8XT0
 
 | | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2024-01-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8XT3
 | | Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline | | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2024-01-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8XSZ
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2024-01-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8XSY
 | | Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2024-01-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8XT1
 | | Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline | | Descriptor: | 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2024-01-10 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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8RNH
 | | Crystal structure of HLA B*18:01 in complex with EEIEITTHF, an 9-mer epitope from Influenza A | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Murdolo, L.D, Maddumaage, J, Gras, S. | | Deposit date: | 2024-01-10 | | Release date: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of HLA B*18:01 in complex with EEIEITTHF, an 9-mer epitope from Influenza A
To Be Published
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8RNG
 | | Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGNESIUM ION, ... | | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | | Deposit date: | 2024-01-10 | | Release date: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A
To Be Published
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8VKR
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8VKQ
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8VKU
 | | Structure of VCP in complex with an ATPase activator (D2 domains only, hexameric form) | | Descriptor: | (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase | | Authors: | Jones, N.H, Urnivicius, L, Kapoor, T.M. | | Deposit date: | 2024-01-09 | | Release date: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8XS0
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8XRY
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8VK3
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8VK4
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8RMO
 | | Crystal structure of anti-FLAG M2 Fab fragment bound to FLAG-tag peptide epitope | | Descriptor: | CHLORIDE ION, FLAG-tag, anti-FLAG M2 heavy chain, ... | | Authors: | Beugelink, J.W, Janssen, B.J.C, Pronker, M.F. | | Deposit date: | 2024-01-08 | | Release date: | 2024-04-03 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.163 Å) | | Cite: | Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2.
J.Mol.Biol., 436, 2024
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8VKC
 | | Crystal structure of dehaloperoxidase A in complex with substrate 4-nitrophenol | | Descriptor: | Dehaloperoxidase A, GLYCEROL, P-NITROPHENOL, ... | | Authors: | Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. | | Deposit date: | 2024-01-08 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B.
Biochemistry, 2024
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8VKD
 | | Crystal structure of dehaloperoxidase A in complex with substrate 4-nitrocatechol | | Descriptor: | 4-NITROCATECHOL, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | Authors: | Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. | | Deposit date: | 2024-01-08 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B.
Biochemistry, 2024
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8VKA
 | | Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 9c | | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2024-01-08 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors.
J.Med.Chem., 67, 2024
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8VKB
 | | Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 10b | | Descriptor: | CHLORIDE ION, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase, ... | | Authors: | Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2024-01-08 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors.
J.Med.Chem., 67, 2024
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8VJK
 | | Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset) | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... | | Authors: | Weninger, G, Marks, A.R. | | Deposit date: | 2024-01-07 | | Release date: | 2024-01-17 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VJJ
 | | Structure of mouse RyR1 (EGTA-only dataset) | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... | | Authors: | Weninger, G, Marks, A.R. | | Deposit date: | 2024-01-07 | | Release date: | 2024-01-17 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Structural insights into the regulation of RyR1 by S100A1.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VJ6
 | | GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 1 | | Descriptor: | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, Isoform Flip of Glutamate receptor 2 | | Authors: | Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C. | | Deposit date: | 2024-01-05 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Allosteric competition and inhibition in AMPA receptors.
Nat.Struct.Mol.Biol., 2024
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8VJ7
 | | GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 2 | | Descriptor: | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2 | | Authors: | Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C. | | Deposit date: | 2024-01-05 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (4.85 Å) | | Cite: | Allosteric competition and inhibition in AMPA receptors.
Nat.Struct.Mol.Biol., 2024
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8RM5
 | | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'SS oligo, NHP2-like protein 1, ... | | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | | Deposit date: | 2024-01-05 | | Release date: | 2024-05-22 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
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8VIB
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