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2ABL	SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE Descriptor: ABL TYROSINE KINASE Authors: Nam, H.-J, Frederick, C.A. Deposit date: 1996-11-17 Release date: 1997-09-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism. Structure, 4, 1996
1YCS	P53-53BP2 COMPLEX Descriptor: 53BP2, P53, ZINC ION Authors: Gorina, S, Pavletich, N.P. Deposit date: 1996-09-30 Release date: 1997-11-19 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science, 274, 1996
1NLP	STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: C-SRC, NL2 (MN8-MN1-PLPPLP) Authors: Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L. Deposit date: 1996-08-04 Release date: 1997-01-27 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis. Chem.Biol., 3, 1996
1NLO	STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: C-SRC, NL1 (MN7-MN2-MN1-PLPPLP) Authors: Feng, S, Kapoor, T.M, Shirai, F, Combs, A.P, Schreiber, S.L. Deposit date: 1996-08-04 Release date: 1997-01-27 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis. Chem.Biol., 3, 1996
1EFN	HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN Descriptor: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION Authors: Lee, C.-H, Kuriyan, J. Deposit date: 1996-06-29 Release date: 1997-01-11 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell(Cambridge,Mass.), 85, 1996
1NYG	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, FAMILY OF 20 STRUCTURES Descriptor: FYN Authors: Morton, C.J, Pugh, D.J.R, Campbell, I.D. Deposit date: 1996-04-22 Release date: 1996-11-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure and peptide binding of the SH3 domain from human Fyn. Structure, 4, 1996
1NYF	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE Descriptor: FYN Authors: Morton, C.J, Pugh, D.J.R, Campbell, I.D. Deposit date: 1996-04-22 Release date: 1996-11-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure and peptide binding of the SH3 domain from human Fyn. Structure, 4, 1996
1TUD	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 Descriptor: ALPHA-SPECTRIN Authors: Viguera, A.R, Serrano, L, Wilmanns, M. Deposit date: 1996-02-29 Release date: 1996-08-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.77 Å) Cite: The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics. J.Mol.Biol., 247, 1995
1TUC	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20 Descriptor: ALPHA-SPECTRIN Authors: Wilmanns, M, Serrano, L, Viguera, A.R. Deposit date: 1996-02-29 Release date: 1996-08-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.02 Å) Cite: The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics. J.Mol.Biol., 247, 1995
1QWF	C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND VSL12 Descriptor: TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC, VAL-SER-LEU-ALA-ARG-ARG-PRO-LEU-PRO-PRO-LEU-PRO Authors: Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L. Deposit date: 1995-11-09 Release date: 1996-03-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Proc.Natl.Acad.Sci.USA, 92, 1995
1QWE	C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND APP12 Descriptor: ALA-PRO-PRO-LEU-PRO-PRO-ARG-ASN-ARG-PRO-ARG-LEU, TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC Authors: Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L. Deposit date: 1995-11-09 Release date: 1996-03-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Proc.Natl.Acad.Sci.USA, 92, 1995
1ABO	CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE Descriptor: 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ABL TYROSINE KINASE, ... Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1ABQ	CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN Descriptor: ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1FYN	PHOSPHOTRANSFERASE Descriptor: 3BP-2, PHOSPHOTRANSFERASE FYN Authors: Musacchio, A, Saraste, M, Wilmanns, M. Deposit date: 1995-05-17 Release date: 1996-11-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1SEM	STRUCTURAL DETERMINANTS OF PEPTIDE-BINDING ORIENTATION AND OF SEQUENCE SPECIFICITY IN SH3 DOMAINS Descriptor: 10-RESIDUE PROLINE-RICH PEPTIDE FROM MSOS (ACE-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG), SEM-5 Authors: Lim, W.A, Richards, F.M, Fox, R.O. Deposit date: 1995-03-28 Release date: 1995-07-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains. Nature, 372, 1994
1GRI	GRB2 Descriptor: GROWTH FACTOR BOUND PROTEIN 2 Authors: Maignan, S, Arnoux, B, Ducruix, A. Deposit date: 1995-02-28 Release date: 1996-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal structure of the mammalian Grb2 adaptor. Science, 268, 1995
1CKB	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
1CKA	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
1LCK	SH3-SH2 DOMAIN FRAGMENT OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 10 RESIDUE SYNTHETIC PHOSPHOTYROSYL PEPTIDE TEGQPYQPQPA Descriptor: P56==LCK== TYROSINE KINASE, TAIL PHOSPHOPEPTIDE TEGQ(PHOSPHO)YQPQPA Authors: Eck, M, Harrison, S. Deposit date: 1994-12-12 Release date: 1995-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the regulatory domains of the Src-family tyrosine kinase Lck. Nature, 368, 1994
1RLQ	TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY) Authors: Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. Deposit date: 1994-10-10 Release date: 1995-02-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1994
1PRM	TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) Authors: Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. Deposit date: 1994-10-10 Release date: 1995-02-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1994
1PRL	TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR) Authors: Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. Deposit date: 1994-10-10 Release date: 1995-02-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1994
1RLP	TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY) Authors: Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. Deposit date: 1994-10-10 Release date: 1995-02-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science, 266, 1994
1GBR	ORIENTATION OF PEPTIDE FRAGMENTS FROM SOS PROTEINS BOUND TO THE N-TERMINAL SH3 DOMAIN OF GRB2 DETERMINED BY NMR SPECTROSCOPY Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, SOS-A PEPTIDE Authors: Wittekind, M, Mapelli, C, Farmer, B.T, Suen, K.-L, Goldfarb, V, Tsao, J, Lavoie, T, Barbacid, M, Meyers, C.A, Mueller, L. Deposit date: 1994-08-12 Release date: 1995-01-26 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy. Biochemistry, 33, 1994
1HSQ	SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA Descriptor: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN) Authors: Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F. Deposit date: 1994-06-13 Release date: 1994-08-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the SH3 domain of phospholipase C-gamma. Cell(Cambridge,Mass.), 72, 1993

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