Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | polymer | 422 | 45011.6 | 4 | UniProt (Q9KP62) Pfam (PF00275) | Vibrio cholerae O1 biovar El Tor str. N16961 | Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT |
| 2 | E (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 3 | F, J, M, Q (A, B, C, D) | [(1R)-1-hydroxypropyl]phosphonic acid | non-polymer | 140.1 | 4 | Chemie (FFQ) | |||
| 4 | G, I, L, P (A, B, C, D) | URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | non-polymer | 607.4 | 4 | Chemie (UD1) | |||
| 5 | H, K, N, O, R (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 6 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 419 (UniProt: Q9KP62)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 180046.3 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3298.9 | |
| All* | Total formula weight | 183345.2 |
