Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5VKD
DownloadVisualize
BU of 5vkd by Molmil
Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment
Descriptor: Fab Heavy Chain, Fab light chain, Nucleoprotein
Authors:Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S.
Deposit date:2017-04-21
Release date:2018-04-25
Last modified:2022-11-16
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
5W2B
DownloadVisualize
BU of 5w2b by Molmil
Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment
Descriptor: Fab Heavy Chain, Fab Light Chain, Nucleoprotein
Authors:Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S.
Deposit date:2017-06-06
Release date:2018-06-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
6LYW
DownloadVisualize
BU of 6lyw by Molmil
Structural insight into the biological functions of Arabidopsis thaliana ACHT1
Descriptor: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ...
Authors:Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M.
Deposit date:2020-02-16
Release date:2020-05-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
6LYX
DownloadVisualize
BU of 6lyx by Molmil
Crystal structure of oxidized ACHT1
Descriptor: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ...
Authors:Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M.
Deposit date:2020-02-16
Release date:2020-05-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
8TFQ
DownloadVisualize
BU of 8tfq by Molmil
Fab from C10-S66K antibody in complex with fentanyl
Descriptor: Heavy chain from Fab of C10_S66K antibody, Light chain from Fab of C10_S66K antibody, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
Authors:Pholcharee, T, Wilson, I.A.
Deposit date:2023-07-11
Release date:2023-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
8TFR
DownloadVisualize
BU of 8tfr by Molmil
Apo Fab from C10-S66K antibody
Descriptor: Heavy chain from Fab of C10_S66K antibody, Immunoglobulin G-binding protein G, Light chain from Fab of C10_S66K antibody
Authors:Pholcharee, T, Wilson, I.A.
Deposit date:2023-07-11
Release date:2023-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
8TFP
DownloadVisualize
BU of 8tfp by Molmil
Fab from C10-S66K antibody in complex with carfentanil
Descriptor: Carfentanil, Heavy chain of Fab from C10-S66K antibody, Light chain of Fab from C10-S66K antibody
Authors:Pholcharee, T, Wilson, I.A.
Deposit date:2023-07-11
Release date:2023-08-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
8TM2
DownloadVisualize
BU of 8tm2 by Molmil
Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8TM0
DownloadVisualize
BU of 8tm0 by Molmil
Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class I polypeptide-related sequence A, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (3.83 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8TLZ
DownloadVisualize
BU of 8tlz by Molmil
Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: (2S)-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
1Y6O
DownloadVisualize
BU of 1y6o by Molmil
Crystal structure of disulfide engineered porcine pancreatic phospholipase A2 to group-X isozyme in complex with inhibitor MJ33 and phosphate ions
Descriptor: 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHATE ION, ...
Authors:Yu, B.Z, Pan, Y.H, Jassen, M.J.W, Bahnson, B.J, Jain, M.K.
Deposit date:2004-12-06
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural properties of disulfide engineered phospholipase a(2): insight into the role of disulfide bonding patterns.
Biochemistry, 44, 2005
1Y6P
DownloadVisualize
BU of 1y6p by Molmil
Crystal structure of disulfide engineered porcine pancratic phospholipase a2 to group-x isozyme
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Yu, B.Z, Pan, Y.H, Jassen, M.J.W, Bahnson, B.J, Jain, M.K.
Deposit date:2004-12-06
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Kinetic and structural properties of disulfide engineered phospholipase a(2): insight into the role of disulfide bonding patterns.
Biochemistry, 44, 2005
3RAE
DownloadVisualize
BU of 3rae by Molmil
Quinolone(Levofloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae
Descriptor: (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 5'-D(*CP*AP*TP*GP*AP*AP*T)-3', 5'-D(*CP*GP*TP*GP*CP*AP*T)-3', ...
Authors:Laponogov, I, Pan, X.-S, Veselkov, D.A, McAuley, K.E, Fisher, L.M, Sanderson, M.R.
Deposit date:2011-03-28
Release date:2012-04-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex.
Acta Crystallogr.,Sect.D, 72, 2016
3SD5
DownloadVisualize
BU of 3sd5 by Molmil
Crystal Structure of PI3K gamma with 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amine
Descriptor: 5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Authors:Knapp, M.S, Elling, R.A.
Deposit date:2011-06-08
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor.
Mol.Cancer Ther., 11, 2012
3PVL
DownloadVisualize
BU of 3pvl by Molmil
Structure of myosin VIIa MyTH4-FERM-SH3 in complex with the CEN1 of Sans
Descriptor: GLYCEROL, Myosin VIIa isoform 1, PHOSPHATE ION, ...
Authors:Wu, L, Pan, L.F, Wei, Z.Y, Zhang, M.J.
Deposit date:2010-12-07
Release date:2011-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Science, 331, 2011
3RAD
DownloadVisualize
BU of 3rad by Molmil
Quinolone(Clinafloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae
Descriptor: 5'-D(*CP*AP*TP*GP*AP*AP*T)-3', 5'-D(*CP*GP*TP*GP*CP*AP*T)-3', 5'-D(P*AP*GP*TP*CP*AP*TP*TP*CP*AP*TP*G)-3', ...
Authors:Laponogov, I, Pan, X.-S, Veselkov, D.A, McAuley, K.E, Fisher, L.M, Sanderson, M.R.
Deposit date:2011-03-28
Release date:2012-04-25
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones.
Open Biol, 6, 2016
4GJP
DownloadVisualize
BU of 4gjp by Molmil
Crystal structure of the TAL effector dHax3 bound to dsDNA containing repetitive methyl-CpG
Descriptor: DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*CP*T)-3'), Hax3, ...
Authors:Yan, N, Deng, D, Yan, C.Y, Yin, P, Pan, X.J, Shi, Y.G.
Deposit date:2012-08-10
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of a protein complex
To be Published
4GJR
DownloadVisualize
BU of 4gjr by Molmil
Crystal structure of the TAL effector dHax3 bound to methylated dsDNA
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P*CP*TP*CP*(5CM)P*CP*T)-3'), Hax3
Authors:Yan, N, Deng, D, Yan, C.Y, Yin, P, Pan, X.J, Shi, Y.G.
Deposit date:2012-08-10
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of a protein complex
To be Published
4GG4
DownloadVisualize
BU of 4gg4 by Molmil
Crystal structure of the TAL effector dHax3 bound to specific DNA-RNA hybrid
Descriptor: DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, RNA (5'-R(*AP*GP*AP*GP*AP*GP*AP*UP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3')
Authors:Yin, P, Deng, D, Yan, C.Y, Pan, X.J, Yan, N, Shi, Y.G.
Deposit date:2012-08-05
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Specific DNA-RNA hybrid recognition by TAL effectors
Cell Rep, 2, 2012
4I5M
DownloadVisualize
BU of 4i5m by Molmil
Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein Phosphorylation in Rat Brain
Descriptor: 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Serine/threonine-protein kinase PLK2
Authors:Aubele, D.L, Hom, R.K, Adler, M, Galemmo Jr, R.A, Bowers, S, Truong, A.P, Pan, H, Beroza, P, Neitz, R.J, Yao, N, Lin, M, Tonn, G, Zhang, H, Bova, M.P, Ren, Z, Tam, D, Ruslim, L, Baker, J, Diep, L, Fitzgerald, K, Hoffman, J, Motter, R, Fauss, D, Tanaka, P, Dappen, M, Jagodzinski, J, Chan, W, Konradi, A.W, Latimer, L, Zhu, Y.L, Artis, D.R, Sham, H.L, Anderson, J.P, Bergeron, M.
Deposit date:2012-11-28
Release date:2013-12-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce alpha-synuclein phosphorylation in rat brain.
Chemmedchem, 8, 2013
4I5P
DownloadVisualize
BU of 4i5p by Molmil
Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein Phosphorylation in Rat Brain
Descriptor: (7R)-8-cyclopentyl-7-ethyl-5-methyl-2-(1H-pyrrol-2-yl)-7,8-dihydropteridin-6(5H)-one, Serine/threonine-protein kinase PLK2
Authors:Aubele, D.L, Hom, R.K, Adler, M, Galemmo Jr, R.A, Bowers, S, Truong, A.P, Pan, H, Beroza, P.
Deposit date:2012-11-28
Release date:2013-12-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.738 Å)
Cite:Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce alpha-synuclein phosphorylation in rat brain.
Chemmedchem, 8, 2013
4I11
DownloadVisualize
BU of 4i11 by Molmil
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates.
Descriptor: Beta-secretase 1, N-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-L-phenylalanine, ZINC ION
Authors:Bowers, B, Xu, Y, Yuan, S, Probst, G.D, Hom, R.K, Chan, W, Konradi, A.W, Sham, H.L, Zhu, Y.L, Beroza, P, Pan, H, Brecht, E, Yao, N, Lougheed, J, Artis, D.R, Tam, D, Bova, M.
Deposit date:2012-11-19
Release date:2013-03-06
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates.
Bioorg.Med.Chem.Lett., 23, 2013
5J5Q
DownloadVisualize
BU of 5j5q by Molmil
AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type II
Descriptor: DNA (5'-D(*GP*CP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*GP*C)-3'), DNA topoisomerase 4 subunit B, MAGNESIUM ION, ...
Authors:Laponogov, I, Pan, X.-S, Skamrova, G, Umrekar, T, Fisher, L.M, Sanderson, M.R.
Deposit date:2016-04-03
Release date:2017-07-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase.
Nat Commun, 9, 2018
5JKG
DownloadVisualize
BU of 5jkg by Molmil
The crystal structure of FGFR4 kinase domain in complex with LY2874455
Descriptor: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4
Authors:Wu, D, Chen, L, Chen, Y.
Deposit date:2016-04-26
Release date:2016-10-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455
Plos One, 11, 2016
5J5P
DownloadVisualize
BU of 5j5p by Molmil
AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type I
Descriptor: DNA (5'-D(*GP*CP*GP*CP*GP*C)-3'), DNA topoisomerase 4 subunit B, MAGNESIUM ION, ...
Authors:Laponogov, I, Pan, X.-S, Skamrova, G, Umrekar, T, Fisher, L.M, Sanderson, M.R.
Deposit date:2016-04-03
Release date:2017-07-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase.
Nat Commun, 9, 2018

221051

건을2024-06-12부터공개중

PDB statisticsPDBj update infoContact PDBjnumon